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Activation of the PERK/eIF2α axis is a pivotal prerequisite of taxanes to cancer cell apoptosis and renders synergism to overcome paclitaxel resistance in breast cancer cells Journal article
Cai, Wanhua, Rong, Dade, Ding, Jiayu, Zhang, Xiaomei, Wang, Yuwei, Fang, Ying, Xiao, Jing, Yang, Shulan, Wang, Haihe. Activation of the PERK/eIF2α axis is a pivotal prerequisite of taxanes to cancer cell apoptosis and renders synergism to overcome paclitaxel resistance in breast cancer cells[J]. Cancer Cell International, 2024, 24(1), 249.
Authors:  Cai, Wanhua;  Rong, Dade;  Ding, Jiayu;  Zhang, Xiaomei;  Wang, Yuwei; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:5.3/5.0 | Submit date：2024/08/05
Breast Cancer  Er Stress  Perk/eif2α  Taxane  Tumor Drug Resistance  
Nanoenabled intracellular zinc bursting for efficacious reversal of gefitinib resistance in lung cancer Journal article
Li, Junnan, Assaraf, Yehuda G., Zuo, Weimin, Lin, Ziqi, Leong, Ka Weng, Zhao, Qi, Zhu, Lipeng, Kwok, Hang Fai. Nanoenabled intracellular zinc bursting for efficacious reversal of gefitinib resistance in lung cancer[J]. International Journal of Biological Sciences, 2024, 20(8), 3028-3045.
Authors:  Li, Junnan;  Assaraf, Yehuda G.;  Zuo, Weimin;  Lin, Ziqi;  Leong, Ka Weng; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:8.2/8.3 | Submit date：2024/07/04
Cancer Therapy  Drug Resistance  Lung Cancer  Reactive Oxygen Species (Ros)  Zeolitic Imidazolate Framework-8 (Zif-8)  Zn2++++  
Fighting drug-resistant lung cancer by induction of NAD(P)H:quinone oxidoreductase 1 (NQO1)-mediated ferroptosis Journal article
Yu,Jie, Zhong,Bingling, Zhao,Lin, Hou,Ying, Ai,Nana, Lu,Jin Jian, Ge,Wei, Chen,Xiuping. Fighting drug-resistant lung cancer by induction of NAD(P)H:quinone oxidoreductase 1 (NQO1)-mediated ferroptosis[J]. Drug Resistance Updates, 2023, 70, 100977.
Authors:  Yu,Jie;  Zhong,Bingling;  Zhao,Lin;  Hou,Ying;  Ai,Nana; et al.
Favorite | TC[WOS]:27 TC[Scopus]:28  IF:15.8/18.1 | Submit date：2023/08/03
Drug-resistance  Ferroptosis  Lung Cancer  Mam  Nqo1  
High Levels of Antibiotic Resistance in MDR-Strong Biofilm-Forming Salmonella Typhimurium ST34 in Southern China Journal article
Gao, Yuan, Chen, Kaifeng, Lin, Runshan, Xu, Xuebin, Xu, Fengxiang, Lin, Qijie, Hu, Yaping, Zhang, Hongxia, Zhang, Jianmin, Liao, Ming, Qu, Xiaoyun. High Levels of Antibiotic Resistance in MDR-Strong Biofilm-Forming Salmonella Typhimurium ST34 in Southern China[J]. Microorganisms, 2023, 11(8), 2005.
Authors:  Gao, Yuan;  Chen, Kaifeng;  Lin, Runshan;  Xu, Xuebin;  Xu, Fengxiang; et al.
Favorite | TC[WOS]:1 TC[Scopus]:1  IF:4.1/4.5 | Submit date：2023/09/04
Acssut  Biofilm  Drug Resistance  S. typhimurium  St34  
Epigallocatechin gallate circumvents drug induced resistance in non-small cell lung cancer by modulating glucose metabolism and AMPK/AKT/MAPK axis Journal article
Zhou, Yan, Huang, Shiqi, Guo, Yizhen, Ran, Maxoin, Shan, Wenying, Wen-Hau Chen, Tam, Kin Yip. Epigallocatechin gallate circumvents drug induced resistance in non-small cell lung cancer by modulating glucose metabolism and AMPK/AKT/MAPK axis[J]. Phytotheraphy Research, 2023, 37(12), 5837-5853.
