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An Hsp70 promoter–based mouse for heat shock–induced gene modulation Journal article
Chen, Hangang, Xie, Yangli, Zhang, Mei, Huang, Junlan, Jiang, Wanling, Zhang, Ruobin, Li, Can, Du, Xiaolan, Chen, Hua, Nie, Qiang, Liang, Sen, Tan, Qiaoyan, Yang, Jing, Jin, Min, Huang, Shuo, Kuang, Liang, Su, Nan, Qi, Huabing, Luo, Xiaoqing, Xu, Xiaoling, Deng, Chuxia, Chen, Lin, Luo, Fengtao. An Hsp70 promoter–based mouse for heat shock–induced gene modulation[J]. Journal of Molecular Medicine, 2024, 102(5), 693-707.
Authors:  Chen, Hangang;  Xie, Yangli;  Zhang, Mei;  Huang, Junlan;  Jiang, Wanling; et al.
Favorite | TC[WOS]:1 TC[Scopus]:1  IF:4.8/4.7 | Submit date：2024/05/16
Cre/loxp System  Gene Modulation  Heat Shock  Hsp70 Promoter  Mouse Model  
Expansion of FGFR3-positive nucleus pulposus cells plays important roles in postnatal nucleus pulposus growth and regeneration Journal article
Xu, Meng, Huang, Junlan, Jin, Min, Jiang, Wanling, Luo, Fengtao, Tan, Qiaoyan, Zhang, Ruobin, Luo, Xiaoqing, Kuang, Liang, Zhang, Dali, Liang, Sen, Qi, Huabing, Chen, Hangang, Ni, Zhenhong, Su, Nan, Yang, Jing, Du, Xiaolan, Chen, Bo, Deng, Chuxia, Xie, Yangli, Chen, Lin. Expansion of FGFR3-positive nucleus pulposus cells plays important roles in postnatal nucleus pulposus growth and regeneration[J]. Stem Cell Research & Therapy, 2022, 13, 227.
Authors:  Xu, Meng;  Huang, Junlan;  Jin, Min;  Jiang, Wanling;  Luo, Fengtao; et al.
Favorite | TC[WOS]:3 TC[Scopus]:3  IF:7.1/7.9 | Submit date：2022/08/02
Intervertebral Disc Degeneration  Nucleus Pulposus  Cell Proliferation  Fgfr3  Genetic Mouse Models  
Inhibition of aberrant Hif1α activation delays intervertebral disc degeneration in adult mice Journal article
Wang, Zuqiang, Chen, Hangang, Tan, Qiaoyan, Huang, Junlan, Zhou, Siru, Luo, Fengtao, Zhang, Dali, Yang, Jing, Li, Can, Chen, Bo, Sun, Xianding, Kuang, Liang, Jiang, Wanling, Ni, Zhenhong, Wang, Quan, Chen, Shuai, Du, Xiaolan, Chen, Di, Deng, Chuxia, Yin, Liangjun, Chen, Lin, Xie, Yangli. Inhibition of aberrant Hif1α activation delays intervertebral disc degeneration in adult mice[J]. Bone Research, 2022, 10(1), 2.
Authors:  Wang, Zuqiang;  Chen, Hangang;  Tan, Qiaoyan;  Huang, Junlan;  Zhou, Siru; et al.
Favorite | TC[WOS]:11 TC[Scopus]:12  IF:14.3/14.8 | Submit date：2022/05/13
Dstyk mutation leads to congenital scoliosis-like vertebral malformations in zebrafish via dysregulated mTORC1/TFEB pathway Journal article
Sun,Xianding, Zhou,Yang, Zhang,Ruobin, Wang,Zuqiang, Xu,Meng, Zhang,Dali, Huang,Junlan, Luo,Fengtao, Li,Fangfang, Ni,Zhenhong, Zhou,Siru, Chen,Hangang, Chen,Shuai, Chen,Liang, Du,Xiaolan, Chen,Bo, Huang,Haiyang, Liu,Peng, Yin,Liangjun, Qiu,Juhui, Chen,Di, Deng,Chuxia, Xie,Yangli, Luo,Lingfei, Chen,Lin. Dstyk mutation leads to congenital scoliosis-like vertebral malformations in zebrafish via dysregulated mTORC1/TFEB pathway[J]. Nature Communications, 2020, 11(1), 479.
