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Cullin-5 deficiency orchestrates the tumor microenvironment to promote mammary tumor development through CREB1-CCL2 signaling Journal article
Chen, Si, Shao, Fangyuan, Zeng, Jianming, Guo, Sen, Wang, Lijian, Sun, Heng, Lei, Josh Haipeng, Lyu, Xueying, Gao, Shuai, Chen, Qiang, Miao, Kai, Xu, Xiaoling, Deng, Chu Xia. Cullin-5 deficiency orchestrates the tumor microenvironment to promote mammary tumor development through CREB1-CCL2 signaling[J]. Science advances, 2023, 9(3).
Authors:  Chen, Si;  Shao, Fangyuan;  Zeng, Jianming;  Guo, Sen;  Wang, Lijian; et al.
Favorite | TC[WOS]:7 TC[Scopus]:7  IF:11.7/13.7 | Submit date：2023/02/08
S100A9-CXCL12 activation in BRCA1-mutant breast cancer promotes an immunosuppressive microenvironment associated with resistance to immunotherapy Journal article
Jianjie Li, Xiaodong Shu, Jun Xu, Sek Man Su, Un In Chan, Lihua Mo, Jianlin Liu, Xin Zhang, Ragini Adhav, Qiang Chen, Yuqing Wang, Tingting An, Xu Zhang, Xueying Lyu, Xiaoling Li, Josh Haipeng Lei, Kai Miao, Heng Sun, Fuqiang Xing, Aiping Zhang, Chuxia Deng, Xiaoling Xu. S100A9-CXCL12 activation in BRCA1-mutant breast cancer promotes an immunosuppressive microenvironment associated with resistance to immunotherapy[J]. Nature Communications, 2022, 13(1), 1481.
Authors:  Jianjie Li;  Xiaodong Shu;  Jun Xu;  Sek Man Su;  Un In Chan; et al.
Favorite | TC[WOS]:37 TC[Scopus]:42  IF:14.7/16.1 | Submit date：2022/05/13
Patient-Derived Organoids Can Guide Personalized-Therapies for Patients with Advanced Breast Cancer Journal article
Ping Chen, Xu Zhang, Renbo Ding, Linglin Yang, Xueying Lyu, Jianming Zeng, Josh Haipeng Lei, Lijian Wang, Jiong Bi, Nan Shao, Ditian Shu, Bin Wu, Jingbo Wu, Zhihui Yang, Haiyan Wang, Biqiong Wang, Kang Xiong, Yun Lu, Shaozhi Fu, Tak Kan Choi, Ng Wai Lon, Aiping Zhang, Dongyang Tang, Yingyao Quan, Ya Meng, Kai Miao, Heng Sun, Ming Zhao, Jiaolin Bao, Lei Zhang, Xiaoling Xu, Yanxia Shi, Ying Lin, Chuxia Deng. Patient-Derived Organoids Can Guide Personalized-Therapies for Patients with Advanced Breast Cancer[J]. Advanced Science, 2021, 8(22), 2101176.
Authors:  Ping Chen;  Xu Zhang;  Renbo Ding;  Linglin Yang;  Xueying Lyu; et al.
Favorite | TC[WOS]:75 TC[Scopus]:77  IF:14.3/16.3 | Submit date：2021/11/30
Advanced Breast Cancer  Drug Screening  Patient-derived Organoids  Personalized Therapy  
Cullin3 deficiency shapes tumor microenvironment and promotes cholangiocarcinoma in liver-specific smad4/pten mutant mice Journal article
Zhao, Ming, Quan, Yingyao, Zeng, Jianming, Lyu, Xueying, Wang, Haitao, Lei, Josh Haipeng, Feng, Yangyang, Xu, Jun, Chen, Qiang, Sun, Heng, Xu, Xiaoling, Lu, Ligong, Deng, Chu Xia. Cullin3 deficiency shapes tumor microenvironment and promotes cholangiocarcinoma in liver-specific smad4/pten mutant mice[J]. International Journal of Biological Sciences, 2021, 17(15), 4176-4191.
Authors:  Zhao, Ming;  Quan, Yingyao;  Zeng, Jianming;  Lyu, Xueying;  Wang, Haitao; et al.
Favorite | TC[WOS]:10 TC[Scopus]:9  IF:8.2/8.3 | Submit date：2022/05/13
Anti-pd1/pd-l1 Therapy  Cholangiocarcinoma  Exhausted t Cells  Inflammatory Cytokines  Tumor Microenvironment  
Accelerating precision anti-cancer therapy by time-lapse and label-free 3D tumor slice culture platform Journal article
Xing, Fuqiang, Liu, Yu Cheng, Huang, Shigao, Lyu, Xueying, Su, Sek Man, Chan, Un In, Wu, Pei Chun, Yan, Yinghan, Ai, Nana, Li, Jianjie, Zhao, Ming, Rajendran, Barani Kumar, Liu, Jianlin, Shao, Fangyuan, Sun, Heng, Choi, Tak Kan, Zhu, Wenli, Luo, Guanghui, Liu, Shuiming, Xu, De Li, Chan, Kin Long, Zhao, Qi, Miao, Kai, Luo, Kathy Qian, Ge, Wei, Xu, Xiaoling, Wang, Guanyu, Liu, Tzu Ming, Deng, Chu Xia. Accelerating precision anti-cancer therapy by time-lapse and label-free 3D tumor slice culture platform[J]. Theranostics, 2021, 11(19), 9415-9430.
Authors:  Xing, Fuqiang;  Liu, Yu Cheng;  Huang, Shigao;  Lyu, Xueying;  Su, Sek Man; et al.
