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Aidi injection inhibits the migration and invasion of gefitinib-resistant lung adenocarcinoma cells by regulating the PLAT/FAK/AKT pathway Journal article
Zhang, Jingyuan, Yang, Siyun, Chen, Xiaodong, Zhang, Fanqin, Guo, Siyu, Wu, Chao, Wang, Tieshan, Wang, Haojia, Lu, Shan, Qiao, Chuanqi, Sheng, Xiaoguang, Liu, Shuqi, Zhang, Xiaomeng, Luo, Hua, Li, Qinglin, Wu, Jiarui. Aidi injection inhibits the migration and invasion of gefitinib-resistant lung adenocarcinoma cells by regulating the PLAT/FAK/AKT pathway[J]. Chinese Medicine (United Kingdom), 2025, 20(1), 2.
Authors:  Zhang, Jingyuan;  Yang, Siyun;  Chen, Xiaodong;  Zhang, Fanqin;  Guo, Siyu; et al.
Favorite | TC[WOS]:1 TC[Scopus]:0 | Submit date：2025/01/22
Non-small Cell Lung Cancer  Aidi Injection  Gefitinib Resistance  Plat/fak/akt Pathway  
Artemisinin Suppressed Melanoma Recurrence and Metastasis after Radical Surgery through the KIT/PI3K/AKT Pathway Journal article
Zhou, Zhiwei, Farhan, Mohd, Xing, Xingan, Zhou, Wenshu, Lin, Ruohong, Zeng, Shan, Li, Mengfang, Zheng, Wenhua. Artemisinin Suppressed Melanoma Recurrence and Metastasis after Radical Surgery through the KIT/PI3K/AKT Pathway[J]. International Journal of Biological Sciences, 2025, 21(1), 75-94.
Authors:  Zhou, Zhiwei;  Farhan, Mohd;  Xing, Xingan;  Zhou, Wenshu;  Lin, Ruohong; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:8.2/8.3 | Submit date：2025/01/22
Artemisinin  Melanoma  Post-surgery Model  C-kit  Akt  
Tetramethylpyrazine Analogue T-006 Protects Neuronal and Endothelial Cells Against Oxidative Stress via PI3K/AKT/mTOR and Nrf2 Signaling Journal article
Zhang, Guiliang, Liang, Zirong, Wang, Yuqiang, Zhang, Zaijun, Hoi, Pui Man. Tetramethylpyrazine Analogue T-006 Protects Neuronal and Endothelial Cells Against Oxidative Stress via PI3K/AKT/mTOR and Nrf2 Signaling[J]. Antioxidants, 2024, 13(10), 1272.
Authors:  Zhang, Guiliang;  Liang, Zirong;  Wang, Yuqiang;  Zhang, Zaijun;  Hoi, Pui Man
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:6.0/6.7 | Submit date：2024/12/05
Tetramethylpyrazine Analogue T-006  Oxidative Cytotoxicity  Excessive Glutamate  Ogd/r  Pi3k/akt  Nrf2/ho-1  Mtor  
Rasagiline Exerts Neuroprotection towards Oxygen–Glucose-Deprivation/Reoxygenation-Induced GAPDH-Mediated Cell Death by Activating Akt/Nrf2 Signaling Journal article
Lecht, Shimon, Lahiani, Adi, Klazas, Michal, Naamneh, Majdi Saleem, Rubin, Limor, Dong, Jiayi, Zheng, Wenhua, Lazarovici, Philip. Rasagiline Exerts Neuroprotection towards Oxygen–Glucose-Deprivation/Reoxygenation-Induced GAPDH-Mediated Cell Death by Activating Akt/Nrf2 Signaling[J]. Biomedicines, 2024, 12(7), 1592.
Authors:  Lecht, Shimon;  Lahiani, Adi;  Klazas, Michal;  Naamneh, Majdi Saleem;  Rubin, Limor; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:3.9/4.1 | Submit date：2024/08/05
Akt  Cell Death  Gapdh  Ischemia-like Insult  Neuroprotection  Nrf2  Phosphorylation  Rasagiline  Ros  Pc 12 Neuronal Model  Α-synuclein  Parkinson’s Disease  Stroke  
Exploiting new strategies in combating head and neck carcinoma: A comprehensive review on phytochemical approaches passing through PI3K/Akt/mTOR signaling pathway Journal article
Iranpanah, Amin, Majnooni, Mohammad Bagher, Biganeh, Hossein, Amirian, Roshanak, Rastegari-Pouyani, Mohsen, Filosa, Rosanna, Cheang, Wai San, Fakhri, Sajad, Khan, Haroon. Exploiting new strategies in combating head and neck carcinoma: A comprehensive review on phytochemical approaches passing through PI3K/Akt/mTOR signaling pathway[J]. Phytotherapy Research, 2024, 38(7), 3736-3762.
