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Small molecule deoxynyboquinone triggers alkylation and ubiquitination of Keap1 at Cys489 on Kelch domain for Nrf2 activation and inflammatory therapy Journal article
Linghu, Ke-Gang, Zhang, Tian, Zhang, Guang-Tao, Lv, Peng, Zhang, Wenjun, Zhao, Guanding, Xiong, Shihong, Zhao, Mingming, Chen, Meiwan, HU YUANJIA, Zhang, Changsheng, Yu, Hua. Small molecule deoxynyboquinone triggers alkylation and ubiquitination of Keap1 at Cys489 on Kelch domain for Nrf2 activation and inflammatory therapy[J]. Journal of Pharmaceutical Analysis, 2024, 14(3), 401-415.
Authors:  Linghu, Ke-Gang;  Zhang, Tian;  Zhang, Guang-Tao;  Lv, Peng;  Zhang, Wenjun; et al.
Favorite | TC[WOS]:7 TC[Scopus]:9  IF:6.1/6.8 | Submit date：2024/01/02
Deoxynyboquinone  Anti-inflammation  Target  Keap1/nrf2  Alkylation  Ubiquitination  
Anti-inflammatory/anti-oxidant properties and the UPLC-QTOF/MS-based metabolomics discrimination of three yellow camellia species Journal article
Zhao, Mingming, Linghu, Ke-Gang, Xiao, Linxuan, Hua, Tianyi, Zhao, Guanding, Chen, Qiling, Xiong, Shihang, Shen, Liyu, Yu, Jinyu, Hou, Xiaotao, Hao, Erwei, Du, Zhengcai, Deng, Jiagang, Bai, Gang, Chen, Xiaojia, Li, Ling, Li, Peng, Yu, Hua. Anti-inflammatory/anti-oxidant properties and the UPLC-QTOF/MS-based metabolomics discrimination of three yellow camellia species[J]. Food Research International, 2022, 160, 111628.
Authors:  Zhao, Mingming;  Linghu, Ke-Gang;  Xiao, Linxuan;  Hua, Tianyi;  Zhao, Guanding; et al.
Favorite | TC[WOS]:14 TC[Scopus]:14  IF:7.0/7.4 | Submit date：2022/08/18
Yellow Camellias  Discrimination  Metabolomics  Fingerprint  Anti -inflammation  Anti -oxidant  
Comprehensive comparison on the anti-inflammation and GC-MS-based metabolomics discrimination between Bupleuri chinense DC. and B. scorzonerifolium Willd Journal article
Zhao, Mingming, Xiao, Linxuan, Linghu, Ke Gang, Zhao, Guanding, Chen, Qiling, Shen, Liyu, Dar, Parsa, Chen, Meiwan, Hu, Yuan, Zhang, Jinming, Yu, Hua. Comprehensive comparison on the anti-inflammation and GC-MS-based metabolomics discrimination between Bupleuri chinense DC. and B. scorzonerifolium Willd[J]. Frontiers in Pharmacology, 2022, 13, 1005011.
Authors:  Zhao, Mingming;  Xiao, Linxuan;  Linghu, Ke Gang;  Zhao, Guanding;  Chen, Qiling; et al.
Favorite | TC[WOS]:6 TC[Scopus]:7  IF:4.4/5.0 | Submit date：2023/01/30
Anti-infammation  Bupleuri Radix  Gc-ms  Metabolomics  Species Discrimination  
Structural characterization and discrimination of three yellow camellia species with UPLC-QTOF-MS/MS based metabolomics and their anti-inflammatory/anti-oxidant activities on RAW264.7 cells Conference paper
Zhao, Mingming, Kinghu, Kegang, Zhao, Guanding, Xiong, Shihang, Ma, Qiushuo, Chen, Qiling, Hua, Tianyi, Yu, Jinyu, Shen, Liyu, Hou, Xiaotao, Hao, Erwei, Du, Zhengcai, Deng, Jiagang, Chen, Xiaojia, Li, Peng, Yu, Hua. Structural characterization and discrimination of three yellow camellia species with UPLC-QTOF-MS/MS based metabolomics and their anti-inflammatory/anti-oxidant activities on RAW264.7 cells[C], Xi'an:The 4th International Symposium on Phytochemicals in Medicine and Food, 2020.
Authors:  Zhao, Mingming;  Kinghu, Kegang;  Zhao, Guanding;  Xiong, Shihang;  Ma, Qiushuo; et al.
Favorite |  | Submit date：2022/08/02
Yellow Camellia Species  Metabolomics  Anti-inflammation  Anti-oxidant  
Comprehensive comparison on the anti-inflammatory effects of three species of Sigesbeckia plants based on NF-kappa B and MAPKs signal pathways in vitro Journal article
Linghu, Ke-Gang, Zhao, Guanding, Xiong, Wei, Sang, Wei, Xiong, Shihang, Tse, Anfernee Kai Wing, Hu, Yuanjia, Bian, Zhaoxiang, Wang, Yitao, Yu, Hua. Comprehensive comparison on the anti-inflammatory effects of three species of Sigesbeckia plants based on NF-kappa B and MAPKs signal pathways in vitro[J]. JOURNAL OF ETHNOPHARMACOLOGY, 2020.
Authors:  Linghu, Ke-Gang;  Zhao, Guanding;  Xiong, Wei;  Sang, Wei;  Xiong, Shihang; et al.
Favorite |   IF:4.8/4.8 | Submit date：2022/08/31