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Discovery of potent LRRK2 inhibitors by ensemble virtual screening strategy and bioactivity evaluation
Journal article
Gong, Xiaoqing, Li, Shuli, Huang, Junli, Tan, Shuoyan, Zhang, Qianqian, Tian, Yanan, Li, Qin, Wang, Lingling, Tong, Henry H.Y., Yao, Xiaojun, Chen, Chunxia, Lee, Simon Ming Yuen, Liu, Huanxiang. Discovery of potent LRRK2 inhibitors by ensemble virtual screening strategy and bioactivity evaluation[J]. European Journal of Medicinal Chemistry, 2024, 279, 116812.
Authors:
Gong, Xiaoqing
;
Li, Shuli
;
Huang, Junli
;
Tan, Shuoyan
;
Zhang, Qianqian
; et al.
Favorite
|
TC[WOS]:
0
TC[Scopus]:
0
IF:
6.0
/
6.1
|
Submit date:2024/10/10
Fingerprint
Lrrk2
Molecular Docking
Pharmacophore
Virtual Screening
Zebrafish
Zeolitic Imidazolate Frameworks Based Anticancer Drug Delivery System Associated with Dual Action of Surface Charge and Lewis Base Ligand
Journal article
Yang, Wenjuan, Tian, Lingling, Zhao, Ning, Feng, Lingyan, Zhou, Bingpu, Zhu, Yongheng, Gao, Xinghua, Zhang, Yuan. Zeolitic Imidazolate Frameworks Based Anticancer Drug Delivery System Associated with Dual Action of Surface Charge and Lewis Base Ligand[J]. Advanced Therapeutics, 2024, 7(9), 2300447.
Authors:
Yang, Wenjuan
;
Tian, Lingling
;
Zhao, Ning
;
Feng, Lingyan
;
Zhou, Bingpu
; et al.
Favorite
|
TC[WOS]:
0
TC[Scopus]:
0
IF:
3.7
/
4.7
|
Submit date:2024/09/03
Cell Cytotoxicity
Cellular Uptake
Drug Delivery
Lewis Basicity
Surface Charge
Zifs
MMP14 (High) macrophages orchestrate progressive pulmonary fibrosis in Sr-Ag-induced hypersensitivity pneumonitis
Journal article
Dan Peng, Li Juan, Li Yin, Bai LingLing, Xiong AnYing, He Xiang, Li XiaoLan, Ran Qin, Zhang Lei, Jiang ManLing, Wang JunYi, Leung Elaine Lai Han, Yang PingChang, Li GuoPing. MMP14 (High) macrophages orchestrate progressive pulmonary fibrosis in Sr-Ag-induced hypersensitivity pneumonitis[J]. Pharmacological Research, 2024.
Authors:
Dan Peng
;
Li Juan
;
Li Yin
;
Bai LingLing
;
Xiong AnYing
; et al.
Adobe PDF
|
Favorite
|
IF:
9.1
/
9.0
|
Submit date:2024/06/10
MMP14high macrophages orchestrate progressive pulmonary fibrosis in SR-Ag-induced hypersensitivity pneumonitis
Journal article
Dan Peng, Li Juan, Li Yin, Bai Lingling, Xiong AnYing, He Xiang, Li XiaoLan, Ran Qin, Zhang Lei, Jiang ManLing, Wang JunYi, Leung Elaine Lai Han, Yang PingChang, Li GuoPing. MMP14high macrophages orchestrate progressive pulmonary fibrosis in SR-Ag-induced hypersensitivity pneumonitis[J]. Pharmacological Research, 2024, 200, 107070.
Authors:
Dan Peng
;
Li Juan
;
Li Yin
;
Bai Lingling
;
Xiong AnYing
; et al.
Favorite
|
TC[WOS]:
2
TC[Scopus]:
1
IF:
9.1
/
9.0
|
Submit date:2024/02/22
Exosome
Fibroblast-to-myofibroblast Transition
Hypersensitivity Pneumonitis
Macrophage
Mmp14
Pulmonary Fibrosis
A DNA-Modularized STING Agonist with Macrophage-Selectivity and Programmability for Enhanced Anti-Tumor Immunotherapy
Journal article
Chen, Yingzhi, Li, Ruike, Duan, Qiao, Wu, Lingling, Li, Xinyi, Luo, Aoxiang, Zhang, Yongming, Zhao, Na, Cui, Kai, Wu, Wenwei, Liu, Tize, Wan, Jian Bo, Deng, Liufu, Li, Guiying, Hou, Lijun, Tan, Weihong, Xiao, Zeyu. A DNA-Modularized STING Agonist with Macrophage-Selectivity and Programmability for Enhanced Anti-Tumor Immunotherapy[J]. Advanced Science, 2024, 11(32).
Authors:
Chen, Yingzhi
;
Li, Ruike
;
Duan, Qiao
;
Wu, Lingling
;
Li, Xinyi
; et al.
