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Protein Kinase C Modulation Determines the Mesoderm/ Extraembryonic Fate Under BMP4 Induction From Human Pluripotent Stem Cells Journal article
Godoy-Parejo, Carlos, Deng, Chunhao, Xu, Jiaqi, Zhang, Zhaoying, Ren, Zhili, Ai, Nana, Liu, Weiwei, Ge, Wei, Deng, Chuxia, Xu, Xiaoling, Chin, Y. Eugene, Chen, Guokai. Protein Kinase C Modulation Determines the Mesoderm/ Extraembryonic Fate Under BMP4 Induction From Human Pluripotent Stem Cells[J]. Stem Cells, 2023, 41(6), 578-591.
Authors:  Godoy-Parejo, Carlos;  Deng, Chunhao;  Xu, Jiaqi;  Zhang, Zhaoying;  Ren, Zhili; et al.
Favorite | TC[WOS]:2 TC[Scopus]:1  IF:4.0/4.9 | Submit date：2023/07/19
Bmp4  Extraembryonic  Fgf  Gf109203x  Human Embryonic Stem Cells  Mesoderm  Protein Kinase c  Signaling Boundary  Trophoblast  Wnt  
Insulin Directs Dichotomous Translational Regulation to Control Human Pluripotent Stem Cell Survival, Proliferation and Pluripotency Journal article
Zhou, Xiaoxiao, Ren, Zhili, Xu, Jiaqi, Deng, Chunhao, Zhang, Zhaoying, Godoy-Parejo, Carlos, Xu, Faxiang, Huang, Esther Chi Cheng, Wang, Jiajia, Cai, Zheyu, Liu, Weiwei, Hu, Guang, Chen, Guokai. Insulin Directs Dichotomous Translational Regulation to Control Human Pluripotent Stem Cell Survival, Proliferation and Pluripotency[J]. International Journal of Biological Sciences, 2022, 18(9), 3562-3575.
Authors:  Zhou, Xiaoxiao;  Ren, Zhili;  Xu, Jiaqi;  Deng, Chunhao;  Zhang, Zhaoying; et al.
Favorite | TC[WOS]:1 TC[Scopus]:1  IF:8.2/8.3 | Submit date：2022/08/05
Cell Survival  Insulin  Akt  Noxa/pmaip1  Mtor  Eif4e  Pluripotency  Proliferation  Translation  Human Pluripotent Stem Cell (Hpsc)  
Thyroid hormone enhances stem cell maintenance and promotes lineage-specific differentiation in human embryonic stem cells Journal article
Chunhao Deng, Zhaoying Zhang, Faxiang Xu, Jiaqi Xu, Zhili Ren, Carlos Godoy-Parejo, Xia Xiao, Weiwei Liu, Zhou Zhou, Guokai Chen. Thyroid hormone enhances stem cell maintenance and promotes lineage-specific differentiation in human embryonic stem cells[J]. Stem Cell Research and Therapy, 2022, 13(1).
Authors:  Chunhao Deng;  Zhaoying Zhang;  Faxiang Xu;  Jiaqi Xu;  Zhili Ren; et al.
Favorite | TC[WOS]:6 TC[Scopus]:6  IF:7.1/7.9 | Submit date：2022/05/13
Cell Culture  Hpscs  Pluripotency  Thyroid Hormone  Triiodothyronine (T3)  Trophoblast  
Nicotinamide promotes pancreatic differentiation through the dual inhibition of CK1 and ROCK kinases in human embryonic stem cells Journal article
Zhang, Yumeng, Xu, Jiaqi, Ren, Zhili, Meng, Ya, Liu, Weiwei, Lu, Ligong, Zhou, Zhou, Chen, Guokai. Nicotinamide promotes pancreatic differentiation through the dual inhibition of CK1 and ROCK kinases in human embryonic stem cells[J]. Stem Cell Research & Therapy, 2021, 12(1), 362.
Authors:  Zhang, Yumeng;  Xu, Jiaqi;  Ren, Zhili;  Meng, Ya;  Liu, Weiwei; et al.
Favorite | TC[WOS]:12 TC[Scopus]:15  IF:7.1/7.9 | Submit date：2021/12/09
Casein Kinase 1 (Ck1)  Human Embryonic Stem Cells  Kinase Inhibitor  Nicotinamide  Pancreatic Progenitors  Rho-associated Protein Kinase (Rock)  
Lysophosphatidic acid shifts metabolic and transcriptional landscapes to induce a distinct cellular state in human pluripotent stem cells Journal article
Xu, Faxiang, Deng, Chunhao, Ren, Zhili, Sun, Liangyu, Meng, Ya, Liu, Weiwei, Wan, Jianbo, Chen, Guokai. Lysophosphatidic acid shifts metabolic and transcriptional landscapes to induce a distinct cellular state in human pluripotent stem cells[J]. Cell Reports, 2021, 37(9), 110063.
Authors:  Xu, Faxiang;  Deng, Chunhao;  Ren, Zhili;  Sun, Liangyu;  Meng, Ya; et al.
