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Gut Microbial Metabotyping for Precision Medicine: A Case Study of Irinotecan Presentation
会议地点: Wuxi, China, 会议日期: Nov 10-13, 2023, 报告日期: 2023-11-01
Authors:  YAN RU
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Gut Microbial Metabotyping  Irinotecan  Glucuronidation  Precision Medicine  
Sanggenon g, a diels-alder adduct screened from mori cortex, attenuated irinotecan-induced gastrointestinal toxicity in mice through suppressing sn-38 intestinal accumulation via a dual inhibition mechanism. Conference proceedings
Prague, 2023-09
Authors:  YAN RU
Favorite |  | Submit date：2024/08/29
Gus Inhibitor  Sanggenon g  Diels-alder Adduct  Irinotecan-induced Toxicity  Oatp2b1 Inhibitor  Sn-38  
Fecal microbial SN-38G metabotypes in colorectal cancer patients are associated with irinotecan-induced delayed diarrhea Conference paper
Wu, Rongrong, Chen, Junru, Jia, Yifei, Chen, Yijia, Li, Yang, YAN RU. Fecal microbial SN-38G metabotypes in colorectal cancer patients are associated with irinotecan-induced delayed diarrhea[C], 2023.
Authors:  Wu, Rongrong;  Chen, Junru;  Jia, Yifei;  Chen, Yijia;  Li, Yang; et al.
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Sn-38g Metabotypes  Fecal Microbial Metabolism  Colorectal Cancer  Irinotecan-induced Delayed Diarrhea  Gut Microbial Β-glucuronidases  
Sanggenon G, a Diels-Alder Adduct Screened from Mori Cortex, Attenuated Irinotecan-induced Late-onset Diarrhea in Mice via a Dual Inhibition Mechanism Conference paper
YAN RU, Wang, Panpan, Chen, Zhiqiang, Wu, Rongrong, Jia, Yifei. Sanggenon G, a Diels-Alder Adduct Screened from Mori Cortex, Attenuated Irinotecan-induced Late-onset Diarrhea in Mice via a Dual Inhibition Mechanism[C], 2023.
Authors:  YAN RU;  Wang, Panpan;  Chen, Zhiqiang;  Wu, Rongrong;  Jia, Yifei
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Sanggenon g, a Screened From , Attenuated In Mice Via a Dual Inhibition Mechanism  Diels-alder Adduct  Mori Cortex  Gus Inhibitor  Irinotecan-induced Diarrhea  Oatp2b1 Inhibition  Dual Inhibition  
The correlation between gut microbial SN-38G metabotypes and irinotecan-induced gastrointestinal toxicity in colorectal cancer patients Conference proceedings
Beijing, May 18-22, 2023
Authors:  Wu, Rongrong;  YAN RU
Favorite |  | Submit date：2023/08/30
Gut Microbiota  Sn-38g Metabotypes  Irinotecan  Gastrointestinal Toxicity  Colorectal Cancer  
Fecal microbial SN-38G metabotypes in colorectal cancer patients are associated with irinotecan-induced gastrointestinal toxicity. Conference proceedings
Macao, Dec 2-4, 2022
Authors:  Wu, Rongrong;  Chen, Junru;  Jia, Yifei;  Chen, Yijia;  Yan, Ru
Favorite |  | Submit date：2023/05/20
Sn-38g Metabotypes  Colorectal Cancer  Irinotecan  Gastrointestinal Toxicity  Gut Microbiota  Beta-glucuronidases  
Fecal microbial SN-38G metabotypes in colorectal cancer patients are associated with irinotecan-induced gastrointestinal toxicity Conference proceedings
Dec 2-4, 2022
Authors:  Wu, Rongrong;  YAN RU
Favorite |  | Submit date：2023/08/31
Gut Microbiota  Sn-38g Metabotypes  Irinotecan-induced Gastrointestinal Toxicity.  Colorectal Cancer  
Toosendanin, a late-stage autophagy inhibitor, sensitizes triple-negative breast cancer to irinotecan chemotherapy Journal article
Zhang, Shuang, Dong, Yu, Chen, Xiuping, Tan, Chris Soon Heng, Li, Min, Miao, Kai, Lu, Jia Hong. Toosendanin, a late-stage autophagy inhibitor, sensitizes triple-negative breast cancer to irinotecan chemotherapy[J]. Chinese Medicine, 2022, 17, 55.
Authors:  Zhang, Shuang;  Dong, Yu;  Chen, Xiuping;  Tan, Chris Soon Heng;  Li, Min; et al.
Favorite | TC[WOS]:11 TC[Scopus]:12  IF:5.3/5.5 | Submit date：2022/05/31
Apoptosis  Autophagy Inhibition  Irinotecan  Lysosome  Sn-38  Toosendanin  Triple-negative Breast Cancer  
A four-component combination derived from Huang-Qin Decoction significantly enhances anticancer activity of irinotecan Journal article
XU, Dou Dou, HOU, Xiao Ying, WANG, Ou, WANG, Di, LI, Dan Ting, QIN, Si Yuan, LV, Bo, DAI, Xiao Min, ZHANG, Zun Jian, WAN, Jian Bo, XU, Feng Guo. A four-component combination derived from Huang-Qin Decoction significantly enhances anticancer activity of irinotecan[J]. Chinese Journal of Natural Medicines, 2021, 19(5), 364-375.
Authors:  XU, Dou Dou;  HOU, Xiao Ying;  WANG, Ou;  WANG, Di;  LI, Dan Ting; et al.
Favorite | TC[WOS]:20 TC[Scopus]:22  IF:4.0/3.7 | Submit date：2021/12/07
Active Components  Bioactivity Contribution  Huang-qin Decoction  Irinotecan  Toxicity Attenuating And Efficacy Enhancing  
Combination Inhibition of Gut Microbial β-Glucuronidase Metabolism and Intestinal Uptake by MSK Attenuated Irinotecan-induced Gastrointestinal Toxicity in Mice Conference proceedings
Authors:  Wang, Panpan;  Hou, Tingting;  Wu, Rongrong;  Yan, Ru
Favorite |  | Submit date：2022/08/15
Β-glucuronidases  Combination Inhibition  Gut Microbial Metabolism  Irinotecan  Gastrointestinal Toxicity  Intestinal Uptake  Sn-38g  Mori Cortex  Da Adducts