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Sigma-1 receptor positive allosteric modulator promotes the neuronal survival and improves cognitive deficits in AD mice via Sigma-1 receptor/ERK pathway Conference paper
Xiaoyu Wang, Wenhua Zheng. Sigma-1 receptor positive allosteric modulator promotes the neuronal survival and improves cognitive deficits in AD mice via Sigma-1 receptor/ERK pathway[C], 2024.
Authors:  Xiaoyu Wang;  Wenhua Zheng
Favorite |  | Submit date：2024/08/31
Alzheimer's Disease, Somcl-668, Neuronal Cells, 3xtg-ad Mice, Sigma-1 Receptor/erk/creb Pathway  
Identification of Bulbocodin D and C as novel STAT3 inhibitors and their anticancer activities in lung cancer cells Journal article
HE, Xinyu, FU, Jiarui, LYU, Wenyu, HUANG, Muyang, MO, Jianshan, CHENG, Yaxin, XU, Yulian, ZHENG, Lijun, ZHANG, Xiaolei, QI, Lu, ZHANG, Lele, ZHENG, Ying, HUANG, Mingqing, NI, Lin, LU, Jinjian. Identification of Bulbocodin D and C as novel STAT3 inhibitors and their anticancer activities in lung cancer cells[J]. Chinese Journal of Natural Medicines, 2023, 21(11), 842-851.
Authors:  HE, Xinyu;  FU, Jiarui;  LYU, Wenyu;  HUANG, Muyang;  MO, Jianshan; et al.
Favorite | TC[WOS]:1 TC[Scopus]:1  IF:4.0/3.7 | Submit date：2024/01/10
Bulbocodin c  Bulbocodin d  Cancer  Erk  Natural Products  Stat3  
Targeting microglial autophagic degradation of the NLRP3 inflammasome for identification of thonningianin A in Alzheimer’s disease Journal article
Zhou, Xiao Gang, Qiu, Wen Qiao, Yu, Lu, Pan, Rong, Teng, Jin Feng, Sang, Zhi Pei, Law, Betty Yuen Kwan, Zhao, Ya, Zhang, Li, Yan, Lu, Tang, Yong, Sun, Xiao Lei, Wong, Vincent Kam Wai, Yu, Chong Lin, Wu, Jian Ming, Qin, Da Lian, Wu, An Guo. Targeting microglial autophagic degradation of the NLRP3 inflammasome for identification of thonningianin A in Alzheimer’s disease[J]. Inflammation and Regeneration, 2022, 42(1).
Authors:  Zhou, Xiao Gang;  Qiu, Wen Qiao;  Yu, Lu;  Pan, Rong;  Teng, Jin Feng; et al.
Favorite | TC[WOS]:23 TC[Scopus]:23  IF:5.0/7.2 | Submit date：2023/01/30
Alzheimer’s Disease  Ampk/ulk1  Autophagy  Nlrp3 Inflammasome  Raf/mek/erk  Thonningianin a  
Artemisinin attenuated ischemic stroke induced cell apoptosis through activation of ERK1/2/CREB/BCL-2 signaling pathway in vitro and in vivo Journal article
Tangming Peng, Shuai L, Linlin Liu, Chao Yang, Mohd Farhan, Ligang Chen, Qiaozhu Su, Zheng WH(鄭文華). Artemisinin attenuated ischemic stroke induced cell apoptosis through activation of ERK1/2/CREB/BCL-2 signaling pathway in vitro and in vivo[J]. International Journal of Biological Sciences, 2022, 2022(18(11)), 4578-4594.
Authors:  Tangming Peng;  Shuai L;  Linlin Liu;  Chao Yang;  Mohd Farhan; et al.
Favorite | TC[WOS]:36 TC[Scopus]:39  IF:8.2/8.3 | Submit date：2022/08/30
Ischemic Stroke  Artemisinin  Neuronal Damage  Erk1/2/creb/bcl-2  
Sinomenine inhibits macrophage M1 polarization by downregulating α7nAChR via a feedback pathway of α7nAChR/ERK/Egr-1 Journal article
Zhi, Ying kun, Li, Jing, Yi, Lang, Zhu, Rui li, Luo, Jin fang, Shi, Qing ping, Bai, Sha sha, Li, Yan wu, Du, Qun, Cai, Jia zhong, Liu, Liang, Wang, Pei xun, Zhou, Hua, Dong, Yan. Sinomenine inhibits macrophage M1 polarization by downregulating α7nAChR via a feedback pathway of α7nAChR/ERK/Egr-1[J]. Phytomedicine, 2022, 100.
