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Glucuronidation Homeostasis in Colorectal Cancer: New Mechanistic Insights into Carcinogenesis and Precision Medicine Presentation
会议地点: Macao, 会议日期: Aug 24-26, 2024, 报告日期: 2024-08-01
Authors:  YAN RU
Adobe PDF | Favorite |  | Submit date：2024/08/31
Glucuronidation Homeostasis  Colorectal Cancer  Precision Medicine  Gut Microbial Β-glucuronidases  Gus Inhibitor  
Sanggenon g, a diels-alder adduct screened from mori cortex, attenuated irinotecan-induced gastrointestinal toxicity in mice through suppressing sn-38 intestinal accumulation via a dual inhibition mechanism. Conference proceedings
Prague, 2023-09
Authors:  YAN RU
Favorite |  | Submit date：2024/08/29
Gus Inhibitor  Sanggenon g  Diels-alder Adduct  Irinotecan-induced Toxicity  Oatp2b1 Inhibitor  Sn-38  
Sanggenon G, a Diels-Alder Adduct Screened from Mori Cortex, Attenuated Irinotecan-induced Late-onset Diarrhea in Mice via a Dual Inhibition Mechanism Conference paper
YAN RU, Wang, Panpan, Chen, Zhiqiang, Wu, Rongrong, Jia, Yifei. Sanggenon G, a Diels-Alder Adduct Screened from Mori Cortex, Attenuated Irinotecan-induced Late-onset Diarrhea in Mice via a Dual Inhibition Mechanism[C], 2023.
Authors:  YAN RU;  Wang, Panpan;  Chen, Zhiqiang;  Wu, Rongrong;  Jia, Yifei
Favorite |  | Submit date：2024/08/31
Sanggenon g, a Screened From , Attenuated In Mice Via a Dual Inhibition Mechanism  Diels-alder Adduct  Mori Cortex  Gus Inhibitor  Irinotecan-induced Diarrhea  Oatp2b1 Inhibition  Dual Inhibition  
葡萄糖醛酸化代谢稳态与结直肠癌：病理机制和个体化用药 (Glucuronidation metabolic homeostasis and colorectal cancer: pathological mechanisms and personalized medicine) Presentation
会议地点: The 10th National Congress of Toxicology 第十届全國毒理學大會。橫琴, 会议日期: Apr 8-11, 2023, 报告日期: 2023-04-09
Authors:  Yan, Ru
Favorite |  | Submit date：2023/05/20
Glucuronidation Homeostasis  Colorectal Cancer  Personalized Medicine  Beta-glucuronidases  Gus Inhibitor  
Inhibition and structure-activity relationship of dietary flavones against three Loop 1 human gut microbial β-glucuronidases Journal article
Wang, Panpan, Wu, Rongrong, Jia, Yifei, Tang, Puipui, Zhang, Qingwen, Wang, Yafan, Yan, Ru. Inhibition and structure-activity relationship of dietary flavones against three Loop 1 human gut microbial β-glucuronidases[J]. International Journal of Biological Macromolecules, 2022, 220, 1532-1544.
Authors:  Wang, Panpan;  Wu, Rongrong;  Jia, Yifei;  Tang, Puipui;  Zhang, Qingwen; et al.
Favorite |   IF:7.7/7.7 | Submit date：2022/08/30
Gut Microbial Metabolism  Β-glucuronidases  Gus Inhibitor  Flavones  Structure-activity Relationship  Allosteric Inhibition  
Applications of BGUSs inhibition in tumor prevention and chemotherapy Journal article
Wu RR(吴蓉蓉), Chen ZQ(陈智强), Jia YF(贾翼菲), Chen HQ(陈宏绮), Wang PP(王盼盼), Yan R(燕茹). Applications of BGUSs inhibition in tumor prevention and chemotherapy[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2021, 26(8), 964-974.
Authors:  Wu RR(吴蓉蓉);  Chen ZQ(陈智强);  Jia YF(贾翼菲);  Chen HQ(陈宏绮);  Wang PP(王盼盼); et al.
Favorite |  | Submit date：2022/07/31
Gut Microbiota  Β-glucuronidases  Cancer Risk  Chemotherapy  Gus Inhibitor  
Human gut bacterial β-glucuronidase inhibition: An emerging approach to manage medication therapy Journal article
Wang, Panpan, Jia, Yifei, Wu, Rongrong, Chen, Zhiqiang, Yan, Ru. Human gut bacterial β-glucuronidase inhibition: An emerging approach to manage medication therapy[J]. Biochemical Pharmacology, 2021, 190, 114566.
Authors:  Wang, Panpan;  Jia, Yifei;  Wu, Rongrong;  Chen, Zhiqiang;  Yan, Ru
Favorite | TC[WOS]:30 TC[Scopus]:41  IF:5.3/5.2 | Submit date：2021/12/08
Β-glucuronidases  Gut Microbial Metabolism  Drug Toxicity  Gus Inhibitor  Gut Microbiota  
Structure-activity relationship of phenolic compounds against human gut bacterial β-glucuronidases Conference proceedings
Beijing, China
Authors:  Wang, Panpan;  Tang, Puipui;  Wei, Bin;  Zhang, Qingwen;  Yan, Ru
Favorite |  | Submit date：2022/08/15
Β-glucuronidases  Structure-activity Relationship  Flavonoids  Gus Inhibitor  Gut Microbiota  
β-Glucuronidase from Staphylococcus pasteuri 3I10: Activity, inhibition and expression Conference proceedings
Authors:  Yan R(燕茹)
Favorite |  | Submit date：2022/08/15
Β-glucuronidase  Staphylococcus Pasteuri  Gut Microbiota  Deglucuronidation  Gus Inhibitor  Gut Microbial Metabolism  
MSG: a potent and highly selective bacterial β-glucuronidase inhibitor Conference proceedings
Authors:  Wei, Bin;  Yang, Wei;  Yan, Ru
Favorite |  | Submit date：2022/08/15
Β-glucuronidases  Diels-alder Adduct  Selective Inhibition  Gut Microbiota  Gus Inhibitor  Mori Cortex