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Discovery of potent LRRK2 inhibitors by ensemble virtual screening strategy and bioactivity evaluation
Journal article
Gong, Xiaoqing, Li, Shuli, Huang, Junli, Tan, Shuoyan, Zhang, Qianqian, Tian, Yanan, Li, Qin, Wang, Lingling, Tong, Henry H.Y., Yao, Xiaojun, Chen, Chunxia, Lee, Simon Ming Yuen, Liu, Huanxiang. Discovery of potent LRRK2 inhibitors by ensemble virtual screening strategy and bioactivity evaluation[J]. European Journal of Medicinal Chemistry, 2024, 279, 116812.
Authors:
Gong, Xiaoqing
;
Li, Shuli
;
Huang, Junli
;
Tan, Shuoyan
;
Zhang, Qianqian
; et al.
Favorite
|
TC[WOS]:
0
TC[Scopus]:
0
IF:
6.0
/
6.1
|
Submit date:2024/10/10
Fingerprint
Lrrk2
Molecular Docking
Pharmacophore
Virtual Screening
Zebrafish
Prevalence of subthreshold depression and its related factors in Chinese college students: A cross-sectional study
Journal article
Ge, Pu, Tan, Cheng, Liu, Jia xin, Cai, Qiong, Zhao, Si qi, Hong, Wen ying, Liu, Kun meng, Qi, Jia le, Hu, Chen, Yu, Wen li, Li, Yi miao, You, Yuan, Guo, Jin han, Hao, Ming yan, Chen, Yang, Pan, Lu tong, Liu, Di yue, Yan, Meng yao, Zhang, Jin zi, Li, Qi yu, Sun, Bo ya, Han, Xiao, Mo, Fuer, Wu, Yi bo, Bian, Ying. Prevalence of subthreshold depression and its related factors in Chinese college students: A cross-sectional study[J]. Heliyon, 2024, 10(12), e32595.
Authors:
Ge, Pu
;
Tan, Cheng
;
Liu, Jia xin
;
Cai, Qiong
;
Zhao, Si qi
; et al.
Favorite
|
TC[WOS]:
0
TC[Scopus]:
1
IF:
3.4
/
3.9
|
Submit date:2024/07/04
China
College Students
Cross-sectional Investigation
Mental Health
Phq-9
Subthreshold Depression
Iristectorigenin C suppresses LPS-induced macrophages activation by regulating mPGES-1 expression and p38/JNK pathway
Journal article
Guo, Xin, Yao, Yun Da, Kang, Jun Li, Luo, Fu Kang, Mu, Xi Jun, Zhang, Yan Yu, Chen, Ming Tai, Liu, Meng Nan, Lao, Chi Chou, Tan, Zi Hao, Huang, Yu Feng, Xie, Ying, Xu, You Hua, Wu, Peng, Zhou, Hua. Iristectorigenin C suppresses LPS-induced macrophages activation by regulating mPGES-1 expression and p38/JNK pathway[J]. Journal of Ethnopharmacology, 2023, 317, 116706.
Authors:
Guo, Xin
;
Yao, Yun Da
;
Kang, Jun Li
;
Luo, Fu Kang
;
Mu, Xi Jun
; et al.
Favorite
|
TC[WOS]:
1
TC[Scopus]:
1
IF:
4.8
/
4.8
|
Submit date:2023/09/21
Inflammation
Iris Tectorum
Iristectorigenin c
Mapk Pathway
Mpges-1
Chemical mitophagy modulators: Drug development strategies and novel regulatory mechanisms
Journal article
Dong,Yu, Zhuang,Xu Xu, Wang,Yi Ting, Tan,Jieqiong, Feng,Du, Li,Min, Zhong,Qing, Song,Zhiyin, Shen,Han Ming, Fang,Evandro F., Lu,Jia Hong. Chemical mitophagy modulators: Drug development strategies and novel regulatory mechanisms[J]. Pharmacological Research, 2023, 194, 106835.
Authors:
Dong,Yu
;
Zhuang,Xu Xu
;
Wang,Yi Ting
;
Tan,Jieqiong
;
Feng,Du
; et al.
Favorite
|
TC[WOS]:
12
TC[Scopus]:
11
IF:
9.1
/
9.0
|
Submit date:2023/08/03
Cancer
Cardiovascular Diseases
Drug Development
Metabolic Disorders
Mitophagy
Neurodegenerative Diseases
Corynoxine B targets at HMGB1/2 to enhance autophagy for α-synuclein clearance in fly and rodent models of Parkinson's disease
Journal article
Qi Zhu, Juxian Song, Jia-Yue Chen, Zhenwei Yuan, Liangfeng Liu, Li-Ming Xie, Qiwen Liao, Richard D. Ye, Xiu Chen, Yepiao Yan, Jieqiong Tan, Chris Soon Heng Tan, Min Li, Jia-Hong Lu. Corynoxine B targets at HMGB1/2 to enhance autophagy for α-synuclein clearance in fly and rodent models of Parkinson's disease[J]. Acta Pharmaceutica Sinica B, 2023, 13(6), 2701-2714.
Authors:
Qi Zhu
;
Juxian Song
;
Jia-Yue Chen
;
Zhenwei Yuan
;
Liangfeng Liu
; et al.
