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Isoalantolactone/hydroxamic acid hybrids as potent dual STAT3/HDAC inhibitors and self-assembled nanoparticles for cancer therapy Journal article
Mo, Hualong, Liu, Jie Ying, Su, Zhengxi, Zhao, Deng Gao, Ma, Yan Yan, Zhang, Kun, Wang, Qi, Fu, Chun, Wang, Yao, Chen, Meiwan, Hu, Burong. Isoalantolactone/hydroxamic acid hybrids as potent dual STAT3/HDAC inhibitors and self-assembled nanoparticles for cancer therapy[J]. European Journal of Medicinal Chemistry, 2024, 277, 116765.
Authors:  Mo, Hualong;  Liu, Jie Ying;  Su, Zhengxi;  Zhao, Deng Gao;  Ma, Yan Yan; et al.
Favorite | TC[WOS]:1 TC[Scopus]:1  IF:6.0/6.1 | Submit date：2024/09/03
Hdac  Self-assembled Nanoparticles  Stat3  Isoalantolactone  Antitumor  
Dual inhibitors of DNMT and HDAC remodels the immune microenvironment of colorectal cancer and enhances the efficacy of anti-PD-L1 therapy Journal article
Yang ZhanBo, Chu BiZhu, Tu Yao, Li LuLu, Chen DaWei, Huang ShouHui, Huang WenJun, Fan WeiWen, Li QinYuan, Zhang CunLong, Yuan ZiGao, Huang Jumin, Leung Elaine Lai Han, Jiang Yuyang. Dual inhibitors of DNMT and HDAC remodels the immune microenvironment of colorectal cancer and enhances the efficacy of anti-PD-L1 therapy[J]. Pharmacological Research, 2024, 206, 107271.
Authors:  Yang ZhanBo;  Chu BiZhu;  Tu Yao;  Li LuLu;  Chen DaWei; et al.
Favorite | TC[WOS]:2 TC[Scopus]:2  IF:9.1/9.0 | Submit date：2024/06/17
Dnmt  Hdac  Rig-i/mda5-mavs  Anti-pd-l1 Therapy  Tumor Immune Microenvironment  
CTCF acetylation at lysine 20 is required for the early cardiac mesoderm differentiation of embryonic stem cells Journal article
Shixin Gong, Gongcheng Hu, Rong Guo, Jie Zhang, Yiqi Yang, Binrui Ji, Gang Li, Hongjie Yao. CTCF acetylation at lysine 20 is required for the early cardiac mesoderm differentiation of embryonic stem cells[J]. Cell Regeneration, 2022, 11(1), 34.
Authors:  Shixin Gong;  Gongcheng Hu;  Rong Guo;  Jie Zhang;  Yiqi Yang; et al.
Favorite | TC[WOS]:3 TC[Scopus]:3 | Submit date：2023/01/30
Cbp  Ctcf  Ctcf Acetylation  Early Cardiac Mesoderm Differentiation  Hdac6  
Celastrol inhibits lung cancer growth by triggering histone acetylation and acting synergically with HDAC inhibitors Journal article
Chen, Geer, Zhu, Xiaoyu, Li, Jiaqi, Zhang, Yao, Wang, Xiaoxuan, Zhang, Ren, Qin, Xinchen, Chen, Xi, Wang, Junyi, Liao, Weilin, Wu, Zongjin, Lu, Lu, Wu, Weiyu, Yu, Haijie, Ma, Lijuan. Celastrol inhibits lung cancer growth by triggering histone acetylation and acting synergically with HDAC inhibitors[J]. Pharmacological Research, 2022, 185.
Authors:  Chen, Geer;  Zhu, Xiaoyu;  Li, Jiaqi;  Zhang, Yao;  Wang, Xiaoxuan; et al.
