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Introducing enzymatic cleavage features and transfer learning realizes accurate peptide half-life prediction across species and organs
Journal article
Tan, Xiaorong, Liu, Qianhui, Fang, Yanpeng, Yang, Sen, Chen, Fei, Wang, Jianmin, Ouyang, Defang, Dong, Jie, Zeng, Wenbin. Introducing enzymatic cleavage features and transfer learning realizes accurate peptide half-life prediction across species and organs[J]. Briefings in Bioinformatics, 2024, 25(4), bbae350.
Authors:
Tan, Xiaorong
;
Liu, Qianhui
;
Fang, Yanpeng
;
Yang, Sen
;
Chen, Fei
; et al.
Favorite
|
TC[WOS]:
1
TC[Scopus]:
1
IF:
6.8
/
7.9
|
Submit date:2024/08/05
Drug Design
Enzymatic Cleavage Features
Half-life
Machine Learning
Peptide Drugs
Transfer Learning
Thermal degradation of (2R, 3R)-dihydromyricetin in neutral aqueous solution at 100 ℃
Journal article
Zhang, Haolin, Lin, Shiye, Xie, Ruiwei, Zhong, Weizhi, Wang, Hui, Farag, Mohamed A., Hussain, Hidayat, Arroo, Randolph R.J., Chen, Xiaojia, Xiao, Jianbo. Thermal degradation of (2R, 3R)-dihydromyricetin in neutral aqueous solution at 100 ℃[J]. Food Chemistry, 2023, 435, 137560.
Authors:
Zhang, Haolin
;
Lin, Shiye
;
Xie, Ruiwei
;
Zhong, Weizhi
;
Wang, Hui
; et al.
Favorite
|
TC[WOS]:
2
TC[Scopus]:
2
IF:
8.5
/
8.2
|
Submit date:2024/04/02
Dihydromyricetin
Dimer
Heat
Hydroxylation
Oxidation
Ring-cleavage
Post-translational Modification in Control of SIRT1 Stability during DNA Damage Response
Journal article
Ouyang, Chenxi, Lu, Guang, He, Weifeng, Bay, Boon Huat, Shen, Han Ming. Post-translational Modification in Control of SIRT1 Stability during DNA Damage Response[J]. International Journal of Biological Sciences, 2022, 18(7), 2655-2669.
Authors:
Ouyang, Chenxi
;
Lu, Guang
;
He, Weifeng
;
Bay, Boon Huat
;
Shen, Han Ming
Favorite
|
TC[WOS]:
8
TC[Scopus]:
7
IF:
8.2
/
8.3
|
Submit date:2022/07/20
Caspases
Cleavage
Ddr
Sirt1
Trim28
Ubiquitination
Structure–reactivity relationship of probes based on the H2S-mediated reductive cleavage of the C=C bond
Journal article
Wang, C., Tan, J., Zhang, X.. Structure–reactivity relationship of probes based on the H2S-mediated reductive cleavage of the C=C bond[J]. New J. Chem, 2020, 11667-11677.
Authors:
Wang, C.
;
Tan, J.
;
Zhang, X.
Favorite
|
TC[WOS]:
2
TC[Scopus]:
3
|
Submit date:2022/07/27
Structure–reactivity Relationship
H2s Probe
Reductive Cleavage
C=c Bond
Reductive cleavage of C=C bond as a new strategy for turn on dual fluorescence in effective sensing H2S
Journal article
Wang, C., Cheng, X., Tan, J., Ding, Z., Wang, W., Yuan, D., Li, G., Zhang, H., Zhang, X.. Reductive cleavage of C=C bond as a new strategy for turn on dual fluorescence in effective sensing H2S[J]. Chemical Science, 2018, 8369-8374.
Authors:
Wang, C.
;
Cheng, X.
;
Tan, J.
;
Ding, Z.
;
Wang, W.
; et al.
Favorite
|
TC[WOS]:
36
TC[Scopus]:
37
IF:
7.6
/
8.0
|
Submit date:2022/07/27
Reductive Cleavage
H2s
Turn-on Fluorescence
Sensing
Quinazolinone azolyl ethanols: Potential lead antimicrobial agents with dual action modes targeting methicillin-resistant Staphylococcus aureus DNA
Journal article
Peng X.-M., Peng L.-P., Li S., Avula S.R., Kannekanti V.K., Zhang S.-L., Tam K.Y., Zhou C.-H.. Quinazolinone azolyl ethanols: Potential lead antimicrobial agents with dual action modes targeting methicillin-resistant Staphylococcus aureus DNA[J]. Future Medicinal Chemistry, 2016, 8(16), 1927-1940.
Authors:
Peng X.-M.
;
Peng L.-P.
;
Li S.
;
Avula S.R.
;
Kannekanti V.K.
; et al.
Favorite
|
TC[WOS]:
59
TC[Scopus]:
59
|
Submit date:2018/12/18
Antibacterial
Antifungal
Dna Cleavage
Dna Intercalation
Imidazole
Quinazolinone
Triazole
'Quinazolinone azolyl ethanols: Potential lead antimicrobial agents with dual action modes targeting MRSA DNA
Journal article
Peng, X, Peng, L, Li, S, Avula, S, Kannekanti, V, Zhang, S, Tam, K. Y., Zhou, C. 'Quinazolinone azolyl ethanols: Potential lead antimicrobial agents with dual action modes targeting MRSA DNA[J]. Future Medicinal Chemistry, 2016, 1927-1940.
Authors:
Peng, X
;
Peng, L
;
Li, S
;
Avula, S
;
Kannekanti, V
; et al.
Favorite
|
TC[WOS]:
59
TC[Scopus]:
59
IF:
3.2
/
3.7
|
Submit date:2022/07/28
Antibacterial
Antifungal
Dna Cleavage
Dna Intercalation
Imidazole
Quinazolinone
Triazole
Synthesis of functionalized siloles from Si-tethered diynes
Journal article
Luo Q., Gu L., Wang C., Liu J., Zhang W., Xi Z.. Synthesis of functionalized siloles from Si-tethered diynes[J]. Tetrahedron Letters, 2009, 50(26), 3213-3215.
Authors:
Luo Q.
;
Gu L.
;
Wang C.
;
Liu J.
;
Zhang W.
; et al.
Favorite
|
TC[WOS]:
13
TC[Scopus]:
14
|
Submit date:2018/12/18
1,4-diiodo-1,3-butadiene
1,4-dilithio-1,3-butadiene
Cleavage Of Si-c Bond
Phenyl-bridged Bis-silole
Si-tethered Diynes
Silole
Zirconacyclopetadiene