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Global Patent Landscape of Benign Prostatic Hyperplasia Drugs Journal article
Liu, Kunmeng, Yang, Jing, Deng, Jian, Fan, Xiaohui, Hu, Yuanjia. Global Patent Landscape of Benign Prostatic Hyperplasia Drugs[J]. Urology, 2022.
Authors:  Liu, Kunmeng;  Yang, Jing;  Deng, Jian;  Fan, Xiaohui;  Hu, Yuanjia
Favorite | TC[WOS]:1 TC[Scopus]:1  IF:2.1/2.2 | Submit date：2022/05/17
Transcription in fungal conidia before dormancy produces phenotypically variable conidia that maximize survival in different environments Journal article
Wang, Fang, Sethiya, Pooja, Hu, Xiaohui, Guo, Shuhui, Chen, Yingying, Li, Ang, Tan, Kaeling, Wong, Koon Ho. Transcription in fungal conidia before dormancy produces phenotypically variable conidia that maximize survival in different environments[J]. Nature Microbiology, 2021, 6(8), 1066-1081.
Authors:  Wang, Fang;  Sethiya, Pooja;  Hu, Xiaohui;  Guo, Shuhui;  Chen, Yingying; et al.
Favorite | TC[WOS]:42 TC[Scopus]:51  IF:20.5/21.0 | Submit date：2021/12/08
Reinforcement Learning Enabled Dynamic Resource Allocation in the Internet of Vehicles Journal article
Liang, Hongbin, Zhang, Xiaohui, Hong, Xintao, Zhang, Zongyuan, Li, Mushu, Hu, Guangdi, Hou, Fen. Reinforcement Learning Enabled Dynamic Resource Allocation in the Internet of Vehicles[J]. IEEE Transactions on Industrial Informatics, 2021, 17(7), 4957-4967.
Authors:  Liang, Hongbin;  Zhang, Xiaohui;  Hong, Xintao;  Zhang, Zongyuan;  Li, Mushu; et al.
Favorite | TC[WOS]:28 TC[Scopus]:37  IF:11.7/11.4 | Submit date：2021/12/08
Hierarchical Architecture  Internet Of Vehicles (Iov)  Reinforcement Learning  Resource Allocation  Semi-markov Decision Process (Smdp)  
Combined use of arginase and dichloroacetate exhibits anti-proliferative effects in triple negative breast cancer cells Journal article
Angela Verma, Yau-Min Lam, Yun-Chung Leung, Xiaohui Hu, Xin Chen, Edwin Cheung, Kin Yip Tam. Combined use of arginase and dichloroacetate exhibits anti-proliferative effects in triple negative breast cancer cells[J]. JOURNAL OF PHARMACY AND PHARMACOLOGY, 2019, 71(3), 306-315.
Authors:  Angela Verma;  Yau-Min Lam;  Yun-Chung Leung;  Xiaohui Hu;  Xin Chen; et al.
Favorite | TC[WOS]:18 TC[Scopus]:18  IF:2.8/3.8 | Submit date：2020/05/21
Bacillus Caldovelox Arginase  Breast Cancer  Dichloroacetate  Drug Combination  Pegyated Human Arginase  
Dichloroacetophenones targeting at pyruvate dehydrogenase kinase 1 with improved selectivity and antiproliferative activity: Synthesis and structure-activity relationships Journal article
Zhang,Shao Lin, Yang,Zheng, Hu,Xiaohui, Tam,Kin Yip. Dichloroacetophenones targeting at pyruvate dehydrogenase kinase 1 with improved selectivity and antiproliferative activity: Synthesis and structure-activity relationships[J]. Bioorganic and Medicinal Chemistry Letters, 2018, 28(21), 3441-3445.
Authors:  Zhang,Shao Lin;  Yang,Zheng;  Hu,Xiaohui;  Tam,Kin Yip
Favorite | TC[WOS]:16 TC[Scopus]:16  IF:2.5/2.4 | Submit date：2021/03/04
Antiproliferative Activity  Dichloroacetophenone  Kinase Inhibition  Pyruvate Dehydrogenase Complex  Pyruvate Dehydrogenase Kinase  
Dichloroacetophenones targeting at pyruvate dehydrogenase kinase 1 with improved selectivity and antiproliferative activity: Synthesis and structure-activity relationships Journal article
Zhang, Shao-Lin, Yang, Zheng, Hu, Xiaohui, Tam, Kin Yip. Dichloroacetophenones targeting at pyruvate dehydrogenase kinase 1 with improved selectivity and antiproliferative activity: Synthesis and structure-activity relationships[J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 28(21), 3441-3445.
