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Covalent inhibition of epidermal growth factor receptor using a long-lived iridium(III)-afatinib probe Journal article
Nao, Sang Cuo, Kong, Lingtan, Chan, Daniel Shiu Hin, Liu, Jianhua, Huang, Le Sheng, Wu, Lei, Wu, Jia, Wong, Chun Yuen, Wang, Wanhe, Leung, Chung Hang. Covalent inhibition of epidermal growth factor receptor using a long-lived iridium(III)-afatinib probe[J]. International Journal of Biological Macromolecules, 2024, 259, 129211.
Authors:  Nao, Sang Cuo;  Kong, Lingtan;  Chan, Daniel Shiu Hin;  Liu, Jianhua;  Huang, Le Sheng; et al.
Favorite | TC[WOS]:2 TC[Scopus]:2  IF:7.7/7.7 | Submit date：2024/02/22
Afatinib Conjugate  Covalent Inhibitor  Egfr  Iridium Complex  Multifunctional Probe  
Epigallocatechin gallate circumvents drug induced resistance in non-small cell lung cancer by modulating glucose metabolism and AMPK/AKT/MAPK axis Journal article
Zhou, Yan, Huang, Shiqi, Guo, Yizhen, Ran, Maxoin, Shan, Wenying, Wen-Hau Chen, Tam, Kin Yip. Epigallocatechin gallate circumvents drug induced resistance in non-small cell lung cancer by modulating glucose metabolism and AMPK/AKT/MAPK axis[J]. Phytotheraphy Research, 2023, 37(12), 5837-5853.
Authors:  Zhou, Yan;  Huang, Shiqi;  Guo, Yizhen;  Ran, Maxoin;  Shan, Wenying; et al.
Favorite | TC[WOS]:6 TC[Scopus]:7  IF:6.1/7.0 | Submit date：2023/08/22
Acquired Drug Resistance  Combination Therapy  Egcg  Egfr-tkis  Nsclc  Synergetic Effect  
EGFR marks a subpopulation of dermal mesenchymal cells highly expressing IGF1 which enhances hair follicle regeneration Journal article
Chen, Min, Xu, Zaoxu, Chen, Yu, Yang, Qingyang, Lu, Ruiqing, Dong, Yankai, Li, Xiaosong, Xie, Jundong, Xu, Ren He, Jia, Haidong, Kang, Yan, Wu, Yaojiong. EGFR marks a subpopulation of dermal mesenchymal cells highly expressing IGF1 which enhances hair follicle regeneration[J]. Journal of Cellular and Molecular Medicine, 2023, 27(12), 1697-1707.
Authors:  Chen, Min;  Xu, Zaoxu;  Chen, Yu;  Yang, Qingyang;  Lu, Ruiqing; et al.
Favorite | TC[WOS]:2 TC[Scopus]:2  IF:4.3/5.0 | Submit date：2023/07/19
Cell Subpopulation  Egfr  Hair Follicle Regeneration  Igf1  Scrna-seq  
Down-regulating Nrf2 by tangeretin reverses multiple drug resistance to both chemotherapy and EGFR tyrosine kinase inhibitors in lung cancer Journal article
Xie Ying, Feng SenLing, He Fang, Yan PeiYu, Yao XiaoJun, Fan XingXing, Leung Elaine Lai Han, Zhou Hua. Down-regulating Nrf2 by tangeretin reverses multiple drug resistance to both chemotherapy and EGFR tyrosine kinase inhibitors in lung cancer[J]. PHARMACOLOGICAL RESEARCH, 2022, 186, 106514.
Authors:  Xie Ying;  Feng SenLing;  He Fang;  Yan PeiYu;  Yao XiaoJun; et al.
Favorite | TC[WOS]:15 TC[Scopus]:14  IF:9.1/9.0 | Submit date：2023/01/30
Drug Resistance  Chemotherapy  Egfr Tyrosine Kinase Inhibitors  Nrf2  Tangeretin  
CD47 blockade improves the therapeutic effect of osimertinib in non-small cell lung cancer Journal article
Wei-Bang Yu, Yu-Chi Chen,, Can-Yu Huang, Zi-Han Ye, Wei Shi, Hong Zhu, Jia-Jie Shi, Jun Chen, Jin-Jian Lu. CD47 blockade improves the therapeutic effect of osimertinib in non-small cell lung cancer[J]. Frontiers of Medicine, 2022, 17(1), 105-118.
Authors:  Wei-Bang Yu;  Yu-Chi Chen,;  Can-Yu Huang;  Zi-Han Ye;  Wei Shi; et al.
