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Novel Dichloroacetophenone-Based PDHK1 Inhibitors as Potent Anticancer Agents Journal article
Wu, Puhua, Zhang, Zhicheng, Zhou, Yan, Liu, Quan, Tam, Kin Yip, Su, Zhenhong. Novel Dichloroacetophenone-Based PDHK1 Inhibitors as Potent Anticancer Agents[J]. DRUG DESIGN DEVELOPMENT AND THERAPY, 2024, 18, 4661-4679.
Authors:  Wu, Puhua;  Zhang, Zhicheng;  Zhou, Yan;  Liu, Quan;  Tam, Kin Yip; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:4.7/4.8 | Submit date：2024/11/05
Pdhk1  Dichloroacetophenone  Allosteric Pocket  Anti-nsclc Activity  Tumor Xenograft Mouse Model  
Expansion of FGFR3-positive nucleus pulposus cells plays important roles in postnatal nucleus pulposus growth and regeneration Journal article
Xu, Meng, Huang, Junlan, Jin, Min, Jiang, Wanling, Luo, Fengtao, Tan, Qiaoyan, Zhang, Ruobin, Luo, Xiaoqing, Kuang, Liang, Zhang, Dali, Liang, Sen, Qi, Huabing, Chen, Hangang, Ni, Zhenhong, Su, Nan, Yang, Jing, Du, Xiaolan, Chen, Bo, Deng, Chuxia, Xie, Yangli, Chen, Lin. Expansion of FGFR3-positive nucleus pulposus cells plays important roles in postnatal nucleus pulposus growth and regeneration[J]. Stem Cell Research & Therapy, 2022, 13, 227.
Authors:  Xu, Meng;  Huang, Junlan;  Jin, Min;  Jiang, Wanling;  Luo, Fengtao; et al.
Favorite | TC[WOS]:3 TC[Scopus]:4  IF:7.1/7.9 | Submit date：2022/08/02
Intervertebral Disc Degeneration  Nucleus Pulposus  Cell Proliferation  Fgfr3  Genetic Mouse Models  
FGFR3 deficiency enhances CXCL12-dependent chemotaxis of macrophages via upregulating CXCR7 and aggravates joint destruction in mice Journal article
Kuang,Liang, Wu,Jiangyi, Su,Nan, Qi,Huabing, Chen,Hangang, Zhou,Siru, Xiong,Yan, Du,Xiaolan, Tan,Qiaoyan, Yang,Jing, Jin,Min, Luo,Fengtao, Ouyang,Junjie, Zhang,Bin, Wang,Zuqiang, Jiang,Wanling, Chen,Liang, Chen,Shuai, Wang,Ziming, Liu,Peng, Yin,Liangjun, Guo,Fengjin, Deng,Chuxia, Chen,Di, Liu,Chuanju, Xie,Yangli, Ni,Zhenhong, Chen,Lin. FGFR3 deficiency enhances CXCL12-dependent chemotaxis of macrophages via upregulating CXCR7 and aggravates joint destruction in mice[J]. ANNALS OF THE RHEUMATIC DISEASES, 2020, 79(1), 112-122.
Authors:  Kuang,Liang;  Wu,Jiangyi;  Su,Nan;  Qi,Huabing;  Chen,Hangang; et al.
Favorite | TC[WOS]:46 TC[Scopus]:49  IF:20.3/18.4 | Submit date：2020/09/16
Arthritis  Chemokines  Inflammation  Synovitis  
Rmrp Mutation Disrupts Chondrogenesis and Bone Ossification in Zebrafish Model of Cartilage-Hair Hypoplasia via Enhanced Wnt/β-Catenin Signaling Journal article
Sun,Xianding, Zhang,Ruobin, Liu,Mi, Chen,Hangang, Chen,Liang, Luo,Fengtao, Zhang,Dali, Huang,Junlan, Li,Fangfang, Ni,Zhenhong, Qi,Huabing, Su,Nan, Jin,Min, Yang,Jing, Tan,Qiaoyan, Du,Xiaolan, Chen,Bo, Huang,Haiyang, Chen,Shuai, Yin,Liangjun, Xu,Xiaoling, Deng,Chuxia, Luo,Lingfei, Xie,Yangli, Chen,Lin. Rmrp Mutation Disrupts Chondrogenesis and Bone Ossification in Zebrafish Model of Cartilage-Hair Hypoplasia via Enhanced Wnt/β-Catenin Signaling[J]. Journal of Bone and Mineral Research, 2019, 34(11), 2101-2116.
Authors:  Sun,Xianding;  Zhang,Ruobin;  Liu,Mi;  Chen,Hangang;  Chen,Liang; et al.
