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Pathogenic variants in human DNA damage repair genes mostly arose in recent human history Journal article
Zhao, Bojin, Li, Jiaheng, Sinha, Siddharth, Qin, Zixin, Kou, Si Hoi, Xiao, Fengxia, Lei, Huijun, Chen, Tianhui, Cao, Wenming, Ding, Xiaofan, Wang, San Ming. Pathogenic variants in human DNA damage repair genes mostly arose in recent human history[J]. BMC Cancer, 2024, 24(1), 415.
Authors:  Zhao, Bojin;  Li, Jiaheng;  Sinha, Siddharth;  Qin, Zixin;  Kou, Si Hoi; et al.
Favorite | TC[WOS]:3 TC[Scopus]:3  IF:3.4/3.8 | Submit date：2024/05/16
Archaeological  Dna Damage Repair  Evolutionary Origin  Pathogenic Variants  Phylogenetic  
Heterozygotic Brca1 mutation initiates mouse genome instability at embryonic stage Journal article
Wu, Xiaobing, Guo, Maoni, Cui, Jian, Cai, Haoyang, Wang, San Ming. Heterozygotic Brca1 mutation initiates mouse genome instability at embryonic stage[J]. Oncogenesis, 2022, 11(1), 41.
Authors:  Wu, Xiaobing;  Guo, Maoni;  Cui, Jian;  Cai, Haoyang;  Wang, San Ming
Favorite | TC[WOS]:4 TC[Scopus]:4  IF:5.9/6.0 | Submit date：2022/08/02
Homologous Recombination  Cancer Susceptibility  Breast-cancer  Dna-damage  Deficiency  Repair  End  Amplification  Association  Expression  
ceRNA Networks: The Backbone Role in Neoadjuvant Chemoradiotherapy Resistance/Sensitivity of Locally Advanced Rectal Cancer Review article
2021
Authors:  Lin He;  Hao Chang;  Yuhong Qi;  Bing Zhang;  Qiuju Shao
Favorite | TC[WOS]:3 TC[Scopus]:3  IF:2.7/2.8 | Submit date：2022/05/13
Neoadjuvant Chemoradiotherapy  Dna Damage Repair  Locally Advanced Rectal Cancer  Competing Endogenous Rnas  
DNA damage repair system in C57BL/6J mice is evolutionarily stable Journal article
Wang, Xiaoyu, Wang, San Ming. DNA damage repair system in C57BL/6J mice is evolutionarily stable[J]. BMC Genomics, 2021, 22(1), 669.
Authors:  Wang, Xiaoyu;  Wang, San Ming
Favorite | TC[WOS]:1 TC[Scopus]:1  IF:3.5/4.1 | Submit date：2022/07/27
Brca1  Brca2  Dna Damage Repair  C57bl/6j  Variation  Evolution Selection  6 j  
DNA damage repair system in C57BL/6 J mice is evolutionarily stable Journal article
Wang, Xiaoyu, Wang, San Ming. DNA damage repair system in C57BL/6 J mice is evolutionarily stable[J]. BMC Genomics, 2021, 22(1), 669.
Authors:  Wang, Xiaoyu;  Wang, San Ming
Favorite | TC[WOS]:1 TC[Scopus]:1  IF:3.5/4.1 | Submit date：2021/12/08
Brca1  Brca2  C57bl/6 j  Dna Damage Repair  Evolution Selection  Variation  6 j  
Can population BRCA screening be applied in non-Ashkenazi Jewish populations? Experience in Macau population Journal article
Qin, Zixin, Kuok, Cheong Nang, Dong, Hui, Jiang, Luhan, Zhang, Li, Guo, Maoni, Leong, Hio Kuan, Wang, Lei, Meng, Grace, Wang, San Ming. Can population BRCA screening be applied in non-Ashkenazi Jewish populations? Experience in Macau population[J]. JOURNAL OF MEDICAL GENETICS, 2021, 58(9), 587-591.
Authors:  Qin, Zixin;  Kuok, Cheong Nang;  Dong, Hui;  Jiang, Luhan;  Zhang, Li; et al.
