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Introducing enzymatic cleavage features and transfer learning realizes accurate peptide half-life prediction across species and organs Journal article
Tan, Xiaorong, Liu, Qianhui, Fang, Yanpeng, Yang, Sen, Chen, Fei, Wang, Jianmin, Ouyang, Defang, Dong, Jie, Zeng, Wenbin. Introducing enzymatic cleavage features and transfer learning realizes accurate peptide half-life prediction across species and organs[J]. Briefings in Bioinformatics, 2024, 25(4), bbae350.
Authors:  Tan, Xiaorong;  Liu, Qianhui;  Fang, Yanpeng;  Yang, Sen;  Chen, Fei; et al.
Favorite | TC[WOS]:1 TC[Scopus]:1  IF:6.8/7.9 | Submit date：2024/08/05
Drug Design  Enzymatic Cleavage Features  Half-life  Machine Learning  Peptide Drugs  Transfer Learning  
A paclitaxel prodrug with bifunctional folate and albumin binding moieties for both passive and active targeted cancer therapy Journal article
Shan L., Zhuo X., Zhang F., Dai Y., Zhu G., Yung B.C., Fan W., Zhai K., Jacobson O., Kiesewetter D.O., Ma Y., Gao G., Chen X.. A paclitaxel prodrug with bifunctional folate and albumin binding moieties for both passive and active targeted cancer therapy[J]. Theranostics, 2018, 8(7), 2018-2030.
Authors:  Shan L.;  Zhuo X.;  Zhang F.;  Dai Y.;  Zhu G.; et al.
Favorite | TC[WOS]:44 TC[Scopus]:43 | Submit date：2019/01/15
Circulation Half-life  Evans Blue  Paclitaxel Prodrug  Tumor Therapy  
A new bispecific antibody targeting non-overlapping epitopes on IGF2: design, in vitro characterization and pharmacokinetics in macaques Journal article
Feng, Y., Zhao, Q., Chen, W., Wang, Y., Crowder, K., Dimitrov, D.. A new bispecific antibody targeting non-overlapping epitopes on IGF2: design, in vitro characterization and pharmacokinetics in macaques[J]. Experimental and molecular pathology, 2014, 359-367.
Authors:  Feng, Y.;  Zhao, Q.;  Chen, W.;  Wang, Y.;  Crowder, K.; et al.
Favorite |   IF:2.8/2.7 | Submit date：2023/08/30
Bispecific antibodies  Cynomolgus macaques  Half-life  IGF ligand.  
A new bispecific antibody targeting non-overlapping epitopes on IGF2: Design, in vitro characterization and pharmacokinetics in macaques Journal article
Feng Y., Zhao Q., Chen W., Wang Y., Crowder K., Dimitrov D.S.. A new bispecific antibody targeting non-overlapping epitopes on IGF2: Design, in vitro characterization and pharmacokinetics in macaques[J]. Experimental and Molecular Pathology, 2014, 97(3), 359-367.
Authors:  Feng Y.;  Zhao Q.;  Chen W.;  Wang Y.;  Crowder K.; et al.
Favorite | TC[WOS]:14 TC[Scopus]:14 | Submit date：2019/01/16
Bispecific Antibodies  Cynomolgus Macaques  Half-life  Igf Ligand