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Development of small molecule inhibitors targeting RNA helicase DHX33 as anti-cancer agents Journal article
Wang, Yingcai, Nie, Guangli, Wang, Xingshun, Ge, Wei, Zhang, Yandong. Development of small molecule inhibitors targeting RNA helicase DHX33 as anti-cancer agents[J]. Bioorganic and Medicinal Chemistry Letters, 2023, 96, 129505.
Authors:  Wang, Yingcai;  Nie, Guangli;  Wang, Xingshun;  Ge, Wei;  Zhang, Yandong
Favorite | TC[WOS]:2 TC[Scopus]:2  IF:2.5/2.4 | Submit date：2023/12/04
Cancer  Dhx33  Rna Helicase  Inhibitor High Throughput Screening (Hts)  
High-Throughput Screening of Heterogeneous Transition Metal Dual-Atom Catalysts by Synergistic Effect for Nitrate Reduction to Ammonia Journal article
Shu,Zheng, Chen,Hongfei, Liu,Xing, Jia,Huaxian, Yan,Hejin, Cai,Yongqing. High-Throughput Screening of Heterogeneous Transition Metal Dual-Atom Catalysts by Synergistic Effect for Nitrate Reduction to Ammonia[J]. Advanced Functional Materials, 2023, 33(32).
Authors:  Shu,Zheng;  Chen,Hongfei;  Liu,Xing;  Jia,Huaxian;  Yan,Hejin; et al.
Favorite | TC[WOS]:29 TC[Scopus]:50  IF:18.5/19.6 | Submit date：2023/08/03
Dual-atom Catalysts  High-throughput Screening  Nitrate Reduction  
Mapping the regulatory effects of herbal organic compounds on gut bacteria Journal article
Zhang,Yulong, Chen,Ting, Hao,Xiaoqing, Hu,Yuanjia, Chen,Manyun, Zhang,Daiyan, Cai,Hong, Luo,Jun, Kong,Lingyi, Huang,Sutianzi, Huang,Yuanfei, Yang,Nian, Liu,Rong, Li,Qing, Yuan,Chunsu, Wang,Chongzhi, Zhou,Honghao, Huang,Weihua, Zhang,Wei. Mapping the regulatory effects of herbal organic compounds on gut bacteria[J]. Pharmacological Research, 2023, 193, 106804.
Authors:  Zhang,Yulong;  Chen,Ting;  Hao,Xiaoqing;  Hu,Yuanjia;  Chen,Manyun; et al.
Favorite | TC[WOS]:2 TC[Scopus]:2  IF:9.1/9.0 | Submit date：2023/08/03
Anticommensal Activity  Gut Microbiota  Herbal Organic Compounds  High-throughput Screening  Human Microbiome  
High-throughput screening for amyloid-β binding natural small-molecules based on the combinational use of biolayer interferometry and UHPLC−DAD-Q/TOF-MS/MS Journal article
Guo, Minsong, Zhu, Fengdan, Qiu, Wenqiao, Qiao, Gan, Law, Betty Yuen Kwan, Yu, Lu, Wu, Jianming, Tang, Yong, Yu, Chonglin, Qin, Dalian, Zhou, Xiaogang, Wu, Anguo. High-throughput screening for amyloid-β binding natural small-molecules based on the combinational use of biolayer interferometry and UHPLC−DAD-Q/TOF-MS/MS[J]. Acta Pharmaceutica Sinica B, 2022, 12(4), 1723-1739.
Authors:  Guo, Minsong;  Zhu, Fengdan;  Qiu, Wenqiao;  Qiao, Gan;  Law, Betty Yuen Kwan; et al.
Favorite | TC[WOS]:33 TC[Scopus]:37  IF:14.7/14.1 | Submit date：2023/01/30
Alzheimer's Disease  Biolayer Interferometry  High-throughput Screening  Kai-xin-san  Uhplc−dad-q/tof-ms/ms  
Time-resolved luminescent high-throughput screening platform for lysosomotropic compounds in living cells Journal article
Wu,Ke Jia, Wu,Chun, Chen,Feng, Cheng,Sha Sha, Ma,Dik Lung, Leung,Chung Hang. Time-resolved luminescent high-throughput screening platform for lysosomotropic compounds in living cells[J]. ACS Sensors, 2020, 6(1), 166-174.
Authors:  Wu,Ke Jia;  Wu,Chun;  Chen,Feng;  Cheng,Sha Sha;  Ma,Dik Lung; et al.