Favorite | TC[WOS]:19 TC[Scopus]:21  IF:9.1/9.0 | Submit date：2023/01/31
Acetylation  Anacardic ACid (Pubchem Cid: 167551)  C646 (Pubchem Cid: 1285941)  Celastrol  Celastrol (Pubchem Cid: 122724)  Ci994 (Pubchem Cid: 2746)  Hdac  Histone Modification  Lung Cancer  Mc1568 (Pubchem Cid: 71311876)  Ms275 (Pubchem Cid: 4261)  Nu9056 (Pubchem Cid: 72201043)  Saha (Pubchem Cid: 5311)  
Sp1 S-Sulfhydration Induced by Hydrogen Sulfide Inhibits Inflammation via HDAC6/MyD88/NF-κB Signaling Pathway in Adjuvant-Induced Arthritis Journal article
Li, Meng, Hu, Wei, Wang, Ran, Li, Zhaoyi, Yu, Yue, Zhuo, Yue, Zhang, Yida, Wang, Zhou, Qiu, Yuanye, Chen, Keyuan, Ding, Qian, Qi, Wei, Zhu, Menglin, Zhu, Yizhun. Sp1 S-Sulfhydration Induced by Hydrogen Sulfide Inhibits Inflammation via HDAC6/MyD88/NF-κB Signaling Pathway in Adjuvant-Induced Arthritis[J]. Antioxidants, 2022, 11(4).
Authors:  Li, Meng;  Hu, Wei;  Wang, Ran;  Li, Zhaoyi;  Yu, Yue; et al.
Favorite | TC[WOS]:18 TC[Scopus]:19  IF:6.0/6.7 | Submit date：2023/01/30
H2 s  Hdac6  Rheumatoid Arthritis  Sp1  
Class I histone deacetylase inhibition is synthetic lethal with BRCA1 deficiency in breast cancer cells Journal article
Zhang,Baoyuan, Lyu,Junfang, Yang,Eun Ju, Liu,Yifan, Wu,Changjie, Pardeshi,Lakhansing, Tan,Kaeling, Chen,Qiang, Xu,Xiaoling, Deng,Chu Xia, Shim,Joong Sup. Class I histone deacetylase inhibition is synthetic lethal with BRCA1 deficiency in breast cancer cells[J]. Acta Pharmaceutica Sinica B, 2020, 10(4), 615-627.
Authors:  Zhang,Baoyuan;  Lyu,Junfang;  Yang,Eun Ju;  Liu,Yifan;  Wu,Changjie; et al.
Favorite | TC[WOS]:26 TC[Scopus]:29  IF:14.7/14.1 | Submit date：2020/09/16
Brca1  Histone Deacetylase  Hdac  Synthetic Lethality  Reactive Oxygen Species  Dna Damage  Breast Cancer  
A transcriptional repressor co-regulatory network governing androgen response in prostate cancers Journal article
Chng K.R., Chang C.W., Tan S.K., Yang C., Hong S.Z., Sng N.Y.W., Cheung E.. A transcriptional repressor co-regulatory network governing androgen response in prostate cancers[J]. EMBO Journal, 2012, 31(12), 2810-2823.
Authors:  Chng K.R.;  Chang C.W.;  Tan S.K.;  Yang C.;  Hong S.Z.; et al.
Favorite | TC[WOS]:135 TC[Scopus]:140 | Submit date：2018/12/17
Androgen Receptor  Ezh2  Hdac  Prostate Cancer  Tmprss2:Erg  
Recent advances in breast cancer metastasis suppressor 1 Journal article
Chen XP, Xu ZT, Wang YT. Recent advances in breast cancer metastasis suppressor 1[J]. International Journal of Biological Markers, 2011, 26(1), 1-8.
Authors:  Chen XP;  Xu ZT;  Wang YT
Favorite | TC[WOS]:16 TC[Scopus]:15  IF:2.3/2.3 | Submit date：2018/11/28
Brms1  Gap Junctional Intercellular Communication  Msin3-hdac  Microrna  Nf-kb