Favorite | TC[WOS]:16 TC[Scopus]:19  IF:5.1/5.8 | Submit date：2020/09/16
Cartilage-hair Hypoplasia  Rmrp  Skeletal Development  Wnt/β-catenin  Zebrafish  Beta-catenin  
Adeno-Associated Virus-Mediated RNAi against Mutant Alleles Attenuates Abnormal Calvarial Phenotypes in an Apert Syndrome Mouse Model Journal article
Luo,Fengtao, Xie,Yangli, Wang,Zuqiang, Huang,Junlan, Tan,Qiaoyan, Sun,Xianding, Li,Fangfang, Li,Can, Liu,Mi, Zhang,Dali, Xu,Meng, Su,Nan, Ni,Zhenhong, Jiang,Wanling, Chang,Jinhong, Chen,Hangang, Chen,Shuai, Xu,Xiaoling, Deng,Chuxia, Wang,Zhugang, Du,Xiaolan, Chen,Lin. Adeno-Associated Virus-Mediated RNAi against Mutant Alleles Attenuates Abnormal Calvarial Phenotypes in an Apert Syndrome Mouse Model[J]. Molecular Therapy - Nucleic Acids, 2018, 13, 291-302.
Authors:  Luo,Fengtao;  Xie,Yangli;  Wang,Zuqiang;  Huang,Junlan;  Tan,Qiaoyan; et al.
Favorite | TC[WOS]:15 TC[Scopus]:15  IF:6.5/6.7 | Submit date：2020/09/16
Adeno-associated Virus  Apert Syndrome  Craniosynostosis  Fgfr2  Molecular Therapy  Rnai  
A novel FGFR1-binding peptide exhibits anti-tumor effect on lung cancer by inhibiting proliferation and angiogenesis Journal article
Tan,Qiaoyan, Wang,Zuqiang, Wang,Quan, Wang,Yuanqiang, Huang,Zhifeng, Su,Nan, Jin,Min, Kuang,Liang, Qi,Huabing, Ni,Zhenhong, Li,Can, Zhu,Ying, Jiang,Wanling, Chen,Hangang, Deng,Chuxia, Du,Xiao Lan, Xie,Yang Li, Chen,Lin. A novel FGFR1-binding peptide exhibits anti-tumor effect on lung cancer by inhibiting proliferation and angiogenesis[J]. International Journal of Biological Sciences, 2018, 14(10), 1389-1398.
Authors:  Tan,Qiaoyan;  Wang,Zuqiang;  Wang,Quan;  Wang,Yuanqiang;  Huang,Zhifeng; et al.
Favorite | TC[WOS]:14 TC[Scopus]:16  IF:8.2/8.3 | Submit date：2020/09/16
Cancer Therapy  Fgfr1  Lung Cancer  Peptide  Phage Display  
Postnatal deletion of Alk5 gene in meniscal cartilage accelerates age-dependent meniscal degeneration in mice Journal article
Wang,Quan, Tan,Qiaoyan, Xu,Wei, Kuang,Liang, Zhang,Bin, Wang,Zuqiang, Ni,Zhenhong, Su,Nan, Jin,Min, Li,Can, Jiang,Wanling, Huang,Junlan, Li,Fangfang, Zhu,Ying, Chen,Hangang, Du,Xiaolan, Chen,Di, Deng,Chuxia, Qi,Huabing, Xie,Yangli, Chen,Lin. Postnatal deletion of Alk5 gene in meniscal cartilage accelerates age-dependent meniscal degeneration in mice[J]. Journal of Cellular Physiology, 2018, 234(1), 595-605.
Authors:  Wang,Quan;  Tan,Qiaoyan;  Xu,Wei;  Kuang,Liang;  Zhang,Bin; et al.
Favorite | TC[WOS]:6 TC[Scopus]:5  IF:4.5/5.3 | Submit date：2020/09/16
Activing Receptor-like Kinases 5 (Alk5)  Matrix Degradation  Meniscal Degeneration  Transforming Growth Factor-β (Tgf-β) Signaling  
A novel FGFR1-binding peptide exhibits anti-tumor effect on lung cancer by inhibiting proliferation and angiogenesis Journal article
Tan, Qiaoyan, Wang, Zuqiang, Wang, Quan, Wang, Yuanqiang, Huang, Zhifeng, Su, Nan, Jin, Min, Kuang, Liang, Qi, Huabing, Ni, Zhenhong, Li, Can, Zhu, Ying, Jiang, Wanling, Chen, Hangang, Deng, Chuxia, Du, Xiaolan, Xie, Yangli, Chen, Lin. A novel FGFR1-binding peptide exhibits anti-tumor effect on lung cancer by inhibiting proliferation and angiogenesis[J]. INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2018, 14(10), 1389-1398.
Authors:  Tan, Qiaoyan;  Wang, Zuqiang;  Wang, Quan;  Wang, Yuanqiang;  Huang, Zhifeng; et al.
Favorite | TC[WOS]:14 TC[Scopus]:16  IF:8.2/8.3 | Submit date：2018/10/30
Phage Display  Fgfr1  Peptide  Cancer Therapy  Lung Cancer