Favorite | TC[WOS]:7 TC[Scopus]:9  IF:8.2/8.4 | Submit date：2021/03/01
High-throughput Screening  Iridium-based Ph Probe  Lysosomotropic Compounds  Mitoxantrone  Time-resolved Emission Spectroscopy  
A Three-Way Combinatorial CRISPR Screen for Analyzing Interactions among Druggable Targets Journal article
Zhou,Peng, Chan,Becky K.C., Wan,Yuk Kei, Yuen,Chaya T.L., Choi,Gigi C.G., Li,Xinran, Tong,Cindy S.W., Zhong,Sophia S.W., Sun,Jieran, Bao,Yufan, Mak,Silvia Y.L., Chow,Maggie Z.Y., Khaw,Jien Vei, Leung,Suet Yi, Zheng,Zongli, Cheung,Lydia W.T., Tan,Kaeling, Wong,Koon Ho, Chan,H. Y.Edwin, Wong,Alan S.L.. A Three-Way Combinatorial CRISPR Screen for Analyzing Interactions among Druggable Targets[J]. Cell Reports, 2020, 32(6), 108020.
Authors:  Zhou,Peng;  Chan,Becky K.C.;  Wan,Yuk Kei;  Yuen,Chaya T.L.;  Choi,Gigi C.G.; et al.
Favorite | TC[WOS]:25 TC[Scopus]:26  IF:7.5/8.5 | Submit date：2021/03/04
Cancer  Combigem  Combination Therapy  Combinatorial Genetics  Crispr  Drug Interaction  Genetic Interaction  High-throughput Screening  Neurodegeneration  Parkinson's Disease  
Cell-based drug screening on microfluidics Review article
2019
Authors:  Jiao Zhai;  Shuhong Yi;  Yanwei Jia;  Pui-In Mak;  Rui P. Martins
Favorite | TC[WOS]:46 TC[Scopus]:56  IF:11.8/12.7 | Submit date：2021/03/04
Continuous-flow Based Microfluidics  Droplet Microfluidics  Digital Microfluidics  Paper Microfluidics  Sing Cell Drug Screening  High-throughput Drug Screening  3d Cell-based Drug Screening  
Identification of Novel Pyruvate Dehydrogenase Kinase 1 (PDK1) Inhibitors by Kinase Activity-Based High-Throughput Screening for Anticancer Therapeutics Journal article
Zhang W., Hu X., Chakravarty H., Yang Z., Tam K.Y.. Identification of Novel Pyruvate Dehydrogenase Kinase 1 (PDK1) Inhibitors by Kinase Activity-Based High-Throughput Screening for Anticancer Therapeutics[J]. ACS Combinatorial Science, 2018, 20(11), 660-671.
Authors:  Zhang W.;  Hu X.;  Chakravarty H.;  Yang Z.;  Tam K.Y.
Favorite | TC[WOS]:12 TC[Scopus]:12 | Submit date：2018/12/18
Cancer  High-throughput Screening  Pyruvate Dehydrogenase Kinase 1  Small Molecule Inhibitors  Warburg Effect  
Identification of Novel Pyruvate Dehydrogenase Kinase 1 (PDK1) Inhibitors by Kinase Activity-Based High-Throughput Screening for Anticancer Therapeutics Journal article
Zhang, W., Hu, X., Chakravarty, H., Yang, Z., Tam, K. Y.. Identification of Novel Pyruvate Dehydrogenase Kinase 1 (PDK1) Inhibitors by Kinase Activity-Based High-Throughput Screening for Anticancer Therapeutics[J]. ACS Combinatoral Science, 2018, 660-671.
Authors:  Zhang, W.;  Hu, X.;  Chakravarty, H.;  Yang, Z.;  Tam, K. Y.
Favorite | TC[WOS]:12 TC[Scopus]:12  IF:3.903/3.637 | Submit date：2022/07/28
Cancer  Warburg Effect  High-throughput Screening  Pyruvate Dehydrogenase Kinase 1  Small Molecule Inhibitors  
Neural stem cells for disease modeling and evaluation of therapeutics for Tay-Sachs disease Journal article
Vu, Mylinh, Li, Rong, Baskfield, Amanda, Lu, Billy, Farkhondeh, Atena, Gorshkov, Kirill, Motabar, Omid, Beers, Jeanette, Chen, Guokai, Zou, Jizhong, Espejo-Mojica, Angela J., Rodriguez-Lopez, Alexander, Almeciga-Diaz, Carlos J., Barrera, Luis A., Jiang, Xuntian, Ory, Daniel S., Marugan, Juan J., Zheng, Wei. Neural stem cells for disease modeling and evaluation of therapeutics for Tay-Sachs disease[J]. ORPHANET JOURNAL OF RARE DISEASES, 2018, 13.
Authors:  Vu, Mylinh;  Li, Rong;  Baskfield, Amanda;  Lu, Billy;  Farkhondeh, Atena; et al.
Favorite | TC[WOS]:25 TC[Scopus]:31  IF:3.4/3.9 | Submit date：2018/10/30
Tay-sachs Disease  Induced Pluripotent Stem Cells  Neural Stem Cells  Cyclodextrin  Hp Beta Cd  Delta-tocopherol  Enzyme Replacement Therapy  Hexosaminidase a  Gm2 Gangliosidosis  High Throughput Screening  Drug Discovery