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Aidi injection inhibits the migration and invasion of gefitinib-resistant lung adenocarcinoma cells by regulating the PLAT/FAK/AKT pathway Journal article
Zhang, Jingyuan, Yang, Siyun, Chen, Xiaodong, Zhang, Fanqin, Guo, Siyu, Wu, Chao, Wang, Tieshan, Wang, Haojia, Lu, Shan, Qiao, Chuanqi, Sheng, Xiaoguang, Liu, Shuqi, Zhang, Xiaomeng, Luo, Hua, Li, Qinglin, Wu, Jiarui. Aidi injection inhibits the migration and invasion of gefitinib-resistant lung adenocarcinoma cells by regulating the PLAT/FAK/AKT pathway[J]. Chinese Medicine (United Kingdom), 2025, 20(1), 2.
Authors:  Zhang, Jingyuan;  Yang, Siyun;  Chen, Xiaodong;  Zhang, Fanqin;  Guo, Siyu; et al.
Favorite | TC[WOS]:1 TC[Scopus]:0 | Submit date：2025/01/22
Non-small Cell Lung Cancer  Aidi Injection  Gefitinib Resistance  Plat/fak/akt Pathway  
Activation of the PERK/eIF2α axis is a pivotal prerequisite of taxanes to cancer cell apoptosis and renders synergism to overcome paclitaxel resistance in breast cancer cells Journal article
Cai, Wanhua, Rong, Dade, Ding, Jiayu, Zhang, Xiaomei, Wang, Yuwei, Fang, Ying, Xiao, Jing, Yang, Shulan, Wang, Haihe. Activation of the PERK/eIF2α axis is a pivotal prerequisite of taxanes to cancer cell apoptosis and renders synergism to overcome paclitaxel resistance in breast cancer cells[J]. Cancer Cell International, 2024, 24(1), 249.
Authors:  Cai, Wanhua;  Rong, Dade;  Ding, Jiayu;  Zhang, Xiaomei;  Wang, Yuwei; et al.
Favorite | TC[WOS]:1 TC[Scopus]:2  IF:5.3/5.0 | Submit date：2024/08/05
Taxane  Perk/eif2α  Tumor Drug Resistance  Breast Cancer  Er Stress  
PiRNA-4447944 promotes castration-resistant growth and metastasis of prostate cancer by inhibiting NEFH expression through forming the piRNA-4447944-PIWIL2-NEFH complex Journal article
Peng, Qiang, Chen, Yu, Xie, Tingting, Pu, Dandan, Ho, Vincy Wing Sze, Sun, Jingkai, Liu, Kang, Chan, Ronald Cheong Kin, Ding, Xiaofan, Teoh, Jeremy Yuen Chun, Wang, Xin, Chiu, Peter Ka Fung, Ng, Chi Fai. PiRNA-4447944 promotes castration-resistant growth and metastasis of prostate cancer by inhibiting NEFH expression through forming the piRNA-4447944-PIWIL2-NEFH complex[J]. International journal of biological sciences, 2024, 20(9), 3638-3655.
Authors:  Peng, Qiang;  Chen, Yu;  Xie, Tingting;  Pu, Dandan;  Ho, Vincy Wing Sze; et al.
Favorite | TC[WOS]:1 TC[Scopus]:1  IF:8.2/8.3 | Submit date：2024/08/05
Castration Resistance  Nefh  Pir-4447944  Piwi-interacting Rnas  Prostate Cancer  
Self-Assembled Micelles Based on Ginsenoside Rg5 for the Targeted Treatment of PTX-Resistant Tumors Journal article
Gao, Feiyan, Ma, Zhongyi, Luo, Xing, Wang, Yahua, Liu, Xinlong, Tang, Mei, Chen, Junyu, Tu, Liangxing, Ouyang, Defang, Zheng, Ji, Li, Chong. Self-Assembled Micelles Based on Ginsenoside Rg5 for the Targeted Treatment of PTX-Resistant Tumors[J]. Molecular Pharmaceutics, 2024, 21(7), 3502-3512.
Authors:  Gao, Feiyan;  Ma, Zhongyi;  Luo, Xing;  Wang, Yahua;  Liu, Xinlong; et al.
Favorite | TC[WOS]:1 TC[Scopus]:2  IF:4.5/4.6 | Submit date：2024/07/04
Chemotherapy Resistance  Paclitaxel  Paclitaxel-ginsenoside Micelles  Prostate Cancer Treatment  Severe Neurotoxicity  
Nanoenabled intracellular zinc bursting for efficacious reversal of gefitinib resistance in lung cancer Journal article
Li, Junnan, Assaraf, Yehuda G., Zuo, Weimin, Lin, Ziqi, Leong, Ka Weng, Zhao, Qi, Zhu, Lipeng, Kwok, Hang Fai. Nanoenabled intracellular zinc bursting for efficacious reversal of gefitinib resistance in lung cancer[J]. International Journal of Biological Sciences, 2024, 20(8), 3028-3045.