Adobe PDF | Favorite | TC[WOS]:16 TC[Scopus]:18  IF:12.4/12.0 | Submit date：2021/11/30
3d Tumor Slice Culture  Apoptosis  Fret Technique  Label-free  Personalized Medicine  
Molecular landscape and subtype-specific therapeutic response of nasopharyngeal carcinoma revealed by integrative pharmacogenomics Journal article
Ding, Ren Bo, Chen, Ping, Rajendran, Barani Kumar, Lyu, Xueying, Wang, Haitao, Bao, Jiaolin, Zeng, Jianming, Hao, Wenhui, Sun, Heng, Wong, Ada Hang Heng, Valecha, Monica Vishnu, Yang, Eun Ju, Su, Sek Man, Choi, Tak Kan, Liu, Shuiming, Chan, Kin Iong, Yang, Ling Lin, Wu, Jingbo, Miao, Kai, Chen, Qiang, Shim, Joong Sup, Xu, Xiaoling, Deng, Chu Xia. Molecular landscape and subtype-specific therapeutic response of nasopharyngeal carcinoma revealed by integrative pharmacogenomics[J]. Nature Communications, 2021, 12(1), 3046.
Authors:  Ding, Ren Bo;  Chen, Ping;  Rajendran, Barani Kumar;  Lyu, Xueying;  Wang, Haitao; et al.
Favorite | TC[WOS]:53 TC[Scopus]:51  IF:14.7/16.1 | Submit date：2021/11/30
Enhanced Protein Damage Clearance Induces Broad Drug Resistance in Multitype of Cancers Revealed by an Evolution Drug-Resistant Model and Genome-Wide siRNA Screening Journal article
Shao,Fangyuan, Lyu,Xueying, Miao,Kai, Xie,Lisi, Wang,Haitao, Xiao,Hao, Li,Jie, Chen,Qiang, Ding,Renbo, Chen,Ping, Xing,Fuqiang, Zhang,Xu, Luo,Guang Hui, Zhu,Wenli, Cheng,Gregory, Lon,Ng Wai, Martin,Scott E., Wang,Guanyu, Chen,Guokai, Dai,Yunlu, Deng,Chu Xia. Enhanced Protein Damage Clearance Induces Broad Drug Resistance in Multitype of Cancers Revealed by an Evolution Drug-Resistant Model and Genome-Wide siRNA Screening[J]. Advanced Science, 2020, 7(23), 2001914.
Authors:  Shao,Fangyuan;  Lyu,Xueying;  Miao,Kai;  Xie,Lisi;  Wang,Haitao; et al.
Favorite | TC[WOS]:11 TC[Scopus]:12  IF:14.3/16.3 | Submit date：2021/03/02
Characterization of BRCA1-deficient premalignant tissues and cancers identifies Plekha5 as a tumor metastasis suppressor Journal article
Liu,Jianlin, Adhav,Ragini, Miao,Kai, Su,Sek Man, Mo,Lihua, Chan,Un In, Zhang,Xin, Xu,Jun, Li,Jianjie, Shu,Xiaodong, Zeng,Jianming, Zhang,Xu, Lyu,Xueying, Pardeshi,Lakhansing, Tan,Kaeling, Sun,Heng, Wong,Koon Ho, Deng,Chuxia, Xu,Xiaoling. Characterization of BRCA1-deficient premalignant tissues and cancers identifies Plekha5 as a tumor metastasis suppressor[J]. Nature Communications, 2020, 11(1).
Authors:  Liu,Jianlin;  Adhav,Ragini;  Miao,Kai;  Su,Sek Man;  Mo,Lihua; et al.
Favorite | TC[WOS]:23 TC[Scopus]:25  IF:14.7/16.1 | Submit date：2021/03/02
NOTCH1 activation compensates BRCA1 deficiency and promotes triple-negative breast cancer formation Journal article
Miao,Kai, Lei,Josh Haipeng, Valecha,Monica Vishnu, Zhang,Aiping, Xu,Jun, Wang,Lijian, Lyu,Xueying, Chen,Si, Miao,Zhengqiang, Zhang,Xin, Su,Sek Man, Shao,Fangyuan, Rajendran,Barani Kumar, Bao,Jiaolin, Zeng,Jianming, Sun,Heng, Chen,Ping, Tan,Kaeling, Chen,Qiang, Wong,Koon Ho, Xu,Xiaoling, Deng,Chu Xia. NOTCH1 activation compensates BRCA1 deficiency and promotes triple-negative breast cancer formation[J]. Nature Communications, 2020, 11(1), 3256.
Authors:  Miao,Kai;  Lei,Josh Haipeng;  Valecha,Monica Vishnu;  Zhang,Aiping;  Xu,Jun; et al.
Favorite | TC[WOS]:59 TC[Scopus]:68  IF:14.7/16.1 | Submit date：2020/09/16
The metabolic footprint during adipocyte commitment highlights ceramide modulation as an adequate approach for obesity treatment Journal article
Hou,Weilong, Chen,Qiang, Wang,Haitao, Qiu,Pengxiang, Lyu,Xueying, Chen,Weiping, Chua,Melvin L.K., Chinn,Y. Eugene, Deng,Chu Xia, Wang,Ruihong. The metabolic footprint during adipocyte commitment highlights ceramide modulation as an adequate approach for obesity treatment[J]. EBioMedicine, 2020, 51, 102605.
Authors:  Hou,Weilong;  Chen,Qiang;  Wang,Haitao;  Qiu,Pengxiang;  Lyu,Xueying; et al.
Favorite | TC[WOS]:3 TC[Scopus]:4  IF:9.7/9.2 | Submit date：2020/09/16
Adipogenesis  Apoptosis  Ceramide  Epigenetic Modification  Metabolic Landscape  Metabolomics  Obesity