Favorite
|
TC[WOS]:
0
TC[Scopus]:
0
IF:
14.3
/
16.3
|
Submit date:2024/07/04
Aptamer
Cancer Immunotherapy
Cgas-sting
Dna Nanotechnology
Drug Delivery
Tumor-associated Macrophages
Ultrathin Cu-TCPP Nanosheet-Based Electrochemical Microsensor for Detecting the Immunosuppressive Drug Mycophenolic Acid
Journal article
Deng, Mingshi, Jin, Wei, Yang, Wenjuan, Tian, Lingling, Gao, Xinghua, Wang, Xuefeng, Feng, Lingyan, Janyasupab, Metini, Zhou, Bingpu, Zhang, Yuan. Ultrathin Cu-TCPP Nanosheet-Based Electrochemical Microsensor for Detecting the Immunosuppressive Drug Mycophenolic Acid[J]. ACS Applied Nano Materials, 2023, 6(24), 22979-22988.
Authors:
Deng, Mingshi
;
Jin, Wei
;
Yang, Wenjuan
;
Tian, Lingling
;
Gao, Xinghua
; et al.
Favorite
|
TC[WOS]:
4
TC[Scopus]:
4
IF:
5.3
/
5.4
|
Submit date:2024/02/22
Catalytic Activity
Cu−tcpp
Electrochemical Microsensor
Immunosuppressive Drugs
Ultrathin Mofs
Chlorpromazine affects autophagy in association with altered Rag GTPase–mTORC1–TFEB signaling
Journal article
Li, Ningning, Rao, Lingling, Zhao, Xueqing, Shen, Junwen, Su, Dan, Ma, Guoqiang, Sun, Shan, Ma, Qilian, Zhang, Li, Dong, Chunsheng, Tam, Kin Yip, Prehn, Jochen H.M., Wang, Hongfeng, Ying, Zheng. Chlorpromazine affects autophagy in association with altered Rag GTPase–mTORC1–TFEB signaling[J]. Frontiers in Cell and Developmental Biology, 2023, 11, 1266198.
Authors:
Li, Ningning
;
Rao, Lingling
;
Zhao, Xueqing
;
Shen, Junwen
;
Su, Dan
; et al.
Favorite
|
TC[WOS]:
0
TC[Scopus]:
0
IF:
4.6
/
5.2
|
Submit date:2024/02/22
Autophagy
Cpz
Mtorc1
Rag Gtpases
Tfeb
Definitive Endodermal Cells Supply an in vitro Source of Mesenchymal Stem/Stromal Cells
Journal article
Yumeng Zhang, Ye Yi, Xia Xiao, Lingling Hu, Jiaqi Xu, Dejin Zheng, Ho Cheng Koc, Un In Chan, Ya Meng, Ligong Lu, Weiwei Liu, Xiaoling Xu, Ningyi Shao, Edwin Chong Wing Cheung, Ren-He Xu, Guokai Chen. Definitive Endodermal Cells Supply an in vitro Source of Mesenchymal Stem/Stromal Cells[J]. Communications Biology, 2023, 6(1), 476.
Authors:
Yumeng Zhang
;
Ye Yi
;
Xia Xiao
;
Lingling Hu
;
Jiaqi Xu
; et al.
Favorite
|
TC[WOS]:
4
TC[Scopus]:
4
IF:
5.2
/
5.6
|
Submit date:2023/08/03
A social exchange perspective on perceived exploitative employment relationship
Project
项目类型: MYRG, 项目编号: MYRG2022-00270-FBA, 资助机构: UM, 2023-2024
Authors:
ZHANG LINGLING
Favorite
|
|
Submit date:2023/03/29
Anti-inflammatory effect of Rhein on ulcerative colitis via inhibiting PI3K/Akt/mTOR signaling pathway and regulating gut microbiota
Journal article
Dong, Lingling, Du, Hongling, Zhang, Minyue, Xu, Haiting, Pu, Xiulan, Chen, Qiyan, Luo, Ruifeng, Hu, Yichen, Wang, Yitao, Tu, He, Zhang, Jinming, Gao, Fei. Anti-inflammatory effect of Rhein on ulcerative colitis via inhibiting PI3K/Akt/mTOR signaling pathway and regulating gut microbiota[J]. Phytotherapy Research, 2022, 36(5), 2081 - 2094.
Authors:
Dong, Lingling
;
Du, Hongling
;
Zhang, Minyue
;
Xu, Haiting
;
Pu, Xiulan
; et al.
Favorite
|
TC[WOS]:
101
TC[Scopus]:
110
IF:
6.1
/
7.0
|
Submit date:2022/05/17
Antiinflammation
Gut Microbiota
Network Pharmacology
Pi3k/akt/mtor Signaling Pathway
Rhein
Ulcerative Colitis