Authors:  Zhang, Shao-Lin;  Yang, Zheng;  Hu, Xiaohui;  Tam, Kin Yip
Favorite | TC[WOS]:16 TC[Scopus]:16  IF:2.5/2.4 | Submit date：2018/10/30
Pyruvate Dehydrogenase Kinase  Pyruvate Dehydrogenase Complex  Antiproliferative Activity  Dichloroacetophenone  Kinase Inhibition  
Inhibition of pyruvate dehydrogenase kinase 1 enhances the anti-cancer effect of EGFR tyrosine kinase inhibitors in non-small cell lung cancer Journal article
Yang, Zheng, Zhang, Shao-Lin, Hu, Xiaohui, Tam, Kin Yip. Inhibition of pyruvate dehydrogenase kinase 1 enhances the anti-cancer effect of EGFR tyrosine kinase inhibitors in non-small cell lung cancer[J]. EUROPEAN JOURNAL OF PHARMACOLOGY, 2018, 838, 41-52.
Authors:  Yang, Zheng;  Zhang, Shao-Lin;  Hu, Xiaohui;  Tam, Kin Yip
Favorite | TC[WOS]:27 TC[Scopus]:27  IF:4.2/4.3 | Submit date：2018/10/30
Dichloroacetophenone  Epidermal Growth Factor Receptor  Tyrosine Kinase Inhibitor  Synergism  Hypoxia  Oxidative Phosphorylation  
Anticancer effects of some novel dichloroacetophenones through the inhibition of pyruvate dehydrogenase kinase 1 Journal article
Zhang, Shao-Lin, Yang, Zheng, Hu, Xiaohui, Chakravarty, Harapriya, Tam, Kin Yip. Anticancer effects of some novel dichloroacetophenones through the inhibition of pyruvate dehydrogenase kinase 1[J]. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2018, 123, 43-55.
Authors:  Zhang, Shao-Lin;  Yang, Zheng;  Hu, Xiaohui;  Chakravarty, Harapriya;  Tam, Kin Yip
Favorite | TC[WOS]:15 TC[Scopus]:15  IF:4.3/4.2 | Submit date：2018/10/30
Dichloroacetophenone  Pyruvate Dehydrogenase Kinase  Pyruvate Dehydrogenase Complex  Anticancer Activity  Metabolic Reprogramming  
Liquid Chromatography-Tandem Mass Spectrometry Method Revealed that Lung Cancer Cells Exhibited Distinct Metabolite Profiles upon the Treatment with Different Pyruvate Dehydrogenase Kinase Inhibitors Journal article
Zhang, Wen, Hu, Xiaohui, Zhou, Wei, Tam, Kin Yip. Liquid Chromatography-Tandem Mass Spectrometry Method Revealed that Lung Cancer Cells Exhibited Distinct Metabolite Profiles upon the Treatment with Different Pyruvate Dehydrogenase Kinase Inhibitors[J]. JOURNAL OF PROTEOME RESEARCH, 2018, 17(9), 3012-3021.
Authors:  Zhang, Wen;  Hu, Xiaohui;  Zhou, Wei;  Tam, Kin Yip
Favorite | TC[WOS]:18 TC[Scopus]:18  IF:3.8/4.1 | Submit date：2018/10/30
Aerobic Glycolysis  Azd7545  Dichloroacetate  Lc-ms/ms  Pyruvate Dehydrogenase Kinases  Cancer Metabolism  
Synthesis and biological evaluation of (R)-3,3,3-trifluoro-2-hydroxy-2methylpropionamides as pyruvate dehydrogenase kinase 1 (PDK1) inhibitors to reduce the growth of cancer cells Conference paper
Zhang, Shao-Lin, Zhang, Wen, Yang, Zheng, Hu, Xiaohui, Tam, Kin Yip. Synthesis and biological evaluation of (R)-3,3,3-trifluoro-2-hydroxy-2methylpropionamides as pyruvate dehydrogenase kinase 1 (PDK1) inhibitors to reduce the growth of cancer cells[C], PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS:ELSEVIER SCIENCE BV, 2017, 87-92.
Authors:  Zhang, Shao-Lin;  Zhang, Wen;  Yang, Zheng;  Hu, Xiaohui;  Tam, Kin Yip
Favorite | TC[WOS]:7 TC[Scopus]:7 | Submit date：2018/10/30
Pyruvate Dehydrogenase Kinase  Pyruvate Dehydrogenase Complex  Anti-proliferation  Binding Affinity