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Combined use of arginase and dichloroacetate exhibits anti-proliferative effects in triple negative breast cancer cells Journal article
Angela Verma, Yau-Min Lam, Yun-Chung Leung, Xiaohui Hu, Xin Chen, Edwin Cheung, Kin Yip Tam. Combined use of arginase and dichloroacetate exhibits anti-proliferative effects in triple negative breast cancer cells[J]. JOURNAL OF PHARMACY AND PHARMACOLOGY, 2019, 71(3), 306-315.
Authors:  Angela Verma;  Yau-Min Lam;  Yun-Chung Leung;  Xiaohui Hu;  Xin Chen; et al.
Favorite | TC[WOS]:18 TC[Scopus]:18  IF:2.8/3.8 | Submit date：2020/05/21
Bacillus Caldovelox Arginase  Breast Cancer  Dichloroacetate  Drug Combination  Pegyated Human Arginase  
Liquid Chromatography-Tandem Mass Spectrometry Method Revealed that Lung Cancer Cells Exhibited Distinct Metabolite Profiles upon the Treatment with Different Pyruvate Dehydrogenase Kinase Inhibitors Journal article
Zhang, Wen, Hu, Xiaohui, Zhou, Wei, Tam, Kin Yip. Liquid Chromatography-Tandem Mass Spectrometry Method Revealed that Lung Cancer Cells Exhibited Distinct Metabolite Profiles upon the Treatment with Different Pyruvate Dehydrogenase Kinase Inhibitors[J]. JOURNAL OF PROTEOME RESEARCH, 2018, 17(9), 3012-3021.
Authors:  Zhang, Wen;  Hu, Xiaohui;  Zhou, Wei;  Tam, Kin Yip
Favorite | TC[WOS]:18 TC[Scopus]:18  IF:3.8/4.1 | Submit date：2018/10/30
Aerobic Glycolysis  Azd7545  Dichloroacetate  Lc-ms/ms  Pyruvate Dehydrogenase Kinases  Cancer Metabolism  
Liquid Chromatography–Tandem Mass Spectrometry Method Revealed that Lung Cancer Cells Exhibited Distinct Metabolite Profiles upon the Treatment with Different Pyruvate Dehydrogenase Kinase Inhibitors Journal article
Zhang, W., Hu, X., Zhou, W., Tam, K. Y.. Liquid Chromatography–Tandem Mass Spectrometry Method Revealed that Lung Cancer Cells Exhibited Distinct Metabolite Profiles upon the Treatment with Different Pyruvate Dehydrogenase Kinase Inhibitors[J]. Journal of Proteome Research, 2018, 1-10.
Authors:  Zhang, W.;  Hu, X.;  Zhou, W.;  Tam, K. Y.
Favorite | TC[WOS]:18 TC[Scopus]:18  IF:3.8/4.1 | Submit date：2022/07/28
Aerobic Glycolysis  Azd7545  Cancer Metabolism  Dichloroacetate  Lc−ms/ms  Pyruvate Dehydrogenase Kinases  
Pharmacological synergism of 2,2-dichloroacetophenone and EGFR-TKi to overcome TKi-induced resistance in NSCLC cells Journal article
Yang, Zheng, Hu, Xiaohui, Zhang, Shaolin, Zhang, Wen, Tam, Kin Yip. Pharmacological synergism of 2,2-dichloroacetophenone and EGFR-TKi to overcome TKi-induced resistance in NSCLC cells[J]. EUROPEAN JOURNAL OF PHARMACOLOGY, 2017, 815, 80-87.
Authors:  Yang, Zheng;  Hu, Xiaohui;  Zhang, Shaolin;  Zhang, Wen;  Tam, Kin Yip
Favorite | TC[WOS]:14 TC[Scopus]:14  IF:4.2/4.3 | Submit date：2018/10/30
Synergism  Dichloroacetophenone  Dichloroacetate  Egfr  Apoptosis  Acquired Resistance  
Unexpected Discovery of Dichloroacetate Derived AdenosineTriphosphate Competitors Targeting Pyruvate DehydrogenaseKinase To Inhibit Cancer Proliferation Journal article
Zhang, S.L., Hu, X., Zhang, W., Tam, K. Y.. Unexpected Discovery of Dichloroacetate Derived AdenosineTriphosphate Competitors Targeting Pyruvate DehydrogenaseKinase To Inhibit Cancer Proliferation[J]. Jourma of Medicinal Chemistry, 2016, 3562-3568.
Authors:  Zhang, S.L.;  Hu, X.;  Zhang, W.;  Tam, K. Y.
Favorite | TC[WOS]:44 TC[Scopus]:46  IF:6.8/7.1 | Submit date：2022/07/28
Pyruvate Dehydrogenase Kinase  Pyruvate Dehydrogenase Complex  Atp Binding Pocket  Pyruvate Binding Pocket  Dichloroacetate Sodium  
Anti-cancer synergy of dichloroacetate and EGFR tyrosine kinase inhibitors in NSCLC cell lines Journal article
Yang Z., Tam K.Y.. Anti-cancer synergy of dichloroacetate and EGFR tyrosine kinase inhibitors in NSCLC cell lines[J]. European Journal of Pharmacology, 2016, 789, 458-467.
Authors:  Yang Z.;  Tam K.Y.
Favorite | TC[WOS]:31 TC[Scopus]:31 | Submit date：2018/12/18
Dichloroacetate  Drug Combination  Epidermal Growth Factor Receptor  Erlotinib  Gefitinib  Pyruvate Dehydrogenase Kinase  
Anti-cancer synergy of dichloroacetate and EGFR tyrosine kinase inhibitors in NSCLC cell lines Journal article
Yang,Zheng, Tam,Kin Y.. Anti-cancer synergy of dichloroacetate and EGFR tyrosine kinase inhibitors in NSCLC cell lines[J]. European Journal of Pharmacology, 2016, 789, 458-467.
Authors:  Yang,Zheng;  Tam,Kin Y.
Favorite | TC[WOS]:31 TC[Scopus]:31  IF:4.2/4.3 | Submit date：2021/03/04
Dichloroacetate  Drug Combination  Epidermal Growth Factor Receptor  Erlotinib  Gefitinib  Pyruvate Dehydrogenase Kinase