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Discovery of potent LRRK2 inhibitors by ensemble virtual screening strategy and bioactivity evaluation Journal article
Gong, Xiaoqing, Li, Shuli, Huang, Junli, Tan, Shuoyan, Zhang, Qianqian, Tian, Yanan, Li, Qin, Wang, Lingling, Tong, Henry H.Y., Yao, Xiaojun, Chen, Chunxia, Lee, Simon Ming Yuen, Liu, Huanxiang. Discovery of potent LRRK2 inhibitors by ensemble virtual screening strategy and bioactivity evaluation[J]. European Journal of Medicinal Chemistry, 2024, 279, 116812.
Authors:  Gong, Xiaoqing;  Li, Shuli;  Huang, Junli;  Tan, Shuoyan;  Zhang, Qianqian; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:6.0/6.1 | Submit date：2024/10/10
Fingerprint  Lrrk2  Molecular Docking  Pharmacophore  Virtual Screening  Zebrafish  
Drug screening on digital microfluidics for cancer precision medicine Journal article
Zhai, Jiao, Liu, Yingying, Ji, Weiqing, Huang, Xinru, Wang, Ping, Li, Yunyi, Li, Haoran, Wong, Ada Hang Heng, Zhou, Xiong, Chen, Ping, Wang, Lianhong, Yang, Ning, Chen, Chi, Chen, Haitian, Mak, Pui In, Deng, Chu Xia, Martins, Rui, Yang, Mengsu, Ho, Tsung Yi, Yi, Shuhong, Yao, Hailong, Jia, Yanwei. Drug screening on digital microfluidics for cancer precision medicine[J]. Nature Communications, 2024, 15(1), 4363.
Authors:  Zhai, Jiao;  Liu, Yingying;  Ji, Weiqing;  Huang, Xinru;  Wang, Ping; et al.
Favorite | TC[WOS]:4 TC[Scopus]:5  IF:14.7/16.1 | Submit date：2024/06/05
In-vitro  On-chip  Cell  Epirubicin  Breast  Angiogenesis  Glycolysis  Inhibitors  Platform  Feedback  
Variability in SOD1-associated amyotrophic lateral sclerosis: geographic patterns, clinical heterogeneity, molecular alterations, and therapeutic implications Journal article
Huang, Miaodan, Liu, Yong U., Yao, Xiaoli, Qin, Dajiang, Su, Huanxing. Variability in SOD1-associated amyotrophic lateral sclerosis: geographic patterns, clinical heterogeneity, molecular alterations, and therapeutic implications[J]. Translational Neurodegeneration, 2024, 13(1).
Authors:  Huang, Miaodan;  Liu, Yong U.;  Yao, Xiaoli;  Qin, Dajiang;  Su, Huanxing
Favorite | TC[WOS]:1 TC[Scopus]:3  IF:10.8/11.6 | Submit date：2024/09/03
Amyotrophic lateral sclerosis  Genetic therapy  Genotype  Geographic pattern  SOD1 variants  
AQLoRA: An Adaptive Quantization-based Efficient Fine-tuning Method for LLMs Conference paper
Xingchen Huang, Yujia Huo, Derek F. Wong, Yao Wang, Liqiong Cai, Yonghong Jiang. AQLoRA: An Adaptive Quantization-based Efficient Fine-tuning Method for LLMs[C], 2024.
Authors:  Xingchen Huang;  Yujia Huo;  Derek F. Wong;  Yao Wang;  Liqiong Cai; et al.
Favorite |  | Submit date：2024/08/30
E3 ubiquitin ligase UBR5 modulates circadian rhythm by facilitating the ubiquitination and degradation of the key clock transcription factor BMAL1 Journal article
Duan, Chunyan, Li, Yue, Zhi, Haoyu, Tian, Yao, Huang, Zhengyun, Chen, Suping, Zhang, Yang, Liu, Qing, Zhou, Liang, Jiang, Xiaogang, Ullah, Kifayat, Guo, Qing, Liu, Zhaohui, Xu, Ying, Han, Junhai, Hou, Jiajie, O’Connor, Darran P., Xu, Guo qiang. E3 ubiquitin ligase UBR5 modulates circadian rhythm by facilitating the ubiquitination and degradation of the key clock transcription factor BMAL1[J]. ACTA PHARMACOLOGICA SINICA, 2024, 45, 1793-1808.
Authors:  Duan, Chunyan;  Li, Yue;  Zhi, Haoyu;  Tian, Yao;  Huang, Zhengyun; et al.