Favorite | TC[WOS]:9 TC[Scopus]:13  IF:3.5/4.1 | Submit date：2021/12/08
Dna Damage  Dna Repair  Early Diagnosis  Genetic Carrier Screening  Genetics  
Genomic and Molecular Landscape of DNA Damage Repair Deficiency across The Cancer Genome Atlas Journal article
Knijnenburg T.A., Wang L., Zimmermann M.T., Chambwe N., Gao G.F., Cherniack A.D., Fan H., Shen H., Way G.P., Greene C.S., Liu Y., Akbani R., Feng B., Donehower L.A., Miller C., Shen Y., Karimi M., Chen H., Kim P., Jia P., Shinbrot E., Zhang S., Liu J., Hu H., Bailey M.H., Yau C., Wolf D., Zhao Z., Weinstein J.N., Li L., Ding L., Mills G.B., Laird P.W., Wheeler D.A., Shmulevich I., Caesar-Johnson S.J., Demchok J.A., Felau I., Kasapi M., Ferguson M.L., Hutter C.M., Sofia H.J., Tarnuzzer R., Wang Z., Yang L., Zenklusen J.C., Zhang J.J., Chudamani S., Lolla L., Naresh R., Pihl T., Sun Q., Wan Y., Wu Y., Cho J., DeFreitas T., Frazer S., Gehlenborg N., Getz G., Heiman D.I., Kim J., Lawrence M.S., Lin P., Meier S., Noble M.S., Saksena G., Voet D., Zhang H., Bernard B., Dhankani V., Knijnenburg T., Kramer R., Leinonen K., Miller M., Reynolds S., Thorsson V., Zhang W., Broom B.M., Hegde A.M., Ju Z., Kanchi R.S., Korkut A., Li J., Liang H., Ling S., Liu W., Lu Y., Ng K.-S., Rao A., Ryan M., Wang J., Zhang J., Abeshouse A., Armenia J., Chakravarty D., Chatila W.K., de Bruijn I., Gao J., Gross B.E., Heins Z.J., Kundra R., La K., Ladanyi M., Luna A., Nissan M.G., Ochoa A., Phillips S.M., Reznik E., Sanchez-Vega F., Sander C., Schultz N., Sheridan R., Sumer S.O., Sun Y., Taylor B.S., Anur P., Peto M., Spellman P., Benz C., Stuart J.M., Wong C.K., Hayes D.N., Parker J.S., Wilkerson M.D., Ally A., Balasundaram M., Bowlby R., Brooks D., Carlsen R., Chuah E., Dhalla N., Holt R., Jones S.J.M., Kasaian K., Lee D., Ma Y., Marra M.A., Mayo M., Moore R.A., Mungall A.J., Mungall K., Robertson A.G., Sadeghi S., Schein J.E., Sipahimalani P., Tam A., Thiessen N., Tse K., Wong T., Berger A.C., Beroukhim R., Cibulskis C., Gabriel S.B., Ha G., Meyerson M., Schumacher S.E., Shih J., Kucherlapati M.H., Kucherlapati R.S., Baylin S., Cope L., Danilova L., Bootwalla M.S., Lai P.H., Maglinte D.T., Van Den Berg D.J., Weisenberger D.J., Auman J.T., Balu S., Bodenheimer T., Fan C., Hoadley K.A., Hoyle A.P., Jefferys S.R., Jones C.D., Meng S., Mieczkowski P.A., Mose L.E., Perou A.H., Perou C.M., Roach J., Shi Y., Simons J.V., Skelly T., Soloway M.G., Tan D., Veluvolu U., Hinoue T., Zhou W., Bellair M., Chang K., Covington K., Creighton C.J., Dinh H., Doddapaneni H., Drummond J., Gibbs R.A., Glenn R., Hale W., Han Y., Hu J., Korchina V., Lee S., Lewis L., Li W., Liu X., Morgan M., Morton D., Muzny D., Santibanez J., Sheth M., Wang M., Xi L., Zhao F., Hess J., Appelbaum E.L., Bailey M., Cordes M.G., Fronick C.C., Fulton L.A., Fulton R.S., Kandoth C., Mardis E.R., McLellan M.D., Miller C.A., Schmidt H.K., Wilson R.K., Crain D., Curley E., Gardner J., Lau K., Mallery D., Morris S., Paulauskis J., Penny R., Shelton C., Shelton T., Sherman M., Thompson E., Yena P., Bowen J., Gastier-Foster J.M., Gerken M., Leraas K.M., Lichtenberg T.M., Ramirez N.C., Wise L., Zmuda E., Corcoran N., Costello T., Hovens C., Carvalho A.L., de Carvalho A.C., Fregnani J.H., Longatto-Filho