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Simultaneous Targeting of NPC1 and VDAC1 by Itraconazole Leads to Synergistic Inhibition of mTOR Signaling and Angiogenesis Journal article
Head, Sarah A., Shi, Wei Q., Yang, Eun Ju, Nacev, Benjamin A., Hong, Sam Y., Pasunooti, Kalyan K., Li, Ruo-Jing, Shim, Joong Sup, Liu, Jun O.. Simultaneous Targeting of NPC1 and VDAC1 by Itraconazole Leads to Synergistic Inhibition of mTOR Signaling and Angiogenesis[J]. ACS CHEMICAL BIOLOGY, 2017, 12(1), 174-182.
Authors:  Head, Sarah A.;  Shi, Wei Q.;  Yang, Eun Ju;  Nacev, Benjamin A.;  Hong, Sam Y.; et al.
Favorite | TC[WOS]:65 TC[Scopus]:66  IF:3.5/3.9 | Submit date：2018/10/30
Antifungal drug itraconazole targets VDAC1 to modulate the AMPK/mTOR signaling axis in endothelial cells Journal article
Head S.A., Shi W., Zhao L., Gorshkov K., Pasunooti K., Chen Y., Deng Z., Li R.-J., Shim J.S., Tan W., Hartung T., Zhang J., Zhao Y., Colombini M., Liu J.O.. Antifungal drug itraconazole targets VDAC1 to modulate the AMPK/mTOR signaling axis in endothelial cells[J]. Proceedings of the National Academy of Sciences of the United States of America, 2015, 112(52), E7276.
Authors:  Head S.A.;  Shi W.;  Zhao L.;  Gorshkov K.;  Pasunooti K.; et al.
Favorite | TC[WOS]:85 TC[Scopus]:91 | Submit date：2018/10/30
Angiogenesis  Itraconazole  Metabolism  Mitochondria  Vdac1