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Bulleyaconitine A is a sensitive substrate and competitive inhibitor of CYP3A4: One of the possible explanations for clinical adverse reactions Journal article
Li, Xiaocui, Ou, Xiaowen, Ni, Jiadong, Xu, Yihong, Zuo, Huilin, Fu, Yu, Yang, Caihua, Zhao, Zhongxiang, Li, Na, Zhou, Hua, Zhang, Rong, Liu, Zhongqiu, Fu, Ling, Zhu, Lijun. Bulleyaconitine A is a sensitive substrate and competitive inhibitor of CYP3A4: One of the possible explanations for clinical adverse reactions[J]. Toxicology and Applied Pharmacology, 2022, 445.
Authors:  Li, Xiaocui;  Ou, Xiaowen;  Ni, Jiadong;  Xu, Yihong;  Zuo, Huilin; et al.
Favorite | TC[WOS]:2 TC[Scopus]:2  IF:3.3/3.6 | Submit date：2023/01/30
Adverse Reaction  Bulleyaconitine a  Cytochrome P450 Enzymes  Drug-drug Interactions  Human Liver Microsomes  Metabolism  
Generation of Human Fatty Livers Using Custom-Engineered Induced Pluripotent Stem Cells with Modifiable SIRT1 Metabolism Journal article
Collin de l'Hortet,Alexandra, Takeishi,Kazuki, Guzman-Lepe,J., Morita,Kazutoyo, Achreja,Abhinav, Popovic,Branimir, Wang,Yang, Handa,Kan, Mittal,Anjali, Meurs,Noah, Zhu,Z., Weinberg,F., Salomon,Michael, Fox,I. J., Deng,Chu Xia, Nagrath,Deepak, Soto-Gutierrez,Alejandro. Generation of Human Fatty Livers Using Custom-Engineered Induced Pluripotent Stem Cells with Modifiable SIRT1 Metabolism[J]. Cell Metabolism, 2019, 30(2), 385-401.e9.
Authors:  Collin de l'Hortet,Alexandra;  Takeishi,Kazuki;  Guzman-Lepe,J.;  Morita,Kazutoyo;  Achreja,Abhinav; et al.
Favorite | TC[WOS]:67 TC[Scopus]:78  IF:27.7/31.2 | Submit date：2020/09/16
Cellular Engineering  Hepatic Differentiation  Human Fatty Liver  Human Ipscs  Liver Metabolism  Nafld  Nash  Sirt1  
Identification of cytochrome P450 isoenzymes involved in metabolism of (+)-praeruptorin A, a calcium channel blocker, by human liver microsomes using ultra high-performance liquid chromatography coupl Journal article
Jing, Wang-Hui, Song, Yue-Lin, Yan, Ru, Wang, Yi-Tao. Identification of cytochrome P450 isoenzymes involved in metabolism of (+)-praeruptorin A, a calcium channel blocker, by human liver microsomes using ultra high-performance liquid chromatography coupl[J]. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2013, 77, 175-188.
Authors:  Jing, Wang-Hui;  Song, Yue-Lin;  Yan, Ru;  Wang, Yi-Tao
Favorite | TC[WOS]:19 TC[Scopus]:18  IF:3.1/3.1 | Submit date：2018/11/01
Angular-type Pyranocoumarins  (+)-praeruptorin a  Uhplc–qt-ms/ms  Human Liver Microsomes  Cyp 3a4  
Identification of cytochrome P450 isoenzymes involved in metabolism of (+)-praeruptorin A, a calcium channel blocker, by human liver microsomes using ultra high-performance liquid chromatography coupled with tandem mass spectrometry Journal article
Jing W.-H., Song Y.-L., Yan R., Wang Y.-T.. Identification of cytochrome P450 isoenzymes involved in metabolism of (+)-praeruptorin A, a calcium channel blocker, by human liver microsomes using ultra high-performance liquid chromatography coupled with tandem mass spectrometry[J]. Journal of Pharmaceutical and Biomedical Analysis, 2013, 77, 175.
Authors:  Jing W.-H.;  Song Y.-L.;  Yan R.;  Wang Y.-T.
Favorite | TC[WOS]:19 TC[Scopus]:18  IF:3.1/3.1 | Submit date：2018/10/31
(+)-praeruptorin a  Angular-type Pyranocoumarins  Cytochrome Cyp 3a4  Metabolism  Human Liver Microsomes  Uhplc-qt-ms/ms  Chinese Medicines  Peucedani Radix  
Effects of Radix Astragali and Radix Rehmanniae, the components of an anti-diabetic foot ulcer herbal formula, on metabolism of model CYP1A2, CYP2C9, CYP2D6, CYP2E1 and CYP3A4 probe substrates in pooled human liver microsomes and specific CYP isoforms Journal article
Or P.M.Y., Lam F.F.Y., Kwan Y.W., Cho C.H., Lau C.P., Yu H., Lin G., Lau C.B.S., Fung K.P., Leung P.C., Yeung J.H.K.. Effects of Radix Astragali and Radix Rehmanniae, the components of an anti-diabetic foot ulcer herbal formula, on metabolism of model CYP1A2, CYP2C9, CYP2D6, CYP2E1 and CYP3A4 probe substrates in pooled human liver microsomes and specific CYP isoforms[J]. Phytomedicine, 2012, 19(6), 535-544.
Authors:  Or P.M.Y.;  Lam F.F.Y.;  Kwan Y.W.;  Cho C.H.;  Lau C.P.; et al.
Favorite | TC[WOS]:35 TC[Scopus]:38 | Submit date：2019/01/17
Cyp1a2  Cyp2c9  Cyp2d6  Cyp2e1  Cyp3a4  Human Liver Microsomes  Radix Astragali  Radix Rehmanniae  
Transport and metabolism of (+/-)-praeruptorin A in Caco-2 cell monolayers Journal article
Jing, W. H., Song, Y. L., Yan, R., Bi, H. C., Li, P. T., Wang, Y. T.. Transport and metabolism of (+/-)-praeruptorin A in Caco-2 cell monolayers[J]. XENOBIOTICA, 2011, 41(1), 71-81.
Authors:  Jing, W. H.;  Song, Y. L.;  Yan, R.;  Bi, H. C.;  Li, P. T.; et al.
Favorite | TC[WOS]:20 TC[Scopus]:21  IF:1.3/1.4 | Submit date：2018/11/01
Intestinal-absorption  Gene-expression  Drug Transport  Human Liver  Permeability  Carboxylesterases  Enantiomers  Ester  
Metabolism of 17a-hydroxyprogesterone caproate by hepatic and placental microsomes of human and baboons Journal article
Ru Yan, Tatiana N. Nanovskaya, Olga L. Zharikova, Donald R. Mattison, Gary D.V. Hankins, Mahmoud S. Ahmed. Metabolism of 17a-hydroxyprogesterone caproate by hepatic and placental microsomes of human and baboons[J]. Biochemical pharmacology, 2008, 75(9), 1848-1857.
Authors:  Ru Yan;  Tatiana N. Nanovskaya;  Olga L. Zharikova;  Donald R. Mattison;  Gary D.V. Hankins; et al.
Favorite | TC[WOS]:20 TC[Scopus]:18  IF:5.3/5.2 | Submit date：2019/01/15
Preterm Delivery  17a-hydroxyprogesterone Caproate  Metabolism  Microsomes  Human Placenta  Baboon Placenta  Human Liver  Baboon Liver