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Novel tricyclic azepine derivatives: Biological evaluation of pyrimido[4,5-b]-1,4-benzoxazepines, thiazepines, and diazepines as inhibitors of the epidermal growth factor receptor tyrosine kinase Journal article
Smith II L., Wong W.C., Kiselyov A.S., Burdzovic-Wizemann S., Mao Y., Xu Y., Duncton M.A.J., Kim K., Piatnitski E.L., Doody J.F., Wang Y., Rosler R.L., Milligan D., Columbus J., Balagtas C., Lee S.P., Konovalov A., Hadari Y.R.. Novel tricyclic azepine derivatives: Biological evaluation of pyrimido[4,5-b]-1,4-benzoxazepines, thiazepines, and diazepines as inhibitors of the epidermal growth factor receptor tyrosine kinase[J]. Bioorganic and Medicinal Chemistry Letters, 2006, 16(19), 5102-5106.
Authors:  Smith II L.;  Wong W.C.;  Kiselyov A.S.;  Burdzovic-Wizemann S.;  Mao Y.; et al.
Favorite | TC[WOS]:33 TC[Scopus]:38 | Submit date：2019/01/16
Diazepine  Epidermal Growth Factor Receptor  Kinase Inhibitor  Oxazepine  Thiazepine  
Tricyclic azepine derivatives: Pyrimido[4,5-b]-1,4-benzoxazepines as a novel class of epidermal growth factor receptor kinase inhibitors Journal article
Smith II L., Piatnitski E.L., Kiselyov A.S., Ouyang X., Chen X., Burdzovic-Wizemann S., Xu Y., Wang Y., Rosler R.L., Patel S.N., Chiang H.-H., Milligan D.L., Columbus J., Wong W.C., Doody J.F., Hadari Y.R.. Tricyclic azepine derivatives: Pyrimido[4,5-b]-1,4-benzoxazepines as a novel class of epidermal growth factor receptor kinase inhibitors[J]. Bioorganic and Medicinal Chemistry Letters, 2006, 16(6), 1643-1646.
Authors:  Smith II L.;  Piatnitski E.L.;  Kiselyov A.S.;  Ouyang X.;  Chen X.; et al.
Favorite | TC[WOS]:20 TC[Scopus]:19 | Submit date：2019/01/16
Benzoxazepine  Epidermal Growth Factor Receptor  Kinase Inhibitor  Kinase Selectivity  
Oxadiazole derivatives as a novel class of antimitotic agents: Synthesis, inhibition of tubulin polymerization, and activity in tumor cell lines Journal article
Ouyang X., Piatnitski E.L., Pattaropong V., Chen X., He H.-Y., Kiselyov A.S., Velankar A., Kawakami J., Labelle M., Smith II L., Lohman J., Lee S.P., Malikzay A., Fleming J., Gerlak J., Wang Y., Rosler R.L., Zhou K., Mitelman S., Camara M., Surguladze D., Doody J.F., Tuma M.C.. Oxadiazole derivatives as a novel class of antimitotic agents: Synthesis, inhibition of tubulin polymerization, and activity in tumor cell lines[J]. Bioorganic and Medicinal Chemistry Letters, 2006, 16(5), 1191-1196.
Authors:  Ouyang X.;  Piatnitski E.L.;  Pattaropong V.;  Chen X.;  He H.-Y.; et al.
Favorite | TC[WOS]:99 TC[Scopus]:104 | Submit date：2019/01/16
1,3,4-oxadiazole  Antimitotic Agent  Multiple-drug Resistance  Tubulin Polymerization Inhibitor