A., Reis R.M., Scapulatempo-Neto C., Silveira H.C.S., Vidal D.O., Burnette A., Eschbacher J., Hermes B., Noss A., Singh R., Anderson M.L., Castro P.D., Ittmann M., Huntsman D., Kohl B., Le X., Thorp R., Andry C., Duffy E.R., Lyadov V., Paklina O., Setdikova G., Shabunin A., Tavobilov M., McPherson C., Warnick R., Berkowitz R., Cramer D., Feltmate C., Horowitz N., Kibel A., Muto M., Raut C.P., Malykh A., Barnholtz-Sloan J.S., Barrett W., Devine K., Fulop J., Ostrom Q.T., Shimmel K., Wolinsky Y., Sloan A.E., De Rose A., Giuliante F., Goodman M., Karlan B.Y., Hagedorn C.H., Eckman J., Harr J., Myers J., Tucker K., Zach L.A., Deyarmin B., Kvecher L., Larson C., Mural R.J., Somiari S., Vicha A., Zelinka T., Bennett J., Iacocca M., Rabeno B., Swanson P., Latour M., Lacombe L., Tetu B., Bergeron A., McGraw M., Staugaitis S.M., Chabot J., Hibshoosh H., Sepulveda A., Su T., Wang T., Potapova O., Voronina O., Desjardins L., Mariani O., Roman-Roman S., Sastre X., Stern M.-H., Cheng F., Signoretti S., Berchuck A., Bigner D., Lipp E., Marks J., McCall S., McLendon R., Secord A., Sharp A., Behera M., Brat D.J., Chen A., Delman K., Force S., Khuri F., Magliocca K., Maithel S., Olson J.J., Owonikoko T., Pickens A., Ramalingam S., Shin D.M., Sica G., Van Meir E.G., Zhang H., Eijckenboom W., Gillis A., Korpershoek E., Looijenga L., Oosterhuis W., Stoop H., van Kessel K.E., Zwarthoff E.C., Calatozzolo C., Cuppini L., Cuzzubbo S., DiMeco F., Finocchiaro G., Mattei L., Perin A., Pollo B., Chen C., Houck J., Lohavanichbutr P., Hartmann A., Stoehr C., Stoehr R., Taubert H., Wach S., Wullich B., Kycler W., Murawa D., Wiznerowicz M., Chung K., Edenfield W.J., Martin J., Baudin E., Bubley G., Bueno R., De Rienzo A., Richards W.G., Kalkanis S., Mikkelsen T., Noushmehr H., Scarpace L., Girard N., Aymerich M., Campo E., Gine E., Guillermo A.L., Van Bang N., Hanh P.T., Phu B.D., Tang Y., Colman H., Evason K., Dottino P.R., Martignetti J.A., Gabra H., Juhl H., Akeredolu T., Stepa S., Hoon D., Ahn K., Kang K.J., Beuschlein F., Breggia A., Birrer M., Bell D., Borad M., Bryce A.H., Castle E., Chandan V., Cheville J., Copland J.A., Farnell M., Flotte T., Giama N., Ho T., Kendrick M., Kocher J.-P., Kopp K., Moser C., Nagorney D., O'Brien D., O'Neill B.P., Patel T., Petersen G., Que F., Rivera M., Roberts L., Smallridge R., Smyrk T., Stanton M., Thompson R.H., Torbenson M., Yang J.D., Zhang L., Brimo F., Ajani J.A., Gonzalez A.M.A., Behrens C., Bondaruk J., Broaddus R., Czerniak B., Esmaeli B., Fujimoto J., Gershenwald J., Guo C., Lazar A.J., Logothetis C., Meric-Bernstam F., Moran C., Ramondetta L., Rice D., Sood A., Tamboli P., Thompson T., Troncoso P., Tsao A., Wistuba I., Carter C., Haydu L., Hersey P., Jakrot V., Kakavand H., Kefford R., Lee K., Long G., Mann G., Quinn M., Saw R., Scolyer R., Shannon K., Spillane A., Stretch J., Synott M., Thompson J., Wilmott J., Al-Ahmadie H., Chan T.A., Ghossein R., Gopalan A., Levine D.A., Reuter V., Singer S., Singh B., Tien N.V., Broudy T., Mirsaidi C., Nair P., Drwiega P., Miller J., Smith J., Zaren H., Park J.