Favorite | TC[WOS]:2 TC[Scopus]:2  IF:3.9/5.4 | Submit date：2023/01/30
Adcp  Anti-cd47 Antibody  Combination Strategy  Egfr  Osimertinib  
Artesunate promoted anti-tumor immunity and overcame EGFR-TKI resistance in non-small-cell lung cancer by enhancing oncogenic TAZ degradation Journal article
Cao, Dai, Chen, Die, Xia, Jiang Nan, Wang, Wen Yan, Zhu, Guo Yuan, Chen, Li Wen, Zhang, Chuantao, Tan, Bo, Li, Hui, Li, Ying Wei. Artesunate promoted anti-tumor immunity and overcame EGFR-TKI resistance in non-small-cell lung cancer by enhancing oncogenic TAZ degradation[J]. Biomedicine and Pharmacotherapy, 2022, 155.
Authors:  Cao, Dai;  Chen, Die;  Xia, Jiang Nan;  Wang, Wen Yan;  Zhu, Guo Yuan; et al.
Favorite | TC[WOS]:10 TC[Scopus]:10  IF:6.9/6.8 | Submit date：2023/01/31
Anti-tumor Immunity  Artesunate  Egfr-tki Resistance  Non-small-cell Lung Cancer  Pd-l1  Taz  
Acetyltanshinone IIA reduces the synthesis of cell cycle-related proteins by degrading p70S6K and subsequently inhibits drug-resistant lung cancer cell growth Journal article
Huang, Bin, Hao, Meng, Li, Chuwen, Luo, Kathy Qian. Acetyltanshinone IIA reduces the synthesis of cell cycle-related proteins by degrading p70S6K and subsequently inhibits drug-resistant lung cancer cell growth[J]. Pharmacological Research, 2022, 179(106209), 1-18.
Authors:  Huang, Bin;  Hao, Meng;  Li, Chuwen;  Luo, Kathy Qian
Favorite | TC[WOS]:7 TC[Scopus]:7  IF:9.1/9.0 | Submit date：2022/05/13
Drug-resistant Lung Cancer  Acetyltanshinone Iia  Egfr  P70s6k  Aurora Kinase a  
An insulin growth factor-I/II-neutralizing monoclonal antibody in combination with epidermal growth factor receptor inhibitors potently inhibits tumor cell growth Journal article
Ma, Guofang, Tan, Chengyue, Shan, Yaming, Shao, Ningyi, Wang, Feng, Dimitrov, Dimiter S., Wang, Liping, Zhao, Qi. An insulin growth factor-I/II-neutralizing monoclonal antibody in combination with epidermal growth factor receptor inhibitors potently inhibits tumor cell growth[J]. Journal of Cancer, 2022, 13(5), 1830-1836.
Authors:  Ma, Guofang;  Tan, Chengyue;  Shan, Yaming;  Shao, Ningyi;  Wang, Feng; et al.
Favorite | TC[WOS]:4 TC[Scopus]:4  IF:3.3/3.3 | Submit date：2022/05/17
Egfr  Gefitinib  Igf-i  Igf-ii  M708.5  Monoclonal Antibody  
Proteome-wide Identification of Off-Targets of a Potent EGFRL858R/T790MMutant Inhibitor Journal article
Lyu, Peng, Jiang, Kaili, Zhou, Yuee, Hu, Jun, Chang, Yu, Zhang, Zhang, Huang, Minhao, Zhang, Zhi Min, Ding, Ke, Hao, Piliang, Lin, Ligen, Li, Zhengqiu. Proteome-wide Identification of Off-Targets of a Potent EGFRL858R/T790MMutant Inhibitor[J]. ACS Medicinal Chemistry Letters, 2022, 13(2), 292-297.
Authors:  Lyu, Peng;  Jiang, Kaili;  Zhou, Yuee;  Hu, Jun;  Chang, Yu; et al.
Favorite | TC[WOS]:3 TC[Scopus]:3  IF:3.5/3.9 | Submit date：2022/03/04
Egfr T790m  Chemoproteomics  Nt5dc1  Bioimaging  Target Identification  
Disruption of Epidermal Growth Factor Receptor but Not EGF Blocks Follicle Activation in Zebrafish Ovary Journal article
Yanlong Song, Weiting Chen, Bo Zhu, Wei Ge. Disruption of Epidermal Growth Factor Receptor but Not EGF Blocks Follicle Activation in Zebrafish Ovary[J]. FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2022, 9, 750888.
Authors:  Yanlong Song;  Weiting Chen;  Bo Zhu;  Wei Ge
Favorite | TC[WOS]:18 TC[Scopus]:19  IF:4.6/5.2 | Submit date：2022/02/21
Epidermal Growth Factor Egf  Egf Receptor Egfr  Gonadal Development  Folliculogenesis  Spermatogenesis  Zebrafish