Favorite | TC[WOS]:13 TC[Scopus]:13  IF:7.5/8.5 | Submit date：2021/12/08
Cellular State  Hpsc  Lipid  Lpa  Metabolism  Mitochondria  Pluripotency  Transcriptome  
Nicotinamide promotes cardiomyocyte derivation and survival through kinase inhibition in human pluripotent stem cells Journal article
Meng, Ya, Song, Chengcheng, Ren, Zhili, Li, Xiaohong, Yang, Xiangyu, Ai, Nana, Yang, Yang, Wang, Dongjin, Zhan, Meixiao, Wang, Jiaxian, Lei, Chon Lok, Liu, Weiwei, Ge, Wei, Lu, Ligong, Chen, Guokai. Nicotinamide promotes cardiomyocyte derivation and survival through kinase inhibition in human pluripotent stem cells[J]. Cell Death and Disease, 2021, 12, 1119.
Authors:  Meng, Ya;  Song, Chengcheng;  Ren, Zhili;  Li, Xiaohong;  Yang, Xiangyu; et al.
Favorite | TC[WOS]:4 TC[Scopus]:4  IF:8.1/8.6 | Submit date：2021/12/08
Insulin Promotes Mitochondrial Respiration and Survival through PI3K/AKT/GSK3 Pathway in Human Embryonic Stem Cells Journal article
Ren,Zhili, Zhong,Hui, Song,Chengcheng, Deng,Chunhao, Hsieh,Hsun Ting, Liu,Weiwei, Chen,Guokai. Insulin Promotes Mitochondrial Respiration and Survival through PI3K/AKT/GSK3 Pathway in Human Embryonic Stem Cells[J]. Stem Cell Reports, 2020, 15(6), 1362-1376.
Authors:  Ren,Zhili;  Zhong,Hui;  Song,Chengcheng;  Deng,Chunhao;  Hsieh,Hsun Ting; et al.
Favorite | TC[WOS]:22 TC[Scopus]:25  IF:5.9/5.9 | Submit date：2021/03/02
Akt  Caspase  Cell Survival  Gsk3  Human Embryonic Stem Cells  Insulin  Mitochondrial Respiration  
Novel venom-based peptides (P13 and its derivative - M6) to maintain self-renewal of human embryonic stem cells by activating FGF and TGFβ signaling pathways Journal article
Ma,Rui, Ren,Zhili, Li,Bin, Siu,Shirley W.I., Chen,Guokai, Kwok,Hang Fai. Novel venom-based peptides (P13 and its derivative - M6) to maintain self-renewal of human embryonic stem cells by activating FGF and TGFβ signaling pathways[J]. Stem Cell Research and Therapy, 2020, 11(1), 243.
Authors:  Ma,Rui;  Ren,Zhili;  Li,Bin;  Siu,Shirley W.I.;  Chen,Guokai; et al.
Favorite | TC[WOS]:4 TC[Scopus]:4  IF:7.1/7.9 | Submit date：2021/03/04
Embryonic Stem Cell  Peptide Modification  Pluripotency  Self-renewal  Venom Peptide  
Stagewise keratinocyte differentiation from human embryonic stem cells by defined signal transduction modulators Journal article
Zhong,Hui, Ren,Zhili, Wang,Xiaoyan, Miao,Kai, Ni,Wenjun, Meng,Ya, Lu,Ligong, Wang,Chunming, Liu,Weiwei, Deng,Chu Xia, Xu,Ren He, Chen,Guokai. Stagewise keratinocyte differentiation from human embryonic stem cells by defined signal transduction modulators[J]. International Journal of Biological Sciences, 2020, 16(8), 1450-1462.
Authors:  Zhong,Hui;  Ren,Zhili;  Wang,Xiaoyan;  Miao,Kai;  Ni,Wenjun; et al.
Favorite | TC[WOS]:15 TC[Scopus]:16  IF:8.2/8.3 | Submit date：2020/09/16
Defined Factors  Human Embryonic Stem Cells  Keratinocyte Differentiation  
Endogenous IGF Signaling Directs Heterogeneous Mesoderm Differentiation in Human Embryonic Stem Cells Journal article
Yang,Yang, Ren,Zhili, Xu,Faxiang, Meng,Ya, Zhang,Yumeng, Ai,Nana, Long,Yan, Fok,Hio Ian, Deng,Chunhao, Zhao,Xianyang, Huang,Liancheng, Zhao,Qi, Wang,Jiaxian, Liu,Weiwei, Ge,Wei, Chen,Guokai. Endogenous IGF Signaling Directs Heterogeneous Mesoderm Differentiation in Human Embryonic Stem Cells[J]. Cell Reports, 2019, 29(11), 3374-3384.e5.
Authors:  Yang,Yang;  Ren,Zhili;  Xu,Faxiang;  Meng,Ya;  Zhang,Yumeng; et al.
Favorite | TC[WOS]:17 TC[Scopus]:17  IF:7.5/8.5 | Submit date：2021/03/02