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The new andrographolide derivative AGS-30 induces apoptosis in human colon cancer cells by activating a ROS-dependent JNK signalling pathway Journal article
Liu, Zhuyun, Wu, Xiaoping, Dai, Kun, Li, Renkai, Zhang, Jinming, Sheng, Dekuan, Lee, Simon Ming Yuen, Leung, George Pak Heng, Zhou, Guo Chun, Li, Jingjing. The new andrographolide derivative AGS-30 induces apoptosis in human colon cancer cells by activating a ROS-dependent JNK signalling pathway[J]. PHYTOMEDICINE, 2022, 94, 153824.
Authors:  Liu, Zhuyun;  Wu, Xiaoping;  Dai, Kun;  Li, Renkai;  Zhang, Jinming; et al.
Favorite | TC[WOS]:14 TC[Scopus]:16  IF:6.7/6.2 | Submit date：2022/02/21
Andrographolide Derivative  Apoptosis  Colon Cancer  Reactive Oxygen Species  
AGS-30, an andrographolide derivative, suppresses tumor angiogenesis and growth in vitro and in vivo Journal article
Li,Jingjing, Li,Feng, Tang,Fan, Zhang,Jinming, Li,Renkai, Sheng,Dekuan, Lee,Simon Ming Yuen, Zhou,Guo Chun, Leung,George Pak Heng. AGS-30, an andrographolide derivative, suppresses tumor angiogenesis and growth in vitro and in vivo[J]. BIOCHEMICAL PHARMACOLOGY, 2020, 171, 113694.
Authors:  Li,Jingjing;  Li,Feng;  Tang,Fan;  Zhang,Jinming;  Li,Renkai; et al.
Favorite | TC[WOS]:25 TC[Scopus]:29  IF:5.3/5.2 | Submit date：2021/03/01
Andrographolide Derivative  Anti-angiogenic  Colon Cancer  Vegf  
Discovery and preliminary SAR of 14-aryloxy-andrographolide derivatives as antibacterial agents with immunosuppressant activity Journal article
Li, Feng, Li, Xiao-Min, Sheng, Dekuan, Chen, Shao-Ru, Nie, Xin, Liu, Zhuyun, Wang, Decai, Zhao, Qi, Wang, Yitao, Wang, Ying, Zhou, Guo-Chun. Discovery and preliminary SAR of 14-aryloxy-andrographolide derivatives as antibacterial agents with immunosuppressant activity[J]. RSC ADVANCES, 2018, 8(17), 9440-9456.
Authors:  Li, Feng;  Li, Xiao-Min;  Sheng, Dekuan;  Chen, Shao-Ru;  Nie, Xin; et al.
View | Adobe PDF | Favorite | TC[WOS]:20 TC[Scopus]:21  IF:3.9/3.9 | Submit date：2018/10/30
Differential: In vitro and in vivo anti-angiogenic activities of acetal and ketal andrographolide derivatives in HUVEC and zebrafish models Journal article
Dekuan Sheng, Jingjing Li, Kun Wang, Yuran Peng, Shang Li, Yicheng Sun, Zhuyun Liu, Decai Wang, Simon Ming Yuen Lee, Guo-Chun Zhou. Differential: In vitro and in vivo anti-angiogenic activities of acetal and ketal andrographolide derivatives in HUVEC and zebrafish models[J]. RSC Advances, 2016, 6(105), 102831-102842.
Authors:  Dekuan Sheng;  Jingjing Li;  Kun Wang;  Yuran Peng;  Shang Li; et al.
Favorite | TC[WOS]:10 TC[Scopus]:14 | Submit date：2018/11/06
SAR studies of 3,14,19-derivatives of andrographolide on anti-proliferative activity to cancer cells and toxicity to zebrafish: An in vitro and in vivo study Journal article
Yuran Peng, Jingjing Li, Yicheng Sun, Judy Yuet-Wa Chan, Dekuan Sheng, Kun Wang, Ping Wei, Pingkai Ouyang, Decai Wang, Simon Ming Yuen Lee, Guo-Chun Zhou. SAR studies of 3,14,19-derivatives of andrographolide on anti-proliferative activity to cancer cells and toxicity to zebrafish: An in vitro and in vivo study[J]. RSC Advances, 2015, 5(29), 22510-22526.
Authors:  Yuran Peng;  Jingjing Li;  Yicheng Sun;  Judy Yuet-Wa Chan;  Dekuan Sheng; et al.
Favorite | TC[WOS]:26 TC[Scopus]:26  IF:3.9/3.9 | Submit date：2018/11/06