Authors:  Iranpanah, Amin;  Majnooni, Mohammad Bagher;  Biganeh, Hossein;  Amirian, Roshanak;  Rastegari-Pouyani, Mohsen; et al.
Favorite | TC[WOS]:0 TC[Scopus]:1  IF:6.1/7.0 | Submit date：2024/09/03
Cancer  Head And Neck  Phytochemical  Pi3k/akt/mtor Pathway  
Artemisinins suppress melanoma recurrence and metastasis after radical surgery by inhibiting the c-KIT/PI3K/AKT signaling pathway Conference paper
Zhiwei Zhou, ZHENG WENHUA. Artemisinins suppress melanoma recurrence and metastasis after radical surgery by inhibiting the c-KIT/PI3K/AKT signaling pathway[C], 2024.
Authors:  Zhiwei Zhou;  ZHENG WENHUA
Favorite |  | Submit date：2024/08/31
Artemisinin  Melanoma  Post-surgery Model  C-kit  Akt  
Artemisinin diminished the hyperphosphorylation of Tau induced by Aβ1-42 via the AKT/GSK-3β pathway in vitro and in vivo Alzheimer's disease modle Conference paper
Yitian Chen, Wenhua Zheng. Artemisinin diminished the hyperphosphorylation of Tau induced by Aβ1-42 via the AKT/GSK-3β pathway in vitro and in vivo Alzheimer's disease modle[C], 2024.
Authors:  Yitian Chen;  Wenhua Zheng
Favorite |  | Submit date：2024/08/31
Alzheimer’s Disease, Aβ, Tau Hyperphosphorylation, Artemisinin, Gsk-3β, P13k/akt  
Cayratia albifolia C.L.Li exerts anti-rheumatoid arthritis effect by inhibiting macrophage activation and neutrophil extracellular traps (NETs) Journal article
Wang, Wei, Zhang, Zai Qi, Zhang, Yi Chi, Wu, Yi Qiang, Yang, Zhuo, Zheng, Yong Zhe, Lu, Jia Hong, Tu, Peng Fei, Zeng, Ke Wu. Cayratia albifolia C.L.Li exerts anti-rheumatoid arthritis effect by inhibiting macrophage activation and neutrophil extracellular traps (NETs)[J]. Chinese Medicine (United Kingdom), 2024, 19(1), 42.
Authors:  Wang, Wei;  Zhang, Zai Qi;  Zhang, Yi Chi;  Wu, Yi Qiang;  Yang, Zhuo; et al.
Favorite | TC[WOS]:2 TC[Scopus]:3  IF:5.3/5.5 | Submit date：2024/05/16
Cayratia Albifolia C.l.li  Macrophage  Netosis  Pi3k-akt Pathway  Rheumatoid Arthritis  
BET inhibition induces synthetic lethality in PTEN deficient colorectal cancers via dual action on p21CIP1/WAF1 Journal article
Ren, Guowen, Chen, Jinghong, Pu, Yue, Yang, Eun Ju, Tao, Shishi, Mou, Pui Kei, Chen, Li Jie, Zhu, Wenli, Chan, Kin Long, Luo, Guanghui, Deng, Chuxia, Shim, Joong Sup. BET inhibition induces synthetic lethality in PTEN deficient colorectal cancers via dual action on p21CIP1/WAF1[J]. International Journal of Biological Sciences, 2024, 20(6), 1978-1991.
Authors:  Ren, Guowen;  Chen, Jinghong;  Pu, Yue;  Yang, Eun Ju;  Tao, Shishi; et al.
Favorite | TC[WOS]:1 TC[Scopus]:1  IF:8.2/8.3 | Submit date：2024/05/16
Akt  Bet  Colorectal Cancer  Myc  P21  PhosphorylAted P21 At Thr145  Pten  Synthetic Lethality  
Electric field stimulation boosts neuronal differentiation of neural stem cells for spinal cord injury treatment via PI3K/Akt/GSK-3β/β-catenin activation Journal article
Liu, Qian, Telezhkin, Vsevolod, Jiang, Wenkai, Gu, Yu, Wang, Yan, Hong, Wei, Tian, Weiming, Yarova, Polina, Zhang, Gaofeng, Lee, Simon Ming yuen, Zhang, Peng, Zhao, Min, Allen, Nicholas D., Hirsch, Emilio, Penninger, Josef, Song, Bing. Electric field stimulation boosts neuronal differentiation of neural stem cells for spinal cord injury treatment via PI3K/Akt/GSK-3β/β-catenin activation[J]. Cell and Bioscience, 2023, 13(1).
Authors:  Liu, Qian;  Telezhkin, Vsevolod;  Jiang, Wenkai;  Gu, Yu;  Wang, Yan; et al.
Favorite | TC[WOS]:23 TC[Scopus]:27  IF:6.1/7.0 | Submit date：2023/02/28
Neural Stem Cells  Electric Field Stimulation  Neuronal Differentiation  Pi3k/akt/gsk-3β/β-catenin  Spinal Cord Injury