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Probing the AFF4–CCNT1 protein–protein interaction using a metal–organic conjugate for treating triple-negative breast cancer Journal article
Song, Ying Qi, Xu, Yiwen, Yang, Li Jun, Wang, Ling, Jing, Shaozhen, Yang, Guan Jun, Shiu-Hin Chan, Daniel, Wong, Chun Yuen, Wang, Wanhe, Kam Wai Wong, Vincent, Leung, Chung Hang. Probing the AFF4–CCNT1 protein–protein interaction using a metal–organic conjugate for treating triple-negative breast cancer[J]. Chemical Engineering Journal, 2024, 496, 153685.
Authors:  Song, Ying Qi;  Xu, Yiwen;  Yang, Li Jun;  Wang, Ling;  Jing, Shaozhen; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:13.3/13.2 | Submit date：2024/08/05
Aff4  Ccnt1  Metal–organic Conjugate  Protein–protein Interaction  Triple-negative Breast Cancer  
Probing the AFF4-CCNT1 protein-protein interaction using a metal-organic conjugate for treating triple-negative breast cancer Journal article
Ying-Qi Song, Yiwen Xu, Li-Jun Yang, Ling Wang, Zhao Zhen Jing, Guan-Jun Yang, Daniel Shiu-Hin Chan, Chun-Yuen Wong, Wanhe Wang, Vincent Kam Wai Wong, Chung-Hang Leung. Probing the AFF4-CCNT1 protein-protein interaction using a metal-organic conjugate for treating triple-negative breast cancer[J]. Chemical Engineering Journal, 2024, 496, 153685.
Authors:  Ying-Qi Song;  Yiwen Xu;  Li-Jun Yang;  Ling Wang;  Zhao Zhen Jing; et al.
Favorite |   IF:13.3/13.2 | Submit date：2024/08/30
Development of a dual targeting scaffold of SET7/MLL inhibitor for castration-resistant prostate cancer treatment Journal article
Li,Guodong, Huang,Qi, Wai Wong,Vincent Kam, Wang,Wanhe, Leung,Chung Hang. Development of a dual targeting scaffold of SET7/MLL inhibitor for castration-resistant prostate cancer treatment[J]. Genes and Diseases, 2023, 10(6), 2260 - 2262.
Authors:  Li,Guodong;  Huang,Qi;  Wai Wong,Vincent Kam;  Wang,Wanhe;  Leung,Chung Hang
Favorite | TC[WOS]:3 TC[Scopus]:4  IF:6.9/7.2 | Submit date：2023/08/03
A robust luminescent assay for screening alkyladenine DNA glycosylase inhibitors to overcome DNA repair and temozolomide drug resistance Journal article
Song,Ying Qi, Li,Guo Dong, Niu,Dou, Chen,Feng, Jing,Shaozhen, Wai Wong,Vincent Kam, Wang,Wanhe, Leung,Chung Hang. A robust luminescent assay for screening alkyladenine DNA glycosylase inhibitors to overcome DNA repair and temozolomide drug resistance[J]. Journal of Pharmaceutical Analysis, 2023, 13(5), 514-522.
Authors:  Song,Ying Qi;  Li,Guo Dong;  Niu,Dou;  Chen,Feng;  Jing,Shaozhen; et al.
Favorite | TC[WOS]:4 TC[Scopus]:4  IF:6.1/6.8 | Submit date：2023/08/03
Alkyladenine Dna Glycosylase  Drug Screening  Glioblastoma  N3-methyladenine  Sunitinib  Temozolomide  
The role of non-coding RNAs (miRNA and lncRNA) in the clinical management of rheumatoid arthritis Journal article
Yang, Jiujie, Li, Zhi, Wang, Linna, Yun, Xiaoyun, Zeng, Yaling, Ng, Jerome P.L., Lo, Hanghong, Wang, Yan, Zhang, Kaixi, Law, Betty Yuen Kwan, Wong, Vincent Kam Wai. The role of non-coding RNAs (miRNA and lncRNA) in the clinical management of rheumatoid arthritis[J]. Pharmacological Research, 2022, 186.
Authors:  Yang, Jiujie;  Li, Zhi;  Wang, Linna;  Yun, Xiaoyun;  Zeng, Yaling; et al.
Favorite | TC[WOS]:21 TC[Scopus]:17  IF:9.1/9.0 | Submit date：2023/01/30
Clinical Management  Non-coding Rna (ncRna)  Rheumatoid Arthritis (Ra)  
Combining computational and experimental evidence on the activity of antimalarial drugs on papain-like protease of SARS-CoV-2: A repurposing study Journal article
Ribaudo, Giovanni, Yun, Xiaoyun, Ongaro, Alberto, Oselladore, Erika, Ng, Jerome P L., Haynes, Richard K., Law, Betty Yuen Kwan, Memo, Maurizio, Wong, Vincent Kam Wai, Coghi, Paolo, Gianoncelli, Alessandra. Combining computational and experimental evidence on the activity of antimalarial drugs on papain-like protease of SARS-CoV-2: A repurposing study[J]. Chemical Biology and Drug Design, 2022.