-W., Hung N.P., Kebebew E., Linehan W.M., Metwalli A.R., Pacak K., Pinto P.A., Schiffman M., Schmidt L.S., Vocke C.D., Wentzensen N., Worrell R., Yang H., Moncrieff M., Goparaju C., Melamed J., Pass H., Botnariuc N., Caraman I., Cernat M., Chemencedji I., Clipca A., Doruc S., Gorincioi G., Mura S., Pirtac M., Stancul I., Tcaciuc D., Albert M., Alexopoulou I., Arnaout A., Bartlett J., Engel J., Gilbert S., Parfitt J., Sekhon H., Thomas G., Rassl D.M., Rintoul R.C., Bifulco C., Tamakawa R., Urba W., Hayward N., Timmers H., Antenucci A., Facciolo F., Grazi G., Marino M., Merola R., de Krijger R., Gimenez-Roqueplo A.-P., Piche A., Chevalier S., McKercher G., Birsoy K., Barnett G., Brewer C., Farver C., Naska T., Pennell N.A., Raymond D., Schilero C., Smolenski K., Williams F., Morrison C., Borgia J.A., Liptay M.J., Pool M., Seder C.W., Junker K., Omberg L., Dinkin M., Manikhas G., Alvaro D., Bragazzi M.C., Cardinale V., Carpino G., Gaudio E., Chesla D., Cottingham S., Dubina M., Moiseenko F., Dhanasekaran R., Becker K.-F., Janssen K.-P., Slotta-Huspenina J., Abdel-Rahman M.H., Aziz D., Bell S., Cebulla C.M., Davis A., Duell R., Elder J.B., Hilty J., Kumar B., Lang J., Lehman N.L., Mandt R., Nguyen P., Pilarski R., Rai K., Schoenfield L., Senecal K., Wakely P., Hansen P., Lechan R., Powers J., Tischler A., Grizzle W.E., Sexton K.C., Kastl A., Henderson J., Porten S., Waldmann J., Fassnacht M., Asa S.L., Schadendorf D., Couce M., Graefen M., Huland H., Sauter G., Schlomm T., Simon R., Tennstedt P., Olabode O., Nelson M., Bathe O., Carroll P.R., Chan J.M., Disaia P., Glenn P., Kelley R.K., Landen C.N., Phillips J., Prados M., Simko J., Smith-McCune K., VandenBerg S., Roggin K., Fehrenbach A., Kendler A., Sifri S., Steele R., Jimeno A., Carey F., Forgie I., Mannelli M., Carney M., Hernandez B., Campos B., Herold-Mende C., Jungk C., Unterberg A., von Deimling A., Bossler A., Galbraith J., Jacobus L., Knudson M., Knutson T., Ma D., Milhem M., Sigmund R., Godwin A.K., Madan R., Rosenthal H.G., Adebamowo C., Adebamowo S.N., Boussioutas A., Beer D., Giordano T., Mes-Masson A.-M., Saad F., Bocklage T., Landrum L., Mannel R., Moore K., Moxley K., Postier R., Walker J., Zuna R., Feldman M., Valdivieso F., Dhir R., Luketich J., Pinero E.M.M., Quintero-Aguilo M., Carlotti C.G., Dos Santos J.S., Kemp R., Sankarankuty A., Tirapelli D., Catto J., Agnew K., Swisher E., Creaney J., Robinson B., Shelley C.S., Godwin E.M., Kendall S., Shipman C., Bradford C., Carey T., Haddad A., Moyer J., Peterson L., Prince M., Rozek L., Wolf G., Bowman R., Fong K.M., Yang I., Korst R., Rathmell W.K., Fantacone-Campbell J.L., Hooke J.A., Kovatich A.J., Shriver C.D., DiPersio J., Drake B., Govindan R., Heath S., Ley T., Van Tine B., Westervelt P., Rubin M.A., Lee J.I., Aredes N.D., Mariamidze A., Monnat R.J., Xiao Y., Wang C.. Genomic and Molecular Landscape of DNA Damage Repair Deficiency across The Cancer Genome Atlas[J]. Cell Reports, 2018, 23(1), 239-254.e6.
Authors:  Knijnenburg T.A.;  Wang L.;  Zimmermann M.T.;  Chambwe N.;  Gao G.F.; et al.
Favorite | TC[WOS]:709 TC[Scopus]:719 | Submit date：2019/01/16
Dna Damage Footprints  Dna Damage Repair  Epigenetic Silencing  Integrative Statistical Analysis  Mutational Signatures  Protein Structure Analysis  Somatic Copy-number Alterations  Somatic Mutations  The Cancer Genome Atlas pancanAtlas Project