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Leocarpinolide B Attenuates Collagen Type II-Induced Arthritis by Inhibiting DNA Binding Activity of NF-κB Journal article
Linghu, Ke Gang, Zhao, Guan Ding, Zhang, Dai Yan, Xiong, Shi Hang, Wu, Guo Ping, Shen, Li Yu, Cui, Wen Qing, Zhang, Tian, Hu, Yuan Jia, Guo, Bing, Shen, Xiang Chun, Yu, Hua. Leocarpinolide B Attenuates Collagen Type II-Induced Arthritis by Inhibiting DNA Binding Activity of NF-κB[J]. Molecules (Basel, Switzerland), 2023, 28(10), 4241.
Authors:  Linghu, Ke Gang;  Zhao, Guan Ding;  Zhang, Dai Yan;  Xiong, Shi Hang;  Wu, Guo Ping; et al.
Favorite | TC[WOS]:4 TC[Scopus]:4  IF:4.2/4.6 | Submit date：2023/06/05
Leocarpinolide b  Nf-κb P65  Rheumatoid Arthritis  Sesquiterpene Lactone  Synovitis  
The “whole ingredients extract” of Astragali Radix improves the symptoms of dextran sulfate sodium-induced ulcerative colitis in mice through systemic immunomodulation Journal article
Linghu, Ke Gang, Ma, Qiushuo, Xiong, Shi Hang, Zhao, Mingming, Chen, Qiling, Xu, Wen, Chen, Meiwan, Zhang, Jian Ye, Hu, Yuanjia, Xu, Wei, Yu, Hua. The “whole ingredients extract” of Astragali Radix improves the symptoms of dextran sulfate sodium-induced ulcerative colitis in mice through systemic immunomodulation[J]. Chinese Medicine (United Kingdom), 2022, 17(1), 109.
Authors:  Linghu, Ke Gang;  Ma, Qiushuo;  Xiong, Shi Hang;  Zhao, Mingming;  Chen, Qiling; et al.
Favorite | TC[WOS]:3 TC[Scopus]:4  IF:5.3/5.5 | Submit date：2023/01/30
Astragali Radix  Whole Ingredients Extract  Immunomodulation  Ulcerative Colitis  
Delivery of therapeutic small interfering RNA: The current patent-based landscape Journal article
Chen, Yu, Xiong, Shi Hang, Li, Fei, Kong, Xiang Jun, Ouyang, De Fang, Zheng, Ying, Yu, Hua, Hu, Yuan Jia. Delivery of therapeutic small interfering RNA: The current patent-based landscape[J]. Molecular Therapy - Nucleic Acids, 2022, 29, 150-161.
Authors:  Chen, Yu;  Xiong, Shi Hang;  Li, Fei;  Kong, Xiang Jun;  Ouyang, De Fang; et al.
Favorite | TC[WOS]:4 TC[Scopus]:6  IF:6.5/6.7 | Submit date：2023/06/29
Delivery Technology  Patent Landscape  Therapeutic Sirna  
Sigesbeckia orientalis L. Derived Active Fraction Ameliorates Perioperative Neurocognitive Disorders Through Alleviating Hippocampal Neuroinflammation Journal article
Chu, John Man Tak, Abulimiti, Amina, Wong, Brian Shing Hei, Zhao, Guan Ding, Xiong, Shi Hang, Zhao, Ming Ming, Wang, Yingyi, Chen, Ying, Wang, Jiaqi, Zhang, Yan, Chang, Raymond Chuen Chung, Yu, Hua, Wong, Gordon Tin Chun. Sigesbeckia orientalis L. Derived Active Fraction Ameliorates Perioperative Neurocognitive Disorders Through Alleviating Hippocampal Neuroinflammation[J]. Frontiers in Pharmacology, 2022, 13, 846631.
Authors:  Chu, John Man Tak;  Abulimiti, Amina;  Wong, Brian Shing Hei;  Zhao, Guan Ding;  Xiong, Shi Hang; et al.
Favorite | TC[WOS]:10 TC[Scopus]:10  IF:4.4/5.0 | Submit date：2022/05/13
Microglia  Neuroinflammation  Perioperative Neurocognitive Disorders  Sigesbeckia Orientalis l  Surgery  
Brij-functionalized chitosan nanocarrier system enhances the intestinal permeability of P-glycoprotein substrate-like drugs Journal article
Xiong, Wei, Xiong, Shi Hang, Chen, Qi Ling, Linghu, Ke Gang, Zhao, Guan Ding, Chu, John M.T., Wong, Gordon T.C., Li, Juan, Hu, Yuan Jia, Wang, Yi Tao, Yu, Hua. Brij-functionalized chitosan nanocarrier system enhances the intestinal permeability of P-glycoprotein substrate-like drugs[J]. Carbohydrate Polymers, 2021, 266.
Authors:  Xiong, Wei;  Xiong, Shi Hang;  Chen, Qi Ling;  Linghu, Ke Gang;  Zhao, Guan Ding; et al.