Authors:  Zhi, Ying kun;  Li, Jing;  Yi, Lang;  Zhu, Rui li;  Luo, Jin fang; et al.
Favorite | TC[WOS]:14 TC[Scopus]:13  IF:6.7/6.2 | Submit date：2023/01/30
Erk/egr-1 Signaling Pathway  Inflammation  Macrophage Polarization  Sinomenine  Α7 Nicotinic Acetylcholine Receptor  
SPRC Suppresses Experimental Periodontitis by Modulating Th17/Treg Imbalance Journal article
Peng, Qian, Zhao, Bingkun, Lin, Jie, Liu, Haixia, Zhou, Rong, Lan, Dongmei, Yao, Chao, Cong, Shaohua, Tao, Shen, Zhu, Yizhun, Wang, Raorao, Qi, Shengcai. SPRC Suppresses Experimental Periodontitis by Modulating Th17/Treg Imbalance[J]. Frontiers in Bioengineering and Biotechnology, 2022, 9.
Authors:  Peng, Qian;  Zhao, Bingkun;  Lin, Jie;  Liu, Haixia;  Zhou, Rong; et al.
Favorite | TC[WOS]:11 TC[Scopus]:13  IF:4.3/5.1 | Submit date：2023/01/30
Erk/creb Signalling Pathway  Periodontitis  Regulatory t Cells  S-propargyl-cysteine  Th17 Cells  
Artemisinin attenuated ischemic stroke induced cell apoptosis through activation of ERK1/2/CREB/BCL-2 signaling pathway in vitro and in vivo Journal article
Peng, Tangming, Li, Shuai, Liu, Linlin, Yang, Chao, Farhan, Mohd, Chen, Ligang, Su, Qiaozhu, Zheng, Wenhua. Artemisinin attenuated ischemic stroke induced cell apoptosis through activation of ERK1/2/CREB/BCL-2 signaling pathway in vitro and in vivo[J]. International Journal of Biological Sciences, 2022, 18(11), 4578-4594.
Authors:  Peng, Tangming;  Li, Shuai;  Liu, Linlin;  Yang, Chao;  Farhan, Mohd; et al.
Favorite | TC[WOS]:36 TC[Scopus]:40  IF:8.2/8.3 | Submit date：2022/08/05
Artemisinin  Erk1/2/creb/bcl-2  Ischemic Stroke  Neuronal Damage  
Artemether conferred neuroprotection on cerebral ischemic injury through stimulating the ERK1/2/CREB signaling pathway Conference paper
Zheng, W.. Artemether conferred neuroprotection on cerebral ischemic injury through stimulating the ERK1/2/CREB signaling pathway[C], 2021.
Authors:  Zheng, W.
Favorite |  | Submit date：2022/08/31
Ischemic Stroke  Artemether  Mcao Model  Ogd  Erk1/2/creb  
Artemether conferred neuroprotection on cerebral ischemic injury through stimulating the ERK1/2/CREB signaling pathway Conference paper
Zheng, W.. Artemether conferred neuroprotection on cerebral ischemic injury through stimulating the ERK1/2/CREB signaling pathway[C], 2021.
Authors:  Zheng, W.
Favorite |  | Submit date：2022/08/31
Ischemic Stroke  Artemether  Middle Cerebral Artery Occlusion (Mcao)  Erk1/2/creb  
The neuroprotective effect of Art and their implication in thr treatment of cerebral ischemic stroke. Conference paper
Zheng, W.. The neuroprotective effect of Art and their implication in thr treatment of cerebral ischemic stroke.[C], 2021.
Authors:  Zheng, W.
Favorite |  | Submit date：2022/08/31
Ischemic Stroke  Artemether  Mcao Model  Ogd  Erk1/2/creb