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KDM5 family as therapeutic targets in breast cancer: Pathogenesis and therapeutic opportunities and challenges Review article
2024
Authors:  Li, Chang Yun;  Wang, Wanhe;  Leung, Chung Hang;  Yang, Guan Jun;  Chen, Jiong
Favorite | TC[WOS]:2 TC[Scopus]:2  IF:27.7/31.3 | Submit date:2024/06/05
Breast Cancer  Histone Demethylation  Kdm5  Kdm5 Inhibitors  Therapeutic Target  
Mechanisms of carcinogenic activity triggered by lysine-specific demethylase 1A Journal article
Chao Yang, Dan Li, Shaohong Zang, Lei Zhang, Zhangfeng Zhong, Yingtang Zhou. Mechanisms of carcinogenic activity triggered by lysine-specific demethylase 1A[J]. Frontiers in Pharmacology, 2022, 13.
Authors:  Chao Yang;  Dan Li;  Shaohong Zang;  Lei Zhang;  Zhangfeng Zhong; et al.
Favorite | TC[WOS]:7 TC[Scopus]:7  IF:4.4/5.0 | Submit date:2022/08/24
Anticancer Activity  Demethylation  Epigenetics  Histone Modifications  Lsd1  Lysine Methylation  Signaling Pathway  Targets  
Structure-Based Discovery of a Selective KDM5A Inhibitor that Exhibits Anti-Cancer Activity via Inducing Cell Cycle Arrest and Senescence in Breast Cancer Cell Lines Journal article
Yang, GJ, Ko, CN, Zhong, HJ, Leung, CH, Ma, DL. Structure-Based Discovery of a Selective KDM5A Inhibitor that Exhibits Anti-Cancer Activity via Inducing Cell Cycle Arrest and Senescence in Breast Cancer Cell Lines[J]. CANCERS, 2019, 11(1).
Authors:  Yang, GJ;  Ko, CN;  Zhong, HJ;  Leung, CH;  Ma, DL
Favorite | TC[WOS]:54 TC[Scopus]:61  IF:4.5/4.9 | Submit date:2020/03/24
Cell Cycle Arrest  Kdm5a  Jumonji Domain  Histone Demethylation  Protein-protein Interaction  Virtual Screening  Breast Cancer  Cell Senescence