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SSRI antidepressant citalopram reverses the Warburg effect to inhibit hepatocellular carcinoma by directly targeting GLUT1 Journal article
Dong, Fangyuan, He, Kang, Zhang, Shan, Song, Kaiyuan, Jiang, Luju, Hu, Li Peng, Li, Qing, Zhang, Xue Li, Zhang, Naiqi, Li, Bo Tai, Zhu, Li Li, Li, Jun, Feng, Mingxuan, Gao, Yunchen, Chen, Jie, Hu, Xiaona, Wang, Jiaofeng, Jiang, Chongyi, Wang, Cun, Zhu, Helen He, Da, Lin Tai, Ji, Jianguang, Zhang, Zhi Gang, Bao, Zhijun, Jiang, Shu Heng. SSRI antidepressant citalopram reverses the Warburg effect to inhibit hepatocellular carcinoma by directly targeting GLUT1[J]. Cell Reports, 2024, 43(10), 114818.
Authors:  Dong, Fangyuan;  He, Kang;  Zhang, Shan;  Song, Kaiyuan;  Jiang, Luju; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:7.5/8.5 | Submit date：2024/11/05
Aerobic Glycolysis  Drug Discovery  Drug Repurposing  Sert  Slc6a4  
Recent advances in bioaffinity strategies for preclinical and clinical drug discovery: Screening natural products, small molecules and antibodies Journal article
Jin, Haochun, Cui, Dianxin, Fan, Yu, Li, Guodong, Zhong, Zhangfeng, Wang, Yitao. Recent advances in bioaffinity strategies for preclinical and clinical drug discovery: Screening natural products, small molecules and antibodies[J]. Drug Discovery Today, 2024, 29(3), 103885.
Authors:  Jin, Haochun;  Cui, Dianxin;  Fan, Yu;  Li, Guodong;  Zhong, Zhangfeng; et al.
Favorite | TC[WOS]:5 TC[Scopus]:6  IF:6.5/7.3 | Submit date：2024/04/02
Antibodies  Bioaffinity Strategy  Drug Discovery  Natural Products  Small Molecule  
A deep learning method for predicting the minimum inhibitory concentration of antimicrobial peptides against Escherichia coli using Multi-Branch-CNN and Attention Review article
2023
Authors:  Yan, Jielu;  Zhang, Bob;  Zhou, Mingliang;  Campbell-Valois, François Xavier;  Siu, Shirley W.I.
Favorite | TC[WOS]:3 TC[Scopus]:5  IF:5.0/6.1 | Submit date：2024/01/02
Antimicrobial Peptides  Deep Learning  Drug Discovery  Minimum Inhibitory Concentrations  Regression  
Editorial: Regulation of PI3K/Akt signaling pathway: A feasible approach for natural neuroprotective agents to treat various neuron injury-related diseases Other
2023-02-01
Authors:  Chen, Yunhui;  Hsu, Charles;  Chen, Xiuping;  Zhang, Heng;  Peng, Wei
Favorite | TC[WOS]:3 TC[Scopus]:2 | Submit date：2023/03/06
Drug Discovery  Natural Agents  Neuron Injury  Neuroprotective Effect  Pi3k/akt  
Recent advances in organotypic tissue slice cultures for anticancer drug development Review article
2022
Authors:  He, Lin;  Deng, Chuxia
Favorite | TC[WOS]:16 TC[Scopus]:17  IF:8.2/8.3 | Submit date：2023/01/30
Anticancer Drug Discovery  Individualized Treatment  Organotypic Tissue Slice Culture  Precision Oncology  
Multi-Branch-CNN: Classification of ion channel interacting peptides using multi-branch convolutional neural network Journal article
Yan, Jielu, Zhang, Bob, Zhou, Mingliang, Kwok, Hang Fai, Siu, Shirley W.I.. Multi-Branch-CNN: Classification of ion channel interacting peptides using multi-branch convolutional neural network[J]. Computers in Biology and Medicine, 2022, 147, 105717.
Authors:  Yan, Jielu;  Zhang, Bob;  Zhou, Mingliang;  Kwok, Hang Fai;  Siu, Shirley W.I.
Favorite | TC[WOS]:13 TC[Scopus]:14  IF:7.0/6.7 | Submit date：2022/08/01
Classification  Deep Learning  Drug Discovery  Ion Channel  Multi-branch-cnn  Peptides  
Editorial: Insights in Protein Chemistry and Enzymology: 2021 Other
2022-06-20
Authors:  Kwok, Hang Fai;  Zhang, Qi
Favorite | TC[WOS]:0 TC[Scopus]:0 | Submit date：2022/08/01
Drug Discovery  Enzymology Characterization  Inhibitor  Protein Chemistry Design And Folding  Proteomic Analyses  Structural Biology  
Proteases -- From Basic Structure to Function to Drug Design as Targeted Therapy Book
Kwok, H. F., Shaw, C., Walker, B.. Proteases -- From Basic Structure to Function to Drug Design as Targeted Therapy[M]. Switzerland:MDPI, 2021.
Authors:  Kwok, H. F.;  Shaw, C.;  Walker, B.
Favorite |  | Submit date：2022/06/14
Protease inhibitor  Drug discovery  Mode of actions  
Ubiquitination Regulators Discovered by Virtual Screening for the Treatment of Cancer Review article
2021
Authors:  Song, Ying Qi;  Wu, Chun;  Wu, Ke Jia;  Han, Quan Bin;  Miao, Xiang Min; et al.
Favorite | TC[WOS]:5 TC[Scopus]:5  IF:4.6/5.2 | Submit date：2021/12/07
Ubiquitination Regulator  Virtual Screening  Drug Discovery  Cancer  Treatment  
Natural Products in Cancer Therapy: Past, Present and Future Journal article
Huang,Min, Lu,Jin Jian, Ding,Jian. Natural Products in Cancer Therapy: Past, Present and Future[J]. Natural Products and Bioprospecting, 2021, 11(1), 5-13.
Authors:  Huang,Min;  Lu,Jin Jian;  Ding,Jian
Favorite | TC[WOS]:323 TC[Scopus]:333  IF:4.8/3.9 | Submit date：2021/03/02
Antibody–drug Conjugates  Cancer Therapy  Combination Therapy  Drug Discovery  Natural Products