Authors:  Zhou, Yan;  Huang, Shiqi;  Guo, Yizhen;  Ran, Maxoin;  Shan, Wenying; et al.
Favorite | TC[WOS]:6 TC[Scopus]:7  IF:6.1/7.0 | Submit date：2023/08/22
Acquired Drug Resistance  Combination Therapy  Egcg  Egfr-tkis  Nsclc  Synergetic Effect  
Repurposing the Hedgehog pathway inhibitor, BMS-833923, as a phosphatidylglycerol-selective membrane-disruptive colistin adjuvant against ESKAPE pathogens Journal article
Zhang,Nian, Shan,Wenying, Gao,Liangliang, Kou,Si Hoi, Lu,Chang, Yang,Huilin, Peng,Bo, Tam,Kin Yip, Lee,Leo Tsz On, Zheng,Jun. Repurposing the Hedgehog pathway inhibitor, BMS-833923, as a phosphatidylglycerol-selective membrane-disruptive colistin adjuvant against ESKAPE pathogens[J]. International Journal of Antimicrobial Agents, 2023, 62(3), 106888.
Authors:  Zhang,Nian;  Shan,Wenying;  Gao,Liangliang;  Kou,Si Hoi;  Lu,Chang; et al.
Favorite | TC[WOS]:4 TC[Scopus]:4  IF:4.9/5.6 | Submit date：2023/08/03
Antibiotic Resistance  Colistin Adjuvant  Drug Repurposing  Eskape  Membrane-disruptive Drug  
The role and prospect of lysine-specific demethylases in cancer chemoresistance Journal article
Ying-Qi Song, Guan-Jun Yang, Dik-Lung Ma, Wanhe Wang, Chung-Hang Leung. The role and prospect of lysine-specific demethylases in cancer chemoresistance[J]. Medicinal Research Reviews, 2023, 43(5), 1438-1469.
Authors:  Ying-Qi Song;  Guan-Jun Yang;  Dik-Lung Ma;  Wanhe Wang;  Chung-Hang Leung
Favorite | TC[WOS]:10 TC[Scopus]:10  IF:10.9/12.9 | Submit date：2023/08/03
Cancer  Drug Resistance  Epigenetics  Inhibitor  Lysine-specific Demethylases  
Editorial: New mechanistic insights into cancer precision medicine Other
2023-02-16
Authors:  Kwok,Hang Fai
Favorite | TC[WOS]:0 TC[Scopus]:0 | Submit date：2023/08/03
Immunotherapy  Targeted Therapy  Therapeutic Antibody  Chemotherapy  Novel Bioactive Molecule  Biomarker  Drug Resistance  
Multiple initiatives to conquer KRAS G12C inhibitor resistance from the perspective of clinical therapy Journal article
Zhang JunMin, Zhang JuanHong, Leung Elaine Lai Han, Yao XiaoJun. Multiple initiatives to conquer KRAS G12C inhibitor resistance from the perspective of clinical therapy[J]. EXPERT OPINION ON INVESTIGATIONAL DRUGS, 2023, 32(2), 101-106.
Authors:  Zhang JunMin;  Zhang JuanHong;  Leung Elaine Lai Han;  Yao XiaoJun
Favorite | TC[WOS]:2 TC[Scopus]:2  IF:4.9/5.3 | Submit date：2023/06/15
Kras G12c  Amg 510  Mrtx 849  Targeted Therapy  Drug Resistance  
Metabolic modulation of CtBP dimeric status impacts the repression of DNA damage repair genes and the platinum sensitivity of ovarian cancer Journal article
Li,Jingjing, Wang,Yuan, Wang,Li, Hao,Dapeng, Li,Peipei, Su,Minxia, Zhao,Zhiqiang, Liu,Tianyu, Tai,Lixin, Lu,Jinjian, Di,Li Jun. Metabolic modulation of CtBP dimeric status impacts the repression of DNA damage repair genes and the platinum sensitivity of ovarian cancer[J]. International journal of biological sciences, 2023, 19(7), 2081-2096.
Authors:  Li,Jingjing;  Wang,Yuan;  Wang,Li;  Hao,Dapeng;  Li,Peipei; et al.
Favorite | TC[WOS]:2 TC[Scopus]:2  IF:8.2/8.3 | Submit date：2023/08/03
Cisplatin  Ctbp  Drug Resistance  Metformin  Ovarian Cancer