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Discovery of potent LRRK2 inhibitors by ensemble virtual screening strategy and bioactivity evaluation
Journal article
Gong, Xiaoqing, Li, Shuli, Huang, Junli, Tan, Shuoyan, Zhang, Qianqian, Tian, Yanan, Li, Qin, Wang, Lingling, Tong, Henry H.Y., Yao, Xiaojun, Chen, Chunxia, Lee, Simon Ming Yuen, Liu, Huanxiang. Discovery of potent LRRK2 inhibitors by ensemble virtual screening strategy and bioactivity evaluation[J]. European Journal of Medicinal Chemistry, 2024, 279, 116812.
Authors:
Gong, Xiaoqing
;
Li, Shuli
;
Huang, Junli
;
Tan, Shuoyan
;
Zhang, Qianqian
; et al.
Favorite
|
TC[WOS]:
0
TC[Scopus]:
0
IF:
6.0
/
6.1
|
Submit date:2024/10/10
Fingerprint
Lrrk2
Molecular Docking
Pharmacophore
Virtual Screening
Zebrafish
Dynamical chiral Nernst effect in twisted Van der Waals few layers
Journal article
Li, Juncheng, Zhai, Dawei, Xiao, Cong, Yao, Wang. Dynamical chiral Nernst effect in twisted Van der Waals few layers[J]. Quantum Frontiers, 2024, 3(1), 11.
Authors:
Li, Juncheng
;
Zhai, Dawei
;
Xiao, Cong
;
Yao, Wang
Favorite
|
TC[Scopus]:
1
|
Submit date:2024/08/05
Ac Out-of-plane Electric Field
Chiral Structure
Nernst Effect
Quantum Geometric Quantity
Twisted Transition Metal Dichalcogenides
Variability in SOD1-associated amyotrophic lateral sclerosis: geographic patterns, clinical heterogeneity, molecular alterations, and therapeutic implications
Journal article
Huang, Miaodan, Liu, Yong U., Yao, Xiaoli, Qin, Dajiang, Su, Huanxing. Variability in SOD1-associated amyotrophic lateral sclerosis: geographic patterns, clinical heterogeneity, molecular alterations, and therapeutic implications[J]. Translational Neurodegeneration, 2024, 13(1).
Authors:
Huang, Miaodan
;
Liu, Yong U.
;
Yao, Xiaoli
;
Qin, Dajiang
;
Su, Huanxing
Favorite
|
TC[WOS]:
2
TC[Scopus]:
3
IF:
10.8
/
11.6
|
Submit date:2024/09/03
Amyotrophic lateral sclerosis
Genetic therapy
Genotype
Geographic pattern
SOD1 variants
Drug screening on digital microfluidics for cancer precision medicine
Journal article
Zhai, Jiao, Liu, Yingying, Ji, Weiqing, Huang, Xinru, Wang, Ping, Li, Yunyi, Li, Haoran, Wong, Ada Hang Heng, Zhou, Xiong, Chen, Ping, Wang, Lianhong, Yang, Ning, Chen, Chi, Chen, Haitian, Mak, Pui In, Deng, Chu Xia, Martins, Rui, Yang, Mengsu, Ho, Tsung Yi, Yi, Shuhong, Yao, Hailong, Jia, Yanwei. Drug screening on digital microfluidics for cancer precision medicine[J]. Nature Communications, 2024, 15(1), 4363.
Authors:
Zhai, Jiao
;
Liu, Yingying
;
Ji, Weiqing
;
Huang, Xinru
;
Wang, Ping
; et al.
Favorite
|
TC[WOS]:
4
TC[Scopus]:
5
IF:
14.7
/
16.1
|
Submit date:2024/06/05
In-vitro
On-chip
Cell
Epirubicin
Breast
Angiogenesis
Glycolysis
Inhibitors
Platform
Feedback
Intrinsic dipole Hall effect in twisted MoTe2: magnetoelectricity and contact-free signatures of topological transitions
Journal article
Fan, Feng Ren, Xiao, Cong, Yao, Wang. Intrinsic dipole Hall effect in twisted MoTe2: magnetoelectricity and contact-free signatures of topological transitions[J]. Nature Communications, 2024, 15(1), 7997.