Favorite
|
TC[WOS]:
7
TC[Scopus]:
7
IF:
14.7
/
14.1
|
Submit date:2023/07/20
Autophagy
Corynoxine b
Hmgb1
Hmgb2
Neurodegenerative Disease
Parkinson's Disease
Pi3kc3
Α-synuclein
Moist-Electric Generator with Efficient Output and Scalable Integration Based on Carbonized Polymer Dot and Liquid Metal Active Electrode
Journal article
Li, Qijun, Qin, Yukun, Cheng, Dengke, Cheng, Ming, Zhao, Hongjia, Li, Lvzhou, Qu, Songnan, Tan, Jing, Ding, Jianning. Moist-Electric Generator with Efficient Output and Scalable Integration Based on Carbonized Polymer Dot and Liquid Metal Active Electrode[J]. Advanced Functional Materials, 2023, 33(15), 2211013.
Authors:
Li, Qijun
;
Qin, Yukun
;
Cheng, Dengke
;
Cheng, Ming
;
Zhao, Hongjia
; et al.
Favorite
|
TC[WOS]:
24
TC[Scopus]:
32
IF:
18.5
/
19.6
|
Submit date:2023/05/02
Carbonized Polymer Dots
Flexibility
Liquid Metals
Moisture-electricity Generators
Scalable Integrations
Garbage Classification Detection Model Based on YOLOv4 with Lightweight Neural Network Feature Fusion
Conference paper
Xiao-Feng Wang, Jian-Tao Wang, Li-Xiang Xu, Ming Tan, Jing Yang, Yuan-yan Tang. Garbage Classification Detection Model Based on YOLOv4 with Lightweight Neural Network Feature Fusion[C], 2022, 435-447.
Authors:
Xiao-Feng Wang
;
Jian-Tao Wang
;
Li-Xiang Xu
;
Ming Tan
;
Jing Yang
; et al.
Favorite
|
TC[WOS]:
0
TC[Scopus]:
1
|
Submit date:2023/01/30
Yolov4-lff
Lightweight Neural Networks
Garbage Classification Detection
Feature Fusion
Deep Learning
Evaluation of Preoperative Microvascular Invasion in Hepatocellular Carcinoma Through Multidimensional Parameter Combination Modeling Based on Gd-EOB-DTPA MRI
Journal article
Zhang, Han Dan, Li, Xiao Ming, Zhang, Yu Han, Hu, Fang, Tan, Liang, Wang, Fang, Jing, Yang, Guo, Da Jing, Xu, Yang, Hu, Xian Ling, Liu, Chen, Wang, Jian. Evaluation of Preoperative Microvascular Invasion in Hepatocellular Carcinoma Through Multidimensional Parameter Combination Modeling Based on Gd-EOB-DTPA MRI[J]. Journal of Clinical and Translational Hepatology, 2022, 11(2), 350-359.
Authors:
Zhang, Han Dan
;
Li, Xiao Ming
;
Zhang, Yu Han
;
Hu, Fang
;
Tan, Liang
; et al.
Favorite
|
TC[WOS]:
5
TC[Scopus]:
5
IF:
3.1
/
3.7
|
Submit date:2023/02/28
Hepatocellular Carcinoma
Microvascular Invasion
Radiomics
Gd-eob-dtpa
Enhancing autophagy maturation with CCZ1-MON1A complex alleviates neuropathology and memory defects in Alzheimer disease models
Journal article
Cai, Cui Zan, Zhuang, Xu Xu, Zhu, Qi, Wu, Ming Yue, Su, Huanxing, Wang, Xiao Jin, Iyaswamy, Ashok, Yue, Zhenyu, Wang, Qian, Zhang, Bin, Xue, Yu, Tan, Jieqiong, Li, Min, He, Huanhuan, Lu, Jia Hong. Enhancing autophagy maturation with CCZ1-MON1A complex alleviates neuropathology and memory defects in Alzheimer disease models[J]. Theranostics, 2022, 12(4), 1738-1755.
Authors:
Cai, Cui Zan
;
Zhuang, Xu Xu
;
Zhu, Qi
;
Wu, Ming Yue
;
Su, Huanxing
; et al.
Favorite
|
TC[WOS]:
17
TC[Scopus]:
15
IF:
12.4
/
12.0
|
Submit date:2022/05/17
Alzheimer's Disease
Aβ
Autophagy
Ccz1-mon1a
Rab7
DUSP16 promotes cancer chemoresistance through regulation of mitochondria-mediated cell death
Journal article
Low, Heng Boon, Wong, Zhen Lim, Wu, Bangyuan, Kong, Li Ren, Png, Chin Wen, Cho, Yik Lam, Li, Chun Wei, Xiao, Fengchun, Xin, Xuan, Yang, Henry, Loo, Jia Min, Lee, Fiona Yi Xin, Tan, Iain Bee Huat, DasGupta, Ramanuj, Shen, Han Ming, Schwarz, Herbert, Gascoigne, Nicholas R.J., Goh, Boon Cher, Xu, Xiaohong, Zhang, Yongliang. DUSP16 promotes cancer chemoresistance through regulation of mitochondria-mediated cell death[J]. Nature Communications, 2021, 12(1), 2284.
Authors:
Low, Heng Boon
;
Wong, Zhen Lim
;
Wu, Bangyuan
;
Kong, Li Ren
;
Png, Chin Wen
; et al.
Favorite
|
TC[WOS]:
37
TC[Scopus]:
37
IF:
14.7
/
16.1
|
Submit date:2021/11/30