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Corynoxine B targets at HMGB1/2 to enhance autophagy for α-synuclein clearance in fly and rodent models of Parkinson's disease Journal article
Qi Zhu, Juxian Song, Jia-Yue Chen, Zhenwei Yuan, Liangfeng Liu, Li-Ming Xie, Qiwen Liao, Richard D. Ye, Xiu Chen, Yepiao Yan, Jieqiong Tan, Chris Soon Heng Tan, Min Li, Jia-Hong Lu. Corynoxine B targets at HMGB1/2 to enhance autophagy for α-synuclein clearance in fly and rodent models of Parkinson's disease[J]. Acta Pharmaceutica Sinica B, 2023, 13(6), 2701-2714.
Authors:  Qi Zhu;  Juxian Song;  Jia-Yue Chen;  Zhenwei Yuan;  Liangfeng Liu; et al.
Favorite | TC[WOS]:7 TC[Scopus]:7  IF:14.7/14.1 | Submit date：2023/07/20
Autophagy  Corynoxine b  Hmgb1  Hmgb2  Neurodegenerative Disease  Parkinson's Disease  Pi3kc3  Α-synuclein  
Editorial: Assessing the Pharmacological Effects and Therapeutic Potential of Traditional Chinese Medicine in Neurological Disease Models: An Update Other
2022-04-27
Authors:  Deng, Zhiqiang;  Kan, Yuxuan;  Li, Min;  Song, Juxian;  Lu, Jia Hong
Favorite | TC[WOS]:2 TC[Scopus]:2 | Submit date：2022/08/05
Dementia  Epilepsy  Multiple Sclerosis  Neurodegenerative Diseases  Stroke  
Lysosomal TPCN (two pore segment channel) inhibition ameliorates beta-amyloid pathology and mitigates memory impairment in Alzheimer disease Journal article
Tong, Benjamin Chun Kit, Wu, Aston Jiaxi, Huang, Alexis Shiying, Dong, Rui, Malampati, Sandeep, Iyaswamy, Ashok, Krishnamoorthi, Senthilkumar, Sreenivasmurthy, Sravan Gopalkrishnashetty, Zhu, Zhou, Su, Chengfu, Liu, Jia, Song, Juxian, Lu, Jia Hong, Tan, Jieqiong, Pan, Weidong, Li, Min, Cheung, King Ho. Lysosomal TPCN (two pore segment channel) inhibition ameliorates beta-amyloid pathology and mitigates memory impairment in Alzheimer disease[J]. Autophagy, 2021, 18(3), 624-642.
Authors:  Tong, Benjamin Chun Kit;  Wu, Aston Jiaxi;  Huang, Alexis Shiying;  Dong, Rui;  Malampati, Sandeep; et al.
Favorite | TC[WOS]:30 TC[Scopus]:30  IF:14.6/16.8 | Submit date：2022/05/17
Alzheimer Disease  Autophagy-lysosomal Pathway  Calcium Ion  Presenilin-1  Two Pore Segment Channel 2  
Corynoxine Protects Dopaminergic Neurons Through Inducing Autophagy and Diminishing Neuroinflammation in Rotenone-Induced Animal Models of Parkinson’s Disease Journal article
Chen, Leilei, Huang, Yujv, Yu, Xing, Lu, Jiahong, Jia, Wenting, Song, Juxian, Liu, Liangfeng, Wang, Youcui, Huang, Yingyu, Xie, Junxia, Li, Min. Corynoxine Protects Dopaminergic Neurons Through Inducing Autophagy and Diminishing Neuroinflammation in Rotenone-Induced Animal Models of Parkinson’s Disease[J]. FRONTIERS IN PHARMACOLOGY, 2021, 12, 642900.
Authors:  Chen, Leilei;  Huang, Yujv;  Yu, Xing;  Lu, Jiahong;  Jia, Wenting; et al.
Favorite | TC[WOS]:72 TC[Scopus]:76  IF:4.4/5.0 | Submit date：2021/12/07
Autophagy  Corynoxine  Neuroinflammation  Parkinson’s Disease  Rotenone  Α-synuclein  
A curcumin derivative activates TFEB and protects against parkinsonian neurotoxicity in vitro Journal article
Wang,Ziying, Yang,Chuanbin, Liu,Jia, Tong,Benjamin Chun Kit, Zhu,Zhou, Malampati,Sandeep, Sreenivasmurthy,Sravan Gopalkrishnashetty, Cheung,King Ho, Iyaswamy,Ashok, Su,Chengfu, Lu,Jiahong, Song,Juxian, Li,Min. A curcumin derivative activates TFEB and protects against parkinsonian neurotoxicity in vitro[J]. International Journal of Molecular Sciences, 2020, 21(4), 1515.
Authors:  Wang,Ziying;  Yang,Chuanbin;  Liu,Jia;  Tong,Benjamin Chun Kit;  Zhu,Zhou; et al.
Favorite | TC[WOS]:33 TC[Scopus]:40  IF:4.9/5.6 | Submit date：2021/03/02
Curcumin Derivatives  Mtorc1  Parkinson’s Disease  Tfeb  Α-synuclein  
Balancing mTOR signaling and autophagy in the treatment of Parkinson’s disease Journal article
Zhu,Zhou, Yang,Chuanbin, Iyaswamy,Ashok, Krishnamoorthi,Senthilkumar, Sreenivasmurthy,Sravan Gopalkrishnashetty, Liu,Jia, Wang,Ziying, Tong,Benjamin Chun Kit, Song,Juxian, Lu,Jiahong, Cheung,King Ho, Li,Min. Balancing mTOR signaling and autophagy in the treatment of Parkinson’s disease[J]. International Journal of Molecular Sciences, 2019, 20(3), 728.
Authors:  Zhu,Zhou;  Yang,Chuanbin;  Iyaswamy,Ashok;  Krishnamoorthi,Senthilkumar;  Sreenivasmurthy,Sravan Gopalkrishnashetty; et al.
Favorite | TC[WOS]:165 TC[Scopus]:172 | Submit date：2021/03/02
Autophagy  Mtor  Parkinson’s Disease