Authors:  Li, Junnan;  Assaraf, Yehuda G.;  Zuo, Weimin;  Lin, Ziqi;  Leong, Ka Weng; et al.
Favorite | TC[WOS]:2 TC[Scopus]:3  IF:8.2/8.3 | Submit date：2024/07/04
Cancer Therapy  Drug Resistance  Lung Cancer  Reactive Oxygen Species (Ros)  Zeolitic Imidazolate Framework-8 (Zif-8)  Zn2++++  
MYC Oncogene: A Druggable Target for Treating Cancers with Natural Products Journal article
Chan, Ka Iong, Zhang, Siyuan, Li, Guodong, Xu, Yida, Cui, Liao, Wang, Yitao, Su, Huanxing, Tan, Wen, Zhong, Zhangfeng. MYC Oncogene: A Druggable Target for Treating Cancers with Natural Products[J]. Aging and Disease, 2024, 15(2), 640-697.
Authors:  Chan, Ka Iong;  Zhang, Siyuan;  Li, Guodong;  Xu, Yida;  Cui, Liao; et al.
Favorite | TC[WOS]:17 TC[Scopus]:14  IF:7.0/7.1 | Submit date：2023/08/31
Myc  Cancer  Immune Response  Multidrug Resistance  Natural Product  Herbal Medicine  
Paris saponin VII reverses resistance to PARP inhibitors by regulating ovarian cancer tumor angiogenesis and glycolysis through the RORα/ECM1/VEGFR2 signaling axis. Journal article
Wang MengFei, Yuan ChenYue, Wu Zong, Xu Meng, Chen ZiQi, Yao JiaLiang, Que ZuJun, Tian JianHui, Leung Elaine Lai Han, Wang ZiLiang. Paris saponin VII reverses resistance to PARP inhibitors by regulating ovarian cancer tumor angiogenesis and glycolysis through the RORα/ECM1/VEGFR2 signaling axis.[J]. International Journal of Biological Sciences, 2024, 20(7), 2454-2475.
Authors:  Wang MengFei;  Yuan ChenYue;  Wu Zong;  Xu Meng;  Chen ZiQi; et al.
Adobe PDF | Favorite | TC[WOS]:1 TC[Scopus]:1  IF:8.2/8.3 | Submit date：2024/06/10
Angiogenesis  Ecm1  Glycolysis  Ovarian Cancer  Paris Saponin Vii  Parpi Resistance  Rorα  Vegfr2  
Editorial: New progress in cancer biomarkers and therapy Other
2024-03-01
Authors:  Guohui Sun;  HE CHENGWEI;  Jianhua Wang
Adobe PDF | Favorite | TC[WOS]:0 TC[Scopus]:0 | Submit date：2024/08/14
Bioinformatics  Biomarkers  Cancer  Tumor Microenvironment  Tumor Prognosis  Tumor Resistance  Tumor Therapy  
Fighting drug-resistant lung cancer by induction of NAD(P)H:quinone oxidoreductase 1 (NQO1)-mediated ferroptosis Journal article
Yu,Jie, Zhong,Bingling, Zhao,Lin, Hou,Ying, Ai,Nana, Lu,Jin Jian, Ge,Wei, Chen,Xiuping. Fighting drug-resistant lung cancer by induction of NAD(P)H:quinone oxidoreductase 1 (NQO1)-mediated ferroptosis[J]. Drug Resistance Updates, 2023, 70, 100977.
Authors:  Yu,Jie;  Zhong,Bingling;  Zhao,Lin;  Hou,Ying;  Ai,Nana; et al.
Favorite | TC[WOS]:38 TC[Scopus]:37  IF:15.8/18.1 | Submit date：2023/08/03
Drug-resistance  Ferroptosis  Lung Cancer  Mam  Nqo1  
Reprogramming of TAMs via the STAT3/CD47-SIRPα axis promotes acquired resistance to EGFR-TKIs in lung cancer Journal article
Lu, Jiaye, Li, Jingwei, Lin, Ziyou, Li, Huaxuan, Lou, Linlin, Ding, Wen, Ouyang, Shumin, Wu, Yonghui, Wen, Yuanzhen, Chen, Xiaobing, Yue, Peibin, Wang, Yuanxiang, Liu, Peiqing, Lu, Jinjian, Zhang, Jian, Feng, Weineng, Zhang, Xiaolei. Reprogramming of TAMs via the STAT3/CD47-SIRPα axis promotes acquired resistance to EGFR-TKIs in lung cancer[J]. Cancer Letters, 2023, 564, 216205.
Authors:  Lu, Jiaye;  Li, Jingwei;  Lin, Ziyou;  Li, Huaxuan;  Lou, Linlin; et al.
Favorite | TC[WOS]:31 TC[Scopus]:31  IF:9.1/8.3 | Submit date：2023/07/20
Acquired Tki Resistance  Cd47  Lung Cancer  Stat3  Tams