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Formyl Peptide Receptor 2 Deficiency Improves Cognition and Attenuates Tau Hyperphosphorylation and Astrogliosis in a Mouse Model of Alzheimer's Disease Journal article
Zhang, Haibo, Wang, Ding, Gong, Ping, Lin, Aihua, Zhang, Yan, Ye, Richard D., Yu, Yang. Formyl Peptide Receptor 2 Deficiency Improves Cognition and Attenuates Tau Hyperphosphorylation and Astrogliosis in a Mouse Model of Alzheimer's Disease[J]. Journal of Alzheimer's Disease, 2019, 67(1), 169-179.
Authors:  Zhang, Haibo;  Wang, Ding;  Gong, Ping;  Lin, Aihua;  Zhang, Yan; et al.
Favorite | TC[WOS]:19 TC[Scopus]:18  IF:3.4/4.2 | Submit date：2022/05/23
Alzheimer's Disease  Astrocyte Activation  Formyl Peptide Receptor 2  Tau Phosphorylation  
4-Aroyl-3-hydroxy-5-phenyl-1H-pyrrol-2(5H)-ones as N-formyl peptide receptor 1 (FPR1) antagonists Journal article
Kirpotina, Liliya N., Schepetkin, Igor A., Khlebnikov, Andrei I., Ruban, Olga I., Ge, Yunjun, Ye, Richard D., Kominsky, Douglas J., Quinn, Mark T.. 4-Aroyl-3-hydroxy-5-phenyl-1H-pyrrol-2(5H)-ones as N-formyl peptide receptor 1 (FPR1) antagonists[J]. BIOCHEMICAL PHARMACOLOGY, 2017, 142, 120-132.
Authors:  Kirpotina, Liliya N.;  Schepetkin, Igor A.;  Khlebnikov, Andrei I.;  Ruban, Olga I.;  Ge, Yunjun; et al.
Favorite | TC[WOS]:29 TC[Scopus]:28  IF:5.3/5.2 | Submit date：2018/10/30
Antagonist Formyl Peptide Receptor  1h-pyrrol-2(5h)-one  Neutrophil  Molecular Modeling  
Synthesis of Five- and Six-Membered N-Phenylacetamido Substituted Heterocycles as Formyl Peptide Receptor Agonists Journal article
Vergelli, Claudia, Schepetkin, Igor A., Ciciani, Giovanna, Cilibrizzi, Agostino, Crocetti, Letizia, Giovannoni, Maria Paola, Guerrini, Gabriella, Iacovone, Antonella, Kirpotina, Liliya N., Ye, Richard D., Quinn, Mark T.. Synthesis of Five- and Six-Membered N-Phenylacetamido Substituted Heterocycles as Formyl Peptide Receptor Agonists[J]. DRUG DEVELOPMENT RESEARCH, 2017, 78(1), 49-62.
Authors:  Vergelli, Claudia;  Schepetkin, Igor A.;  Ciciani, Giovanna;  Cilibrizzi, Agostino;  Crocetti, Letizia; et al.
View | Adobe PDF | Favorite | TC[WOS]:8 TC[Scopus]:8  IF:3.5/4.0 | Submit date：2018/10/30
Formyl Peptide Receptor  Agonist  Pyridazin-3(2h)-one  Neutrophil  ca2+flux  
2-Arylacetamido-4-phenylamino-5-substituted pyridazinones as formyl peptide receptors agonists Journal article
Vergelli C., Schepetkin I.A., Ciciani G., Cilibrizzi A., Crocetti L., Giovannoni M.P., Guerrini G., Iacovone A., Kirpotina L.N., Khlebnikov A.I., Ye R.D., Quinn M.T.. 2-Arylacetamido-4-phenylamino-5-substituted pyridazinones as formyl peptide receptors agonists[J]. Bioorganic and Medicinal Chemistry, 2016, 24(11), 2530-2543.
Authors:  Vergelli C.;  Schepetkin I.A.;  Ciciani G.;  Cilibrizzi A.;  Crocetti L.; et al.