Authors:  Sun,Xianding;  Zhou,Yang;  Zhang,Ruobin;  Wang,Zuqiang;  Xu,Meng; et al.
Favorite | TC[WOS]:32 TC[Scopus]:36  IF:14.7/16.1 | Submit date：2020/09/16
FGFR3 deficiency enhances CXCL12-dependent chemotaxis of macrophages via upregulating CXCR7 and aggravates joint destruction in mice Journal article
Kuang,Liang, Wu,Jiangyi, Su,Nan, Qi,Huabing, Chen,Hangang, Zhou,Siru, Xiong,Yan, Du,Xiaolan, Tan,Qiaoyan, Yang,Jing, Jin,Min, Luo,Fengtao, Ouyang,Junjie, Zhang,Bin, Wang,Zuqiang, Jiang,Wanling, Chen,Liang, Chen,Shuai, Wang,Ziming, Liu,Peng, Yin,Liangjun, Guo,Fengjin, Deng,Chuxia, Chen,Di, Liu,Chuanju, Xie,Yangli, Ni,Zhenhong, Chen,Lin. FGFR3 deficiency enhances CXCL12-dependent chemotaxis of macrophages via upregulating CXCR7 and aggravates joint destruction in mice[J]. ANNALS OF THE RHEUMATIC DISEASES, 2020, 79(1), 112-122.
Authors:  Kuang,Liang;  Wu,Jiangyi;  Su,Nan;  Qi,Huabing;  Chen,Hangang; et al.
Favorite | TC[WOS]:43 TC[Scopus]:46  IF:20.3/18.4 | Submit date：2020/09/16
Arthritis  Chemokines  Inflammation  Synovitis  
Rmrp Mutation Disrupts Chondrogenesis and Bone Ossification in Zebrafish Model of Cartilage-Hair Hypoplasia via Enhanced Wnt/β-Catenin Signaling Journal article
Sun,Xianding, Zhang,Ruobin, Liu,Mi, Chen,Hangang, Chen,Liang, Luo,Fengtao, Zhang,Dali, Huang,Junlan, Li,Fangfang, Ni,Zhenhong, Qi,Huabing, Su,Nan, Jin,Min, Yang,Jing, Tan,Qiaoyan, Du,Xiaolan, Chen,Bo, Huang,Haiyang, Chen,Shuai, Yin,Liangjun, Xu,Xiaoling, Deng,Chuxia, Luo,Lingfei, Xie,Yangli, Chen,Lin. Rmrp Mutation Disrupts Chondrogenesis and Bone Ossification in Zebrafish Model of Cartilage-Hair Hypoplasia via Enhanced Wnt/β-Catenin Signaling[J]. Journal of Bone and Mineral Research, 2019, 34(11), 2101-2116.
Authors:  Sun,Xianding;  Zhang,Ruobin;  Liu,Mi;  Chen,Hangang;  Chen,Liang; et al.
Favorite | TC[WOS]:14 TC[Scopus]:17  IF:5.1/5.8 | Submit date：2020/09/16
Cartilage-hair Hypoplasia  Rmrp  Skeletal Development  Wnt/β-catenin  Zebrafish  Beta-catenin  
Adeno-Associated Virus-Mediated RNAi against Mutant Alleles Attenuates Abnormal Calvarial Phenotypes in an Apert Syndrome Mouse Model Journal article
Luo,Fengtao, Xie,Yangli, Wang,Zuqiang, Huang,Junlan, Tan,Qiaoyan, Sun,Xianding, Li,Fangfang, Li,Can, Liu,Mi, Zhang,Dali, Xu,Meng, Su,Nan, Ni,Zhenhong, Jiang,Wanling, Chang,Jinhong, Chen,Hangang, Chen,Shuai, Xu,Xiaoling, Deng,Chuxia, Wang,Zhugang, Du,Xiaolan, Chen,Lin. Adeno-Associated Virus-Mediated RNAi against Mutant Alleles Attenuates Abnormal Calvarial Phenotypes in an Apert Syndrome Mouse Model[J]. Molecular Therapy - Nucleic Acids, 2018, 13, 291-302.
