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Corynoxine B targets at HMGB1/2 to enhance autophagy for α-synuclein clearance in fly and rodent models of Parkinson's disease Journal article
Qi Zhu, Juxian Song, Jia-Yue Chen, Zhenwei Yuan, Liangfeng Liu, Li-Ming Xie, Qiwen Liao, Richard D. Ye, Xiu Chen, Yepiao Yan, Jieqiong Tan, Chris Soon Heng Tan, Min Li, Jia-Hong Lu. Corynoxine B targets at HMGB1/2 to enhance autophagy for α-synuclein clearance in fly and rodent models of Parkinson's disease[J]. Acta Pharmaceutica Sinica B, 2023, 13(6), 2701-2714.
Authors:  Qi Zhu;  Juxian Song;  Jia-Yue Chen;  Zhenwei Yuan;  Liangfeng Liu; et al.
Favorite | TC[WOS]:7 TC[Scopus]:7  IF:14.7/14.1 | Submit date：2023/07/20
Autophagy  Corynoxine b  Hmgb1  Hmgb2  Neurodegenerative Disease  Parkinson's Disease  Pi3kc3  Α-synuclein  
Corynoxine B derivative CB6 prevents Parkinsonian toxicity in mice by inducing PIK3C3 complex-dependent autophagy Journal article
Zhu, Zhou, Liu, Liang feng, Su, Cheng fu, Liu, Jia, Tong, Benjamin Chun Kit, Iyaswamy, Ashok, Krishnamoorthi, Senthilkumar, Sreenivasmurthy, Sravan Gopalkrishnashetty, Guan, Xin jie, Kan, Yu xuan, Xie, Wen jian, Zhao, Chen liang, Cheung, King ho, Lu, Jia hong, Tan, Jie qiong, Zhang, Hong jie, Song, Ju xian, Li, Min. Corynoxine B derivative CB6 prevents Parkinsonian toxicity in mice by inducing PIK3C3 complex-dependent autophagy[J]. Acta Pharmacologica Sinica, 2022, 43(10), 2511-2526.
Authors:  Zhu, Zhou;  Liu, Liang feng;  Su, Cheng fu;  Liu, Jia;  Tong, Benjamin Chun Kit; et al.
Favorite | TC[WOS]:25 TC[Scopus]:21  IF:6.9/7.6 | Submit date：2022/05/17
Autophagy  Corynoxine b  Dopaminergic Neuron  
Corynoxine Protects Dopaminergic Neurons Through Inducing Autophagy and Diminishing Neuroinflammation in Rotenone-Induced Animal Models of Parkinson’s Disease Journal article
Chen, Leilei, Huang, Yujv, Yu, Xing, Lu, Jiahong, Jia, Wenting, Song, Juxian, Liu, Liangfeng, Wang, Youcui, Huang, Yingyu, Xie, Junxia, Li, Min. Corynoxine Protects Dopaminergic Neurons Through Inducing Autophagy and Diminishing Neuroinflammation in Rotenone-Induced Animal Models of Parkinson’s Disease[J]. FRONTIERS IN PHARMACOLOGY, 2021, 12, 642900.
Authors:  Chen, Leilei;  Huang, Yujv;  Yu, Xing;  Lu, Jiahong;  Jia, Wenting; et al.
Favorite | TC[WOS]:72 TC[Scopus]:76  IF:4.4/5.0 | Submit date：2021/12/07
Autophagy  Corynoxine  Neuroinflammation  Parkinson’s Disease  Rotenone  Α-synuclein  
Phosphoproteome-based kinase activity profiling reveals the critical role of MAP2K2 and PLK1 in neuronal autophagy Journal article
Chen, Lei-Lei, Wang, Yong-Bo, Song, Ju-Xian, Deng, Wan-Kun, Lu, Jia-Hong, Ma, Li-Li, Yang, Chuan-Bin, Li, Min, Xue, Yu. Phosphoproteome-based kinase activity profiling reveals the critical role of MAP2K2 and PLK1 in neuronal autophagy[J]. AUTOPHAGY, 2017, 13(11), 1969-1980.
Authors:  Chen, Lei-Lei;  Wang, Yong-Bo;  Song, Ju-Xian;  Deng, Wan-Kun;  Lu, Jia-Hong; et al.
Favorite | TC[WOS]:36 TC[Scopus]:51  IF:14.6/16.8 | Submit date：2018/10/30
Autophagy  Corynoxine  Kinase Activity  Phosphoproteome  Phosphorylation  Protein Kinase  
HMGB1 is involved in autophagy inhibition caused by SNCA/a-synuclein overexpression :A process modulated by the natural autophagy inducer corynoxine B Journal article
Song J.-X., Lu J.-H., Liu L.-F., Chen L.-L., Durairajan S.S.K., Yue Z., Zhang H.-Q., Li M.. HMGB1 is involved in autophagy inhibition caused by SNCA/a-synuclein overexpression :A process modulated by the natural autophagy inducer corynoxine B[J]. Autophagy, 2014, 10(1), 144-154.
Authors:  Song J.-X.;  Lu J.-H.;  Liu L.-F.;  Chen L.-L.;  Durairajan S.S.K.; et al.
Favorite | TC[WOS]:127 TC[Scopus]:132 | Submit date：2019/01/15
Autophagy  Corynoxine b  Hmgb1  Parkinson Disease  Snca  
Corynoxine, a natural autophagy enhancer, promotes the clearance of alpha-synuclein via Akt/mTOR pathway Journal article
Chen L.-L., Song J.-X., Lu J.-H., Yuan Z.-W., Liu L.-F., Durairajan S.S.K., Li M.. Corynoxine, a natural autophagy enhancer, promotes the clearance of alpha-synuclein via Akt/mTOR pathway[J]. Journal of Neuroimmune Pharmacology, 2014, 9(3), 380-387.
Authors:  Chen L.-L.;  Song J.-X.;  Lu J.-H.;  Yuan Z.-W.;  Liu L.-F.; et al.
Favorite | TC[WOS]:78 TC[Scopus]:84 | Submit date：2019/01/15
Alpha-synuclein  Autophagy  Corynoxine  Mtor  Parkinson's Disease