Authors:
Fan, Feng Ren
;
Xiao, Cong
;
Yao, Wang
Favorite
|
TC[WOS]:
0
TC[Scopus]:
0
IF:
14.7
/
16.1
|
Submit date:2024/10/10
Abrus cantoniensis Hance: Ethnopharmacology, phytochemistry and pharmacology of a promising traditional Chinese medicine
Journal article
Zhang, Guohui, Hao, Erwei, Xiao, Jian, Yao, Chun, Wang, Yitao, Luo, Hua. Abrus cantoniensis Hance: Ethnopharmacology, phytochemistry and pharmacology of a promising traditional Chinese medicine[J]. Journal of Ethnopharmacology, 2024, 334, 118543.
Authors:
Zhang, Guohui
;
Hao, Erwei
;
Xiao, Jian
;
Yao, Chun
;
Wang, Yitao
; et al.
Favorite
|
TC[WOS]:
4
TC[Scopus]:
4
IF:
4.8
/
4.8
|
Submit date:2024/08/05
Abrus Cantoniensis Hance
Bioactive Ingredients
Ethnopharmacology
Pharmacological Mechanisms
Phytochemistry
Isoalantolactone/hydroxamic acid hybrids as potent dual STAT3/HDAC inhibitors and self-assembled nanoparticles for cancer therapy
Journal article
Mo, Hualong, Liu, Jie Ying, Su, Zhengxi, Zhao, Deng Gao, Ma, Yan Yan, Zhang, Kun, Wang, Qi, Fu, Chun, Wang, Yao, Chen, Meiwan, Hu, Burong. Isoalantolactone/hydroxamic acid hybrids as potent dual STAT3/HDAC inhibitors and self-assembled nanoparticles for cancer therapy[J]. European Journal of Medicinal Chemistry, 2024, 277, 116765.
Authors:
Mo, Hualong
;
Liu, Jie Ying
;
Su, Zhengxi
;
Zhao, Deng Gao
;
Ma, Yan Yan
; et al.
Favorite
|
TC[WOS]:
1
TC[Scopus]:
1
IF:
6.0
/
6.1
|
Submit date:2024/09/03
Antitumor
Hdac
Isoalantolactone
Self-assembled Nanoparticles
Stat3
AQLoRA: An Adaptive Quantization-based Efficient Fine-tuning Method for LLMs
Conference paper
Xingchen Huang, Yujia Huo, Derek F. Wong, Yao Wang, Liqiong Cai, Yonghong Jiang. AQLoRA: An Adaptive Quantization-based Efficient Fine-tuning Method for LLMs[C], 2024.
Authors:
Xingchen Huang
;
Yujia Huo
;
Derek F. Wong
;
Yao Wang
;
Liqiong Cai
; et al.
Favorite
|
|
Submit date:2024/08/30
Current status of support for Automated External Defibrillators (AEDs) in public places and factors influencing their use in China: a cross-sectional study
Journal article
Zhou,Zi yun, Zhang,Jin zi, Zhao,Xian qi, Niu,Yu yao, Zhang,Jing bo, Feng,Bojunhao, Ge,Pu, Liu,Xin yi, Zhou,Le Shan, Wu,Yi bo. Current status of support for Automated External Defibrillators (AEDs) in public places and factors influencing their use in China: a cross-sectional study[J]. JOURNAL OF PUBLIC HEALTH-HEIDELBERG, 2024, 32(11), 2105-2120.
Authors:
Zhou,Zi yun
;
Zhang,Jin zi
;
Zhao,Xian qi
;
Niu,Yu yao
;
Zhang,Jing bo
; et al.
Favorite
|
TC[WOS]:
0
TC[Scopus]:
0
IF:
1.9
/
1.7
|
Submit date:2023/08/03
Automated External Defibrillator
Public
Social Support
Family Health
Health Literacy
Modified general splitting method for the split feasibility problem
Journal article
Vong, Seakweng, Yao, Zhongsheng. Modified general splitting method for the split feasibility problem[J]. Journal of Global Optimization, 2024, 90(3), 711-726.
Authors:
Vong, Seakweng
;
Yao, Zhongsheng
Favorite
|
TC[WOS]:
0
TC[Scopus]:
0
IF:
1.3
/
1.8
|
Submit date:2024/08/05
General Splitting Method
Split Feasibility Problem
Alternated Inertia
Strong Convergence