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Evidence that Mediator is essential for Pol II transcription but is not a required component of the preinitiation complex in vivo Journal article
Petrenko, N, Jin, Y, Wong, K. H., Struhl, K.. Evidence that Mediator is essential for Pol II transcription but is not a required component of the preinitiation complex in vivo[J]. elife, 2017, 1-20.
Authors:  Petrenko, N;  Jin, Y;  Wong, K. H.;  Struhl, K.
Favorite | TC[WOS]:36 TC[Scopus]:31  IF:6.4/7.2 | Submit date:2022/07/27
Mediator  Transcription  
Mediator Undergoes a Compositional Change during Transcriptional Activation Journal article
Petrenko N., Jin Y., Wong K.H., Struhl K.. Mediator Undergoes a Compositional Change during Transcriptional Activation[J]. Molecular Cell, 2016, 64(3), 443.
Authors:  Petrenko N.;  Jin Y.;  Wong K.H.;  Struhl K.
Favorite | TC[WOS]:88 TC[Scopus]:87 | Submit date:2018/10/30
Enhancer  Gene Regulation  Mediator  Promoter  Rna Polymerase Ii  Rna Polymerase Ii C-terminal Domain  Tfiih Kinase  Transcription  Transcriptional Co-activator  
Genome-wide characterization of transcription regulation in fungi Conference paper
Wong, K. H., Tan, K., Hynes, M, Struhl, K. Genome-wide characterization of transcription regulation in fungi[C], 2014.
Authors:  Wong, K. H.;  Tan, K.;  Hynes, M;  Struhl, K
Favorite |  | Submit date:2022/07/27
Genomics  Transcription regulation  Fungi  
TFIIH Phosphorylation of the Pol II CTD Stimulates Mediator Dissociation from the Preinitiation Complex and Promoter Escape Journal article
Wong K.H., Jin Y., Struhl K.. TFIIH Phosphorylation of the Pol II CTD Stimulates Mediator Dissociation from the Preinitiation Complex and Promoter Escape[J]. Molecular Cell, 2014, 54(4), 601.
Authors:  Wong K.H.;  Jin Y.;  Struhl K.
Favorite | TC[WOS]:145 TC[Scopus]:146 | Submit date:2018/10/30
The Cyc8-Tup1 complex inhibits transcription primarily by masking the activation domain of the recruiting protein Journal article
Wong K.H., Struhl K.. The Cyc8-Tup1 complex inhibits transcription primarily by masking the activation domain of the recruiting protein[J]. Genes and Development, 2011, 25(23), 2525-2539.
Authors:  Wong K.H.;  Struhl K.
Favorite | TC[WOS]:102 TC[Scopus]:107 | Submit date:2019/01/16
Cyc8-tup1  Gene Regulation  Stress Responses Transcriptional Activation  Transcriptional Corepressor  Transcriptional Repression  
Extensive divergence of yeast stress responses through transitions between induced and constitutive activation Journal article
Tirosh I., Wong K.H., Barkai N., Struhl K.. Extensive divergence of yeast stress responses through transitions between induced and constitutive activation[J]. Proceedings of the National Academy of Sciences of the United States of America, 2011, 108(40), 16693-16698.
Authors:  Tirosh I.;  Wong K.H.;  Barkai N.;  Struhl K.
Favorite | TC[WOS]:27 TC[Scopus]:31 | Submit date:2019/01/16
Biological Function  Evolutionary Conservation  Functional Evolution  Gene Regulation  
The Cyc8−Tup1 complex inhibits transcription primarily by masking the activation domain of the recruiting protein. Journal article
Wong, K. H., Struhl, K. . The Cyc8−Tup1 complex inhibits transcription primarily by masking the activation domain of the recruiting protein.[J]. Genes and Development, 2011, 2525-2539.
Authors:  Wong, K. H.;  Struhl, K.
Favorite |   IF:7.5/10.5 | Submit date:2022/08/19
Cyc8−Tup1 complex  transcription  activation domain  recruiting protein