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SSRI antidepressant citalopram reverses the Warburg effect to inhibit hepatocellular carcinoma by directly targeting GLUT1 Journal article
Dong, Fangyuan, He, Kang, Zhang, Shan, Song, Kaiyuan, Jiang, Luju, Hu, Li Peng, Li, Qing, Zhang, Xue Li, Zhang, Naiqi, Li, Bo Tai, Zhu, Li Li, Li, Jun, Feng, Mingxuan, Gao, Yunchen, Chen, Jie, Hu, Xiaona, Wang, Jiaofeng, Jiang, Chongyi, Wang, Cun, Zhu, Helen He, Da, Lin Tai, Ji, Jianguang, Zhang, Zhi Gang, Bao, Zhijun, Jiang, Shu Heng. SSRI antidepressant citalopram reverses the Warburg effect to inhibit hepatocellular carcinoma by directly targeting GLUT1[J]. Cell Reports, 2024, 43(10), 114818.
Authors:  Dong, Fangyuan;  He, Kang;  Zhang, Shan;  Song, Kaiyuan;  Jiang, Luju; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:7.5/8.5 | Submit date：2024/11/05
Aerobic Glycolysis  Drug Discovery  Drug Repurposing  Sert  Slc6a4  
Dichloroacetophenone derivatives as pyruvate dehydrogenase kinase inhibitor in non-small cell lung cancer models Presentation
会议地点: University Rectorate, Belgrade, Serbia, 会议日期: 4-6 September, 2023, 报告日期: 2023-09-05
Authors:  TAM KIN YIP
Favorite |  | Submit date：2024/08/30
Cancer Metabolism  Aerobic Glycolysis  Pyruvate Dehydrogenase Kinase  
LC/MS/MS method revealed that lung cancer cells exhibited distinct metabolite profiles upon the treatment with different anticancer pyruvate dehydrogenase kinases (PDKs) inhibitors Presentation
会议地点: Hotel Park, Split, Croatia, 会议日期: 9-11 September 2019, 报告日期: 2019-09-09
Authors:  TAM KIN YIP
Favorite |  | Submit date：2024/08/30
Aerobic Glycolysis  Lc-ms/ms  Pyruvate Dehydrogenase Kinases  Cancer Metabolism  
Liquid Chromatography-Tandem Mass Spectrometry Method Revealed that Lung Cancer Cells Exhibited Distinct Metabolite Profiles upon the Treatment with Different Pyruvate Dehydrogenase Kinase Inhibitors Journal article
Zhang, Wen, Hu, Xiaohui, Zhou, Wei, Tam, Kin Yip. Liquid Chromatography-Tandem Mass Spectrometry Method Revealed that Lung Cancer Cells Exhibited Distinct Metabolite Profiles upon the Treatment with Different Pyruvate Dehydrogenase Kinase Inhibitors[J]. JOURNAL OF PROTEOME RESEARCH, 2018, 17(9), 3012-3021.
Authors:  Zhang, Wen;  Hu, Xiaohui;  Zhou, Wei;  Tam, Kin Yip
Favorite | TC[WOS]:18 TC[Scopus]:18  IF:3.8/4.1 | Submit date：2018/10/30
Aerobic Glycolysis  Azd7545  Dichloroacetate  Lc-ms/ms  Pyruvate Dehydrogenase Kinases  Cancer Metabolism  
Liquid Chromatography–Tandem Mass Spectrometry Method Revealed that Lung Cancer Cells Exhibited Distinct Metabolite Profiles upon the Treatment with Different Pyruvate Dehydrogenase Kinase Inhibitors Journal article
Zhang, W., Hu, X., Zhou, W., Tam, K. Y.. Liquid Chromatography–Tandem Mass Spectrometry Method Revealed that Lung Cancer Cells Exhibited Distinct Metabolite Profiles upon the Treatment with Different Pyruvate Dehydrogenase Kinase Inhibitors[J]. Journal of Proteome Research, 2018, 1-10.
Authors:  Zhang, W.;  Hu, X.;  Zhou, W.;  Tam, K. Y.
Favorite | TC[WOS]:18 TC[Scopus]:18  IF:3.8/4.1 | Submit date：2022/07/28
Aerobic Glycolysis  Azd7545  Cancer Metabolism  Dichloroacetate  Lc−ms/ms  Pyruvate Dehydrogenase Kinases  
NFκB up-regulation of glucose transporter 3 is essential for hyperactive mammalian target of rapamycin-induced aerobic glycolysis and tumor growth Journal article
Zha X., Hu Z., Ji S., Jin F., Jiang K., Li C., Zhao P., Tu Z., Chen X., Di L., Zhou H., Zhang H.. NFκB up-regulation of glucose transporter 3 is essential for hyperactive mammalian target of rapamycin-induced aerobic glycolysis and tumor growth[J]. Cancer Letters, 2015, 359(1), 97-106.
Authors:  Zha X.;  Hu Z.;  Ji S.;  Jin F.;  Jiang K.; et al.
Favorite | TC[WOS]:49 TC[Scopus]:50 | Submit date：2018/12/21
Aerobic Glycolysis  Glut3  Mtor  Nfκb  Tumorigenesis  
Targeting tumor metabolism for cancer treatment: Is pyruvate dehydrogenase kinases (PDKs) a viable anticancer target? Journal article
Wen Zhang, Shao-Lin Zhang, Xiaohui Hu, Kin Yip Tam. Targeting tumor metabolism for cancer treatment: Is pyruvate dehydrogenase kinases (PDKs) a viable anticancer target?[J]. International Journal of Biological Sciences, 2015, 11(12), 1390-1400.
Authors:  Wen Zhang;  Shao-Lin Zhang;  Xiaohui Hu;  Kin Yip Tam
Favorite | TC[WOS]:118 TC[Scopus]:125  IF:8.2/8.3 | Submit date：2019/01/07
Aerobic Glycolysis  Pyruvate Dehydrogenase Kinases  Tumor Metabolism  Pyruvate Dehydrogenase Complex