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Impairment of the autophagy–lysosomal pathway in Alzheimer's diseases: Pathogenic mechanisms and therapeutic potential Journal article
Wei Zhang, Chengchao Xu, Jichao Sun, Han-Ming Shen, Jigang Wang, Chuanbin Yang. Impairment of the autophagy–lysosomal pathway in Alzheimer's diseases: Pathogenic mechanisms and therapeutic potential[J]. Acta Pharmaceutica Sinica B, 2022, 12(3), 1019-1040.
Authors:  Wei Zhang;  Chengchao Xu;  Jichao Sun;  Han-Ming Shen;  Jigang Wang; et al.
Favorite | TC[WOS]:82 TC[Scopus]:84  IF:14.7/14.1 | Submit date：2022/04/06
Alzheimer’s Disease (Ad)  Amyloid Beta (Ab) Peptides  Mapt/tau  Autophagy–lysosomal Pathway  Autophagy Enhancers  Autophagy  Mitophagy  Neurodegenerative Diseases  
Lysosomal TPCN (two pore segment channel) inhibition ameliorates beta-amyloid pathology and mitigates memory impairment in Alzheimer disease Journal article
Tong, Benjamin Chun Kit, Wu, Aston Jiaxi, Huang, Alexis Shiying, Dong, Rui, Malampati, Sandeep, Iyaswamy, Ashok, Krishnamoorthi, Senthilkumar, Sreenivasmurthy, Sravan Gopalkrishnashetty, Zhu, Zhou, Su, Chengfu, Liu, Jia, Song, Juxian, Lu, Jia Hong, Tan, Jieqiong, Pan, Weidong, Li, Min, Cheung, King Ho. Lysosomal TPCN (two pore segment channel) inhibition ameliorates beta-amyloid pathology and mitigates memory impairment in Alzheimer disease[J]. Autophagy, 2021, 18(3), 624-642.
Authors:  Tong, Benjamin Chun Kit;  Wu, Aston Jiaxi;  Huang, Alexis Shiying;  Dong, Rui;  Malampati, Sandeep; et al.
Favorite | TC[WOS]:30 TC[Scopus]:30  IF:14.6/16.8 | Submit date：2022/05/17
Alzheimer Disease  Autophagy-lysosomal Pathway  Calcium Ion  Presenilin-1  Two Pore Segment Channel 2