Favorite | TC[WOS]:21 TC[Scopus]:21 | Submit date：2018/11/07
Agonist  Ca2++ Mobilization  Formyl Peptide Receptor (Fpr)  Neutrophil  Pyridazin-3(2h)-one  
V101L of human formyl peptide receptor 1 (FPR1) increases receptor affinity and augments the antagonism mediated by cyclosporins Journal article
Zhou C., Zhou Y., Wang J., Feng Y., Wang H., Xue J., Chen Y., Ye R.D., Wang M.-W.. V101L of human formyl peptide receptor 1 (FPR1) increases receptor affinity and augments the antagonism mediated by cyclosporins[J]. Biochemical Journal, 2013, 451(2), 245-255.
Authors:  Zhou C.;  Zhou Y.;  Wang J.;  Feng Y.;  Wang H.; et al.
Favorite | TC[WOS]:12 TC[Scopus]:14 | Submit date：2018/11/07
Cyclosporin  Formyl Peptide Receptor 1 (Fpr1)  Haplotype  Pharmacogenomics  Receptor Affinity  Single Nucleotide Polymorphism  
Characterization of Quin-C1 for its anti-inflammatory property in a mouse model of bleomycin-induced lung injury Journal article
He M., Cheng N., Gao W.-W., Zhang M., Zhang Y.-Y., Ye R.D., Wang M.-W.. Characterization of Quin-C1 for its anti-inflammatory property in a mouse model of bleomycin-induced lung injury[J]. Acta Pharmacologica Sinica, 2011, 32(5), 601-610.
Authors:  He M.;  Cheng N.;  Gao W.-W.;  Zhang M.;  Zhang Y.-Y.; et al.
Favorite | TC[WOS]:32 TC[Scopus]:33 | Submit date：2018/11/07
Anti-inflammation  Bleomycin  Cytokines  Formyl Peptide Receptor  Lung Injury  Quin-c1  
Identification of functional domains in the formyl peptide receptor-like 1 for agonist-induced cell chemotaxis Journal article
Le Y., Ye R.D., Gong W., Li J., Iribarren P., Wang J.M.. Identification of functional domains in the formyl peptide receptor-like 1 for agonist-induced cell chemotaxis[J]. FEBS Journal, 2005, 272(3), 769-778.
Authors:  Le Y.;  Ye R.D.;  Gong W.;  Li J.;  Iribarren P.; et al.
Favorite | TC[WOS]:34 TC[Scopus]:34 | Submit date：2018/11/07
Chemotaxis  Formyl Peptide Receptor  Formyl Peptide Receptor-like 1  Structure-function  
Novel chemoattractant peptides for human leukocytes Journal article
Bae Y.-S., Park E.-Y., Kim Y., He R., Ye R.D., Kwak J.-Y., Suh P.-G., Ryu S.H.. Novel chemoattractant peptides for human leukocytes[J]. Biochemical Pharmacology, 2003, 66(9), 1841-1851.
Authors:  Bae Y.-S.;  Park E.-Y.;  Kim Y.;  He R.;  Ye R.D.; et al.
Favorite | TC[WOS]:13 TC[Scopus]:13 | Submit date：2018/11/07
Chemotaxis  Formyl Peptide Receptor Like 1  Peptide  Phagocytes  Phospholipase A2  Superoxide  
Characterization of chenodeoxycholic acid as an endogenous antagonist of the G-coupled formyl peptide receptors Journal article
Chen X., Yang D., Shen W., Dong H.F., Wang J.M., Oppenheim J.J., Howard O.M.Z.. Characterization of chenodeoxycholic acid as an endogenous antagonist of the G-coupled formyl peptide receptors[J]. Inflammation Research, 2000, 49(12), 744-755.
Authors:  Chen X.;  Yang D.;  Shen W.;  Dong H.F.;  Wang J.M.; et al.
Favorite | TC[WOS]:52 TC[Scopus]:52 | Submit date：2018/11/06
Bile Acids  Chemotaxis  Chenodeoxycholic Acid  Formyl Peptide Receptor  Formyl Peptide Receptor Like 1. Calcium Flux  
The N-formyl peptide receptor: A model for the study of chemoattractant receptor structure and function Journal article
Prossnitz E.R., Ye R.D.. The N-formyl peptide receptor: A model for the study of chemoattractant receptor structure and function[J]. Pharmacology and Therapeutics, 1997, 74(1), 73-102.
Authors:  Prossnitz E.R.;  Ye R.D.
Favorite | TC[WOS]:225 TC[Scopus]:230 | Submit date：2018/11/07
Chemoattractants  G-protein-coupled Receptor  Inflammation  N-formyl Peptide  N-formyl Peptide Receptor