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Cytosolic calcium mediates RIP1/RIP3 complex-dependent necroptosis through JNK activation and mitochondrial ROS production in human colon cancer cells. Journal article
Sun, W, Wu, XX, Gao, HW, Yu, J, Zhao, WW, Lu, J., Wang, JH, Du, GH, Chen, X. P.. Cytosolic calcium mediates RIP1/RIP3 complex-dependent necroptosis through JNK activation and mitochondrial ROS production in human colon cancer cells.[J]. Free Radical Biology & Medicine, 2017, 433-444.
Authors:  Sun, W;  Wu, XX;  Gao, HW;  Yu, J;  Zhao, WW; et al.
Favorite |   IF:7.1/7.9 | Submit date：2022/03/31
Necroptosis  C-jun N-terminal Kinase  Calcium  
Hypaconitine inhibits TGF-β1-induced epithelial-mesenchymal transition and suppresses adhesion, migration, and invasion of lung cancer A549 cells. Journal article
Feng, HT, Zhao, WW, Lu, J., Wang, Y. T., Chen, X. P.. Hypaconitine inhibits TGF-β1-induced epithelial-mesenchymal transition and suppresses adhesion, migration, and invasion of lung cancer A549 cells.[J]. Chinese Journal of Natural Medicines, 2017, 427-435.
Authors:  Feng, HT;  Zhao, WW;  Lu, J.;  Wang, Y. T.;  Chen, X. P.
Favorite |  | Submit date：2022/03/31
Emt  Hypaconitine  Tgf-β1  Nf-κb  
Chemical Constituents and Biological Research on Plants in the Genus Curcuma. Journal article
Sun, W, Wang, S, Zhao, WW, Wu, CH, Guo, SH, Gao, HW, Tao, HX, Lu, J., Wang, Y. T., Chen, X. P.. Chemical Constituents and Biological Research on Plants in the Genus Curcuma.[J]. Critical Reviews in Food Science and Nutrition, 2017, 1451-1523.
Authors:  Sun, W;  Wang, S;  Zhao, WW;  Wu, CH;  Guo, SH; et al.
Favorite |   IF:7.3/10.3 | Submit date：2022/03/31
Chemical Constituents  Bioactivity  The Genus Curcuma  
Cryptotanshinone Induces Pro-death Autophagy through JNK Signaling Mediated by Reactive Oxygen Species Generation in Lung Cancer Cells. Journal article
Hao, WH, Zhang, XN, Zhao, WW, Zhu, H, Liu, ZY, Lu, J., Chen, X. P.. Cryptotanshinone Induces Pro-death Autophagy through JNK Signaling Mediated by Reactive Oxygen Species Generation in Lung Cancer Cells.[J]. Anti-Cancer Agents in Medicinal Chemistry, 2016, 593-600.
Authors:  Hao, WH;  Zhang, XN;  Zhao, WW;  Zhu, H;  Liu, ZY; et al.
Favorite |   IF:2.6/2.5 | Submit date：2022/03/31
Cryptotanshinone  Autophagy  Jnk  Ros  
2-Methoxy-6-acetyl-7-methyljuglone (MAM), a natural naphthoquinone, induces NO-dependent apoptosis and necroptosis by H2O2-dependent JNK activation in cancer cells. Journal article
Sun, W, Bao, JL, Lin, W, Gao, HW, Zhao, WW, Zhang, Q. W., Leung, C. H., Ma, DL, Lu, J., Chen, X. P.. 2-Methoxy-6-acetyl-7-methyljuglone (MAM), a natural naphthoquinone, induces NO-dependent apoptosis and necroptosis by H2O2-dependent JNK activation in cancer cells.[J]. Free Radical Biology & Medicine, 2016, 61-77.
Authors:  Sun, W;  Bao, JL;  Lin, W;  Gao, HW;  Zhao, WW; et al.
Favorite |   IF:7.1/7.9 | Submit date：2022/03/31
Apoptosis  Cancer  Mam  No  Necroptosis  Ros  
Cucurbitacin B induces DNA damage, G2/M phase arrest, and apoptosis mediated by reactive oxygen species (ROS) in K562 cells Journal article
Guo, JJ, Zhao, WW, Hao, WH, Ren, GW, Lu, J., Chen, XP. Cucurbitacin B induces DNA damage, G2/M phase arrest, and apoptosis mediated by reactive oxygen species (ROS) in K562 cells[J]. Anti-Cancer Agents in Medicinal Chemistry, 2014, 1146-1153.
Authors:  Guo, JJ;  Zhao, WW;  Hao, WH;  Ren, GW;  Lu, J.; et al.
Favorite |  | Submit date：2022/03/31
Cucurbitacin  Ros  Cell Death  Dna Damage  Cancer