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Synthesis and biological evaluation of (R)-3,3,3-trifluoro-2-hydroxy-2- methylpropionamides as pyruvate dehydrogenase kinase 1 (PDK1) inhibitors to reduce the growth of cancer cells Journal article
Zhang, S.L., Zhang, W., Yang, Z., Hu, X., Tam, K. Y.. Synthesis and biological evaluation of (R)-3,3,3-trifluoro-2-hydroxy-2- methylpropionamides as pyruvate dehydrogenase kinase 1 (PDK1) inhibitors to reduce the growth of cancer cells[J]. European Journal of Pharmaceutical Sciences, 2017, 87-92.
Authors:  Zhang, S.L.;  Zhang, W.;  Yang, Z.;  Hu, X.;  Tam, K. Y.
Favorite | TC[WOS]:7 TC[Scopus]:7  IF:4.3/4.2 | Submit date：2022/07/28
Pyruvate Dehydrogenase Kinase  Pyruvate Dehydrogenase Complex  Anti-proliferation  Binding Affinity