Favorite | TC[WOS]:15 TC[Scopus]:18  IF:10.7/10.2 | Submit date：2021/09/13
Berberine  Brij-grafted-chitosan  Diabetic Kidney Disease  Oral Nanocarrier  P-glycoprotein  
Bu-Shen-Fang-Chuan formula attenuates cigarette smoke-induced inflammation by modulating the PI3K/Akt-Nrf2 and NF-κB signalling pathways Journal article
Li,Qiuping, Wang,Guifang, Xiong,Shi Hang, Cao,Yuxue, Liu,Baojun, Sun,Jing, Li,Lulu, Mohammadtursun,Nabijan, Yu,Hua, Dong,Jingcheng, Wu,Jinfeng. Bu-Shen-Fang-Chuan formula attenuates cigarette smoke-induced inflammation by modulating the PI3K/Akt-Nrf2 and NF-κB signalling pathways[J]. Journal of Ethnopharmacology, 2020, 261, 113095.
Authors:  Li,Qiuping;  Wang,Guifang;  Xiong,Shi Hang;  Cao,Yuxue;  Liu,Baojun; et al.
Favorite | TC[WOS]:17 TC[Scopus]:18  IF:4.8/4.8 | Submit date：2021/03/02
Bu-shen-fang-chuan Formula (Bsfcf)  Copd  Inflammation  Nrf2  Pi3k/akt  
Sigesbeckia orientalis L. Extract Alleviated the Collagen Type II–Induced Arthritis Through Inhibiting Multi-Target–Mediated Synovial Hyperplasia and Inflammation Journal article
Linghu,Ke Gang, Xiong,Shi Hang, Zhao,Guan Ding, Zhang,Tian, Xiong,Wei, Zhao,Mingming, Shen,Xiang Chun, Xu,Wei, Bian,Zhaoxiang, Wang,Yitao, Yu,Hua. Sigesbeckia orientalis L. Extract Alleviated the Collagen Type II–Induced Arthritis Through Inhibiting Multi-Target–Mediated Synovial Hyperplasia and Inflammation[J]. Frontiers in Pharmacology, 2020, 11, 547913.
Authors:  Linghu,Ke Gang;  Xiong,Shi Hang;  Zhao,Guan Ding;  Zhang,Tian;  Xiong,Wei; et al.
Favorite | TC[WOS]:16 TC[Scopus]:15  IF:4.4/5.0 | Submit date：2021/03/02
Inflammation  Mh7a  Rheumatoid Arthritis  Sigesbeckia Orientalisl  Sw982  Synovial Hyperplasia  
Sigesbeckia glabrescens Makino extract attenuated the collagen-induced arthritis through inhibiting the synovial hyperplasia and inflammation Journal article
Ma,Qiu Shuo, Linghu,Ke Gang, Zhang,Tian, Zhao,Guan Ding, Xiong,Wei, Xiong,Shi Hang, Zhao,Mingming, Xu,Wei, Yu,Juan, Yu,Hua. Sigesbeckia glabrescens Makino extract attenuated the collagen-induced arthritis through inhibiting the synovial hyperplasia and inflammation[J]. Chinese Medicine, 2020, 15(1), 91.
Authors:  Ma,Qiu Shuo;  Linghu,Ke Gang;  Zhang,Tian;  Zhao,Guan Ding;  Xiong,Wei; et al.
Favorite | TC[WOS]:2 TC[Scopus]:3  IF:5.3/5.5 | Submit date：2021/03/02
Inflammation  Nuclear Transcription Factor-kappa b  Rheumnnatoid Arthritis  Sigesbeckia Glabrescens Makino  Sw982  Synovial Hyperplasia  
Comprehensive comparison on the anti-inflammatory effects of three species of Sigesbeckia plants based on NF-κB and MAPKs signal pathways in vitro Journal article
Linghu,Ke Gang, Zhao,Guan Ding, Xiong,Wei, Sang,Wei, Xiong,Shi Hang, Tse,Anfernee Kai Wing, Hu,Yuanjia, Bian,Zhaoxiang, Wang,Yitao, Yu,Hua. Comprehensive comparison on the anti-inflammatory effects of three species of Sigesbeckia plants based on NF-κB and MAPKs signal pathways in vitro[J]. JOURNAL OF ETHNOPHARMACOLOGY, 2020, 250, 112530.
Authors:  Linghu,Ke Gang;  Zhao,Guan Ding;  Xiong,Wei;  Sang,Wei;  Xiong,Shi Hang; et al.
Favorite | TC[WOS]:18 TC[Scopus]:18  IF:4.8/4.8 | Submit date：2021/03/01
Anti-inflammation  Mapks  Nf-κb  Sigesbeckia Glabrescens Makino  Sigesbeckia OrientaL.s L.  Sigesbeckia Pubescens Makino  
Deciphering the Pharmacological Mechanisms of the Huayu-Qiangshen-Tongbi Formula Through Integrating Network Pharmacology and In Vitro Pharmacological Investigation Journal article
Zihao Wang, Ke-Gang Linghu, Yuanjia Hu, Huali Zuo, Hao Yi, Shi-Hang Xiong, Jinjian Lu, Ging Chan, Hua Yu, Run-Yue Huang. Deciphering the Pharmacological Mechanisms of the Huayu-Qiangshen-Tongbi Formula Through Integrating Network Pharmacology and In Vitro Pharmacological Investigation[J]. FRONTIERS IN PHARMACOLOGY, 2019, 10.
Authors:  Zihao Wang;  Ke-Gang Linghu;  Yuanjia Hu;  Huali Zuo;  Hao Yi; et al.
Favorite | TC[WOS]:20 TC[Scopus]:20  IF:4.4/5.0 | Submit date：2019/12/04
Rheumatoid Arthritis  Network Pharmacology  Traditional Chinese Medicine  Huayu-qiangshen-tongbi Formula  In Vitro Validation