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Substituted 3-(4-(1,3,5-triazin-2-yl)-phenyl)-2-aminopropanoic acids as novel tryptophan hydroxylase inhibitors Journal article
Jin H., Cianchetta G., Devasagayaraj A., Gu K., Marinelli B., Samala L., Scott S., Stouch T., Tunoori A., Wang Y., Zang Y., Zhang C., David Kimball S., Main A.J., Ding Z.-M., Sun W., Yang Q., Yu X.-Q., Powell D.R., Wilson A., Liu Q., Shi Z.-C.. Substituted 3-(4-(1,3,5-triazin-2-yl)-phenyl)-2-aminopropanoic acids as novel tryptophan hydroxylase inhibitors[J]. Bioorganic and Medicinal Chemistry Letters, 2009, 19(17), 5229-5232.
Authors:  Jin H.;  Cianchetta G.;  Devasagayaraj A.;  Gu K.;  Marinelli B.; et al.
Favorite | TC[WOS]:32 TC[Scopus]:31 | Submit date：2019/01/16
5-ht  Gastrointestinal Disorders  Tph1  Tryptophan Hydroxylase  
Modulation of peripheral serotonin levels by novel tryptophan hydroxylase inhibitors for the potential treatment of functional gastrointestinal disorders Journal article
Shi Z.-C., Devasagayaraj A., Gu K., Jin H., Marinelli B., Samala L., Scott S., Stouch T., Tunoori A., Wang Y., Zang Y., Zhang C., Kimball S.D., Main A.J., Sun W., Yang Q., Nouraldeen A., Yu X.-Q., Buxton E., Patel S., Nguyen N., Swaffield J., Powell D.R., Wilson A., Liu Q.. Modulation of peripheral serotonin levels by novel tryptophan hydroxylase inhibitors for the potential treatment of functional gastrointestinal disorders[J]. Journal of Medicinal Chemistry, 2008, 51(13), 3684-3687.
Authors:  Shi Z.-C.;  Devasagayaraj A.;  Gu K.;  Jin H.;  Marinelli B.; et al.
Favorite | TC[WOS]:55 TC[Scopus]:59 | Submit date：2019/01/16
Chronic morphine exposure increases the phosphorylation of MAP kinases and the transcription factor CREB in dorsal root ganglion neurons: An in vitro and in vivo study Journal article
Ma W., Zheng W.-H., Powell K., Jhamandas K., Quirion R.. Chronic morphine exposure increases the phosphorylation of MAP kinases and the transcription factor CREB in dorsal root ganglion neurons: An in vitro and in vivo study[J]. European Journal of Neuroscience, 2001, 14(7), 1091-1104.
Authors:  Ma W.;  Zheng W.-H.;  Powell K.;  Jhamandas K.;  Quirion R.
Favorite | TC[WOS]:134 TC[Scopus]:144 | Submit date：2018/12/21
Calcitonin Gene-related Peptide  Cell Culture  Naloxone  Opiates  Substance p  Tolerance