Authors:  Ribaudo, Giovanni;  Yun, Xiaoyun;  Ongaro, Alberto;  Oselladore, Erika;  Ng, Jerome P L.; et al.
Favorite | TC[WOS]:3 TC[Scopus]:3  IF:3.2/2.9 | Submit date：2023/01/30
Antimalarial Drugs  Drug Repurposing  Papain-like Protease  Pl-pro  Sars-cov-2  
Antimalarial and Anticancer Activity Evaluation of Bridged Ozonides, Aminoperoxides, and Tetraoxanes Journal article
Coghi, Paolo, Yaremenko, Ivan A., Prommana, Parichat, Wu, Jia Ning, Zhang, Rui Long, Ng, Jerome P.L., Belyakova, Yulia Yu, Law, Betty Yuen Kwan, Radulov, Peter S., Uthaipibull, Chairat, Wong, Vincent Kam Wai, Terent'ev, Alexander O.. Antimalarial and Anticancer Activity Evaluation of Bridged Ozonides, Aminoperoxides, and Tetraoxanes[J]. ChemMedChem, 2022, 17(20).
Authors:  Coghi, Paolo;  Yaremenko, Ivan A.;  Prommana, Parichat;  Wu, Jia Ning;  Zhang, Rui Long; et al.
Favorite | TC[WOS]:16 TC[Scopus]:16  IF:3.6/3.5 | Submit date：2023/01/31
1,2,4-trioxanes  Aminoperoxides  Cancer  Malaria  Reactive Oxygen Species  
Antimalarial and antitumour activities of the steroidal quinone-methide celastrol and its combinations with artemiside, artemisone and methylene blue Journal article
Ng, Jerome P.L., Han, Yu, Yang, Li Jun, Birkholtz, Lyn Marie, Coertzen, Dina, Wong, Ho Ning, Haynes, Richard K., Coghi, Paolo, Wong, Vincent Kam Wai. Antimalarial and antitumour activities of the steroidal quinone-methide celastrol and its combinations with artemiside, artemisone and methylene blue[J]. Frontiers in Pharmacology, 2022, 13.
Authors:  Ng, Jerome P.L.;  Han, Yu;  Yang, Li Jun;  Birkholtz, Lyn Marie;  Coertzen, Dina; et al.
Favorite | TC[WOS]:1 TC[Scopus]:1  IF:4.4/5.0 | Submit date：2023/01/30
Artemisinin  Artemisone  Cancer  Celastrol  Malaria  Redox Drug  Synergism  
Design, synthesis and antitumor evaluation of novel 1H-indole-2-carboxylic acid derivatives targeting 14-3-3η protein Journal article
Gao, Zhenxiong, Fan, Tingting, Chen, Linbo, Yang, Mengchu, Wai Wong, Vincent Kam, Chen, Dawei, Liu, Zijian, Zhou, Yaoyao, Wu, Weibin, Qiu, Zixuan, Zhang, Cunlong, Li, Yuan, Jiang, Yuyang. Design, synthesis and antitumor evaluation of novel 1H-indole-2-carboxylic acid derivatives targeting 14-3-3η protein[J]. European Journal of Medicinal Chemistry, 2022, 238.
Authors:  Gao, Zhenxiong;  Fan, Tingting;  Chen, Linbo;  Yang, Mengchu;  Wai Wong, Vincent Kam; et al.
Favorite | TC[WOS]:3 TC[Scopus]:3  IF:6.0/6.1 | Submit date：2023/01/30
14-3-3η Protein  Antitumor Bioactivity  Drug Design  Hepatocellular Carcinoma  Novel Target  
Targeting microglial autophagic degradation of the NLRP3 inflammasome for identification of thonningianin A in Alzheimer’s disease Journal article
Zhou, Xiao Gang, Qiu, Wen Qiao, Yu, Lu, Pan, Rong, Teng, Jin Feng, Sang, Zhi Pei, Law, Betty Yuen Kwan, Zhao, Ya, Zhang, Li, Yan, Lu, Tang, Yong, Sun, Xiao Lei, Wong, Vincent Kam Wai, Yu, Chong Lin, Wu, Jian Ming, Qin, Da Lian, Wu, An Guo. Targeting microglial autophagic degradation of the NLRP3 inflammasome for identification of thonningianin A in Alzheimer’s disease[J]. Inflammation and Regeneration, 2022, 42(1).
Authors:  Zhou, Xiao Gang;  Qiu, Wen Qiao;  Yu, Lu;  Pan, Rong;  Teng, Jin Feng; et al.
Favorite | TC[WOS]:23 TC[Scopus]:23  IF:5.0/7.2 | Submit date：2023/01/30
Alzheimer’s Disease  Ampk/ulk1  Autophagy  Nlrp3 Inflammasome  Raf/mek/erk  Thonningianin a