Authors:  Luo,Fengtao;  Xie,Yangli;  Wang,Zuqiang;  Huang,Junlan;  Tan,Qiaoyan; et al.
Favorite | TC[WOS]:14 TC[Scopus]:13  IF:6.5/6.7 | Submit date：2020/09/16
Adeno-associated Virus  Apert Syndrome  Craniosynostosis  Fgfr2  Molecular Therapy  Rnai  
A novel FGFR1-binding peptide exhibits anti-tumor effect on lung cancer by inhibiting proliferation and angiogenesis Journal article
Tan, Qiaoyan, Wang, Zuqiang, Wang, Quan, Wang, Yuanqiang, Huang, Zhifeng, Su, Nan, Jin, Min, Kuang, Liang, Qi, Huabing, Ni, Zhenhong, Li, Can, Zhu, Ying, Jiang, Wanling, Chen, Hangang, Deng, Chuxia, Du, Xiaolan, Xie, Yangli, Chen, Lin. A novel FGFR1-binding peptide exhibits anti-tumor effect on lung cancer by inhibiting proliferation and angiogenesis[J]. INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2018, 14(10), 1389-1398.
Authors:  Tan, Qiaoyan;  Wang, Zuqiang;  Wang, Quan;  Wang, Yuanqiang;  Huang, Zhifeng; et al.
Favorite | TC[WOS]:14 TC[Scopus]:15  IF:8.2/8.3 | Submit date：2018/10/30
Phage Display  Fgfr1  Peptide  Cancer Therapy  Lung Cancer  
Postnatal deletion of Alk5 gene in meniscal cartilage accelerates age-dependent meniscal degeneration in mice Journal article
Wang,Quan, Tan,Qiaoyan, Xu,Wei, Kuang,Liang, Zhang,Bin, Wang,Zuqiang, Ni,Zhenhong, Su,Nan, Jin,Min, Li,Can, Jiang,Wanling, Huang,Junlan, Li,Fangfang, Zhu,Ying, Chen,Hangang, Du,Xiaolan, Chen,Di, Deng,Chuxia, Qi,Huabing, Xie,Yangli, Chen,Lin. Postnatal deletion of Alk5 gene in meniscal cartilage accelerates age-dependent meniscal degeneration in mice[J]. Journal of Cellular Physiology, 2018, 234(1), 595-605.
Authors:  Wang,Quan;  Tan,Qiaoyan;  Xu,Wei;  Kuang,Liang;  Zhang,Bin; et al.
Favorite | TC[WOS]:6 TC[Scopus]:5  IF:4.5/5.3 | Submit date：2020/09/16
Activing Receptor-like Kinases 5 (Alk5)  Matrix Degradation  Meniscal Degeneration  Transforming Growth Factor-β (Tgf-β) Signaling  
Inducible Activation of FGFR2 in Adult Mice Promotes Bone Formation After Bone Marrow Ablation Journal article
Xu, Wei, Luo, Fengtao, Wang, Quan, Tan, Qiaoyan, Huang, Junlan, Zhou, Siru, Wang, Zuqiang, Sun, Xianding, Kuang, Liang, Jin, Min, Su, Nan, Jiang, Wanling, Chen, Liang, Qi, Huabing, Zhu, Ying, Chen, Bo, Chen, Hangang, Chen, Shuai, Gao, Yu, Xu, Xiaoling, Deng, Chuxia, Chen, Lin, Xie, Yangli, Du, Xiaolan. Inducible Activation of FGFR2 in Adult Mice Promotes Bone Formation After Bone Marrow Ablation[J]. JOURNAL OF BONE AND MINERAL RESEARCH, 2017, 32(11), 2194-2206.
Authors:  Xu, Wei;  Luo, Fengtao;  Wang, Quan;  Tan, Qiaoyan;  Huang, Junlan; et al.
Favorite | TC[WOS]:15 TC[Scopus]:14  IF:5.1/5.8 | Submit date：2018/10/30
Bone Marrow Ablation  Fgfr2  Bone Formation  Wnt/beta-catenin