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Proteases—From Basic Structure to Function to Drug Design as Targeted Therapy Book
Kwok, Hang Fai, Shaw, Chris, Walker, Brian. Proteases—From Basic Structure to Function to Drug Design as Targeted Therapy[M]. Switzerland:MDPI, 2021.
Authors:  Kwok, Hang Fai;  Shaw, Chris;  Walker, Brian
Favorite | TC[WOS]:1 TC[Scopus]:1 | Submit date：2022/06/02
Protease Inhibitor  Targeted Therapy  Drug Design And Development  Oncology  Precision Medicine  
A novel bioengineered fragment peptide of Vasostatin-1 exerts smooth muscle pharmacological activities and anti-angiogenic effects via blocking VEGFR signalling pathway Journal article
Wei, Ran, Wu, Qiushuang, Ai, Nana, Wang, Lei, Zhou, Mei, Shaw, Chris, Chen, Tianbao, Ye, Richard Dequan, Ge, Wei, Siu, Shirley W.I., Kwok, Hang Fai. A novel bioengineered fragment peptide of Vasostatin-1 exerts smooth muscle pharmacological activities and anti-angiogenic effects via blocking VEGFR signalling pathway[J]. Computational and Structural Biotechnology Journal, 2021, 19, 2664-2675.
Authors:  Wei, Ran;  Wu, Qiushuang;  Ai, Nana;  Wang, Lei;  Zhou, Mei; et al.
Favorite | TC[WOS]:5 TC[Scopus]:5  IF:4.4/5.0 | Submit date：2021/09/17
Anti-angiogenesis  Chromogranin a  Vasostatin-1  Vegfr2  
Enhanced Antimicrobial Activity of N-Terminal Derivatives of a Novel Brevinin-1 Peptide from the Skin Secretion of Odorrana schmackeri Journal article
Zhou,Xiaowei, Liu,Yue, Gao,Yitian, Wang,Yuanxing, Xia,Qiang, Zhong,Ruimin, Ma,Chengbang, Zhou,Mei, Xi,Xinping, Shaw,Chris, Chen,Tianbao, Wu,Di, Kwok,Hang Fai, Wang,Lei. Enhanced Antimicrobial Activity of N-Terminal Derivatives of a Novel Brevinin-1 Peptide from the Skin Secretion of Odorrana schmackeri[J]. Toxins, 2020, 12(8).
Authors:  Zhou,Xiaowei;  Liu,Yue;  Gao,Yitian;  Wang,Yuanxing;  Xia,Qiang; et al.
Favorite | TC[WOS]:24 TC[Scopus]:25  IF:3.9/4.2 | Submit date：2021/03/04
Antimicrobial Activity  Skin-derived Peptides  Stability  Waxworm Model  
Pharmacological effects of a novel bradykinin-related peptide (RR-18) from the skin secretion of the hejiang frog (Ordorrana hejiangensis) on smooth muscle Journal article
Zhou,Xiaowei, Xu,Jie, Zhong,Ruimin, Ma,Chengbang, Zhou,Mei, Cao,Zhijian, Xi,Xinping, Shaw,Chris, Chen,Tianbao, Wang,Lei, Kwok,Hang Fai. Pharmacological effects of a novel bradykinin-related peptide (RR-18) from the skin secretion of the hejiang frog (Ordorrana hejiangensis) on smooth muscle[J]. Biomedicines, 2020, 8(7), 225.
Authors:  Zhou,Xiaowei;  Xu,Jie;  Zhong,Ruimin;  Ma,Chengbang;  Zhou,Mei; et al.
Favorite | TC[WOS]:3 TC[Scopus]:3  IF:3.9/4.1 | Submit date：2021/03/04
Antagonist  Bradykinin Related Peptide  Frog  Skin Secretion  Smooth Muscle  
In Vitro and MD Simulation Study to Explore Physicochemical Parameters for Antibacterial Peptide to Become Potent Anticancer Peptide Journal article
Ma,Rui, Wong,Sin Wa, Ge,Lilin, Shaw,Chris, Siu,Shirley W.I., Kwok,Hang Fai. In Vitro and MD Simulation Study to Explore Physicochemical Parameters for Antibacterial Peptide to Become Potent Anticancer Peptide[J]. Molecular Therapy-Oncolytics, 2020, 16, 7-19.
Authors:  Ma,Rui;  Wong,Sin Wa;  Ge,Lilin;  Shaw,Chris;  Siu,Shirley W.I.; et al.
Favorite | TC[WOS]:47 TC[Scopus]:47  IF:5.3/5.2 | Submit date：2021/03/04
Angiogenesis  Anticancer Peptides  Antimicrobial Peptides  Apoptosis  Drug Discovery And Development  Molecular Dynamics  Targeted Therapy  
LFB: A Novel Antimicrobial Brevinin-Like Peptide from the Skin Secretion of the Fujian Large Headed Frog, Limnonectes fujianensi Journal article
Bin Li, Peng Lyu, Shuping Xie, Haixin Qin, Wenyuan Pu, Houxi Xu, Tianbao Chen, Chris Shaw, Lilin Ge, Hang Fai Kwok. LFB: A Novel Antimicrobial Brevinin-Like Peptide from the Skin Secretion of the Fujian Large Headed Frog, Limnonectes fujianensi[J]. BIOMOLECULES, 2019, 9(6).
Authors:  Bin Li;  Peng Lyu;  Shuping Xie;  Haixin Qin;  Wenyuan Pu; et al.
Favorite | TC[WOS]:20 TC[Scopus]:22  IF:4.8/5.4 | Submit date：2020/05/20
Amphibian  Brevinin-like Peptide  Antimicrobial Peptides  Drug Discovery  
Identification and pharmaceutical evaluation of novel frog skin-derived serine proteinase inhibitor peptide PE-BBI (Pelophylax esculentus Bowman-Birk inhibitor) for the potential treatment of cancer Journal article
Lyu, Peng, Ge, Lilin, Ma, Rui, Wei, Ran, McCrudden, Cian M., Chen, Tianbao, Shaw, Chris, Kwok, Hang Fai. Identification and pharmaceutical evaluation of novel frog skin-derived serine proteinase inhibitor peptide PE-BBI (Pelophylax esculentus Bowman-Birk inhibitor) for the potential treatment of cancer[J]. SCIENTIFIC REPORTS, 2018, 8.
Authors:  Lyu, Peng;  Ge, Lilin;  Ma, Rui;  Wei, Ran;  McCrudden, Cian M.; et al.
Favorite | TC[WOS]:17 TC[Scopus]:18  IF:3.8/4.3 | Submit date：2018/10/30
Triggering of cancer cell cycle arrest by a novel scorpion venom-derived peptide-Gonearrestide Journal article
Li, Bin, Lyu, Peng, Xi, Xinping, Ge, Lilin, Mahadevappa, Ravikiran, Shaw, Chris, Kwok, Hang Fai. Triggering of cancer cell cycle arrest by a novel scorpion venom-derived peptide-Gonearrestide[J]. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2018, 22(9), 4460-4473.
Authors:  Li, Bin;  Lyu, Peng;  Xi, Xinping;  Ge, Lilin;  Mahadevappa, Ravikiran; et al.
Favorite | TC[WOS]:41 TC[Scopus]:42 | Submit date：2018/10/30
Anticancer Mechanism  Binding Sites  Ms  Ms Proteome  Ngs Transcriptome  Signalling Pathways  Venom Library