Favorite | TC[WOS]:2 TC[Scopus]:1  IF:6.9/7.6 | Submit date：2024/06/05
Bmal1  Circadian Rhythm  Proteomics  Transcriptional Activity  Ubiquitination  Ubr5  
Dual inhibitors of DNMT and HDAC remodels the immune microenvironment of colorectal cancer and enhances the efficacy of anti-PD-L1 therapy Journal article
Yang ZhanBo, Chu BiZhu, Tu Yao, Li LuLu, Chen DaWei, Huang ShouHui, Huang WenJun, Fan WeiWen, Li QinYuan, Zhang CunLong, Yuan ZiGao, Huang Jumin, Leung Elaine Lai Han, Jiang Yuyang. Dual inhibitors of DNMT and HDAC remodels the immune microenvironment of colorectal cancer and enhances the efficacy of anti-PD-L1 therapy[J]. Pharmacological Research, 2024, 206, 107271.
Authors:  Yang ZhanBo;  Chu BiZhu;  Tu Yao;  Li LuLu;  Chen DaWei; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:9.1/9.0 | Submit date：2024/06/17
Dnmt  Hdac  Rig-i/mda5-mavs  Anti-pd-l1 Therapy  Tumor Immune Microenvironment  
Longitudinal Associations between Healthy Eating Habits, Resilience, Insomnia, and Internet Addiction in Chinese College Students: A Cross-Lagged Panel Analysis Journal article
Yao, Liqing, Liang, Kaixin, Huang, Liuyue, Xiao, Jialin, Zhou, Kaiji, Chen, Sitong, Chi, Xinli. Longitudinal Associations between Healthy Eating Habits, Resilience, Insomnia, and Internet Addiction in Chinese College Students: A Cross-Lagged Panel Analysis[J]. Nutrients, 2024, 16(15), 2470.
Authors:  Yao, Liqing;  Liang, Kaixin;  Huang, Liuyue;  Xiao, Jialin;  Zhou, Kaiji; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:4.8/5.8 | Submit date：2024/09/03
College Students  Cross-lagged Panel Analysis  Healthy Eating Habits  Insomnia  Internet Addiction  Resilience  
Schizophrenia-Like Behaviors Arising from Dysregulated Proline Metabolism Are Associated with Altered Neuronal Morphology and Function in Mice with Hippocampal PRODH Deficiency Journal article
Yao, Yuxiao, Jin, Chenchen, Liao, Yilie, Huang, Xiang, Wei, Ziying, Zhang, Yahong, Li, Dongwei, Su, Huanxing, Han, Weiping, Qin, Dajiang. Schizophrenia-Like Behaviors Arising from Dysregulated Proline Metabolism Are Associated with Altered Neuronal Morphology and Function in Mice with Hippocampal PRODH Deficiency[J]. Aging and Disease, 2024, 15(4), 1952-1968.
Authors:  Yao, Yuxiao;  Jin, Chenchen;  Liao, Yilie;  Huang, Xiang;  Wei, Ziying; et al.
Favorite | TC[WOS]:1 TC[Scopus]:1  IF:7.0/7.1 | Submit date：2024/09/03
Hippocampus  Metabolism  Neuron  Prodh  Proline  Schizophrenia  
Tanshinone IIA induces ER stress and JNK activation to inhibit tumor growth and enhance anti-PD-1 immunotherapy in non-small cell lung cancer Journal article
Zhang YiZhong, Lai HuanLing, Huang Chen, Jiang ZeBo, Yan HaoXin, Wang XuanRun, Xie Chun, Huang JuMin, Ren WenKang, Li JiaXin, Zhai ZhiRan, Yao XiaoJun, Wu QiBiao, Leung Elaine Lai Han. Tanshinone IIA induces ER stress and JNK activation to inhibit tumor growth and enhance anti-PD-1 immunotherapy in non-small cell lung cancer[J]. Phytomedicine, 2024, 128, 155431.
Authors:  Zhang YiZhong;  Lai HuanLing;  Huang Chen;  Jiang ZeBo;  Yan HaoXin; et al.
Favorite | TC[WOS]:0 TC[Scopus]:1  IF:6.7/6.2 | Submit date：2024/05/16
Er Stress  Jnk  Nfat2  Nsclc  Pd-l1  Tanshinone Iia  
Atomic tailoring-induced deficiency in tungsten oxides for high-performance energy-related devices Review article
2024
Authors:  Lin, Jing Huang;  Yan, Yao Tian;  Qi, Jun Lei;  Zha, Chen Yang
Favorite | TC[WOS]:18 TC[Scopus]:16  IF:5.6/5.5 | Submit date：2024/11/05
Atomic Structures  Catalyst  Oxygen Deficiency  Storage  Tungsten Oxide