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Schisantherin A protects against 6-OHDA-induced dopaminergic neuron damage in zebrafish and cytotoxicity in SH-SY5Y cells through the ROS/NO and AKT/GSK3β pathways Journal article
Lun Qing Zhang, Fei Sa, Cheong Meng Chong, Ying Wang, Zhong Yan Zhou, Raymond Chuen Chung Chang, Shun Wan Chan, Pui Man Hoi, Simon Ming Yuen Lee. Schisantherin A protects against 6-OHDA-induced dopaminergic neuron damage in zebrafish and cytotoxicity in SH-SY5Y cells through the ROS/NO and AKT/GSK3β pathways[J]. Journal of Ethnopharmacology, 2015, 8-15.
Authors:  Lun Qing Zhang;  Fei Sa;  Cheong Meng Chong;  Ying Wang;  Zhong Yan Zhou; et al.
Favorite | TC[WOS]:51 TC[Scopus]:60 | Submit date：2022/07/27
6-hydroxydopamine (6-ohda)  Oxidative Stress  Parkinson׳s Disease  Schisantherin a  
Schisantherin A protects against 6-OHDA-induced dopaminergic neuron damage in zebrafish and cytotoxicity in SH-SY5Y cells through the ROS/NO and AKT/GSK3 β pathways Journal article
Lun Qing Zhang, Fei Sa, Cheong Meng Chong, Ying Wang, Zhong Yan Zhou, Raymond Chuen Chung Chang, Shun Wan Chan, Pui Man Hoi, Simon Ming Yuen Lee. Schisantherin A protects against 6-OHDA-induced dopaminergic neuron damage in zebrafish and cytotoxicity in SH-SY5Y cells through the ROS/NO and AKT/GSK3 β pathways[J]. JOURNAL OF ETHNOPHARMACOLOGY, 2015, 170, 8-15.
Authors:  Lun Qing Zhang;  Fei Sa;  Cheong Meng Chong;  Ying Wang;  Zhong Yan Zhou; et al.
Favorite | TC[WOS]:51 TC[Scopus]:60  IF:4.8/4.8 | Submit date：2020/04/15
6-hydroxydopamine (6-ohda)  Oxidative Stress  Parkinson׳s Disease  Schisantherin a  
A novel tetramethylpyrazine bis-nitrone (TN-2) protects against 6-hydroxyldopamine-induced neurotoxicity via modulation of the NF-kappa B and the PKC alpha/PI3-K/Akt pathways Journal article
Xu, Da-Ping, Zhang, Kun, Zhang, Zai-Jun, Sun, Ye-Wei, Guo, Bao-Jian, Wang, Yu-Qiang, Hoi, Pui-Man, Han, Yi-Fan, Lee, Simon Ming-Yuen. A novel tetramethylpyrazine bis-nitrone (TN-2) protects against 6-hydroxyldopamine-induced neurotoxicity via modulation of the NF-kappa B and the PKC alpha/PI3-K/Akt pathways[J]. NEUROCHEMISTRY INTERNATIONAL, 2014, 78, 76-85.
Authors:  Xu, Da-Ping;  Zhang, Kun;  Zhang, Zai-Jun;  Sun, Ye-Wei;  Guo, Bao-Jian; et al.
Favorite | TC[WOS]:25 TC[Scopus]:25  IF:4.4/3.8 | Submit date：2020/04/15
Neuroinflammation  Tetramethylpyrazine Derivative  6-hydroxydopamine  Neuroprotection  
Therapeutic effects of multifunctional tetramethylpyrazine nitrone on models of Parkinson's disease in vitro and in vivo Journal article
Baojian Guo, Daping Xu, Hongwei Duan, Jing Du, Zaijun Zhang, Simon MingYuen Lee, Yuqiang Wang. Therapeutic effects of multifunctional tetramethylpyrazine nitrone on models of Parkinson's disease in vitro and in vivo[J]. Biological and Pharmaceutical Bulletin, 2014, 37(2), 274-285.
Authors:  ; et al.
Favorite | TC[WOS]:37 TC[Scopus]:43 | Submit date：2018/11/06
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (Mptp)  6-hydroxydopamine (6-ohda)  Oxidative Stress  Parkinson's Disease  Tetramethylpyrazine Nitrone  
Neuroprotective effects of Astragaloside IV in 6-hydroxydopamine-treated primary nigral cell culture Journal article
Chan W.-S., Durairajan S.S.K., Lu J.-H., Wang Y., Xie L.-X., Kum W.-F., Koo I., Yung K.K.L., Li M.. Neuroprotective effects of Astragaloside IV in 6-hydroxydopamine-treated primary nigral cell culture[J]. Neurochemistry International, 2009, 55(6), 414-422.
Authors:  Chan W.-S.;  Durairajan S.S.K.;  Lu J.-H.;  Wang Y.;  Xie L.-X.; et al.
Favorite | TC[WOS]:86 TC[Scopus]:104 | Submit date：2019/01/15
6-hydroxydopamine  Astragaloside Iv  Nigral Primary Cell Cultures  Nitric Oxide Synthase  Parkinson's Disease  Tyrosine Hydroxylase