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TNFR2 antagonistic antibody induces the death of tumor infiltrating CD4+Foxp3+ regulatory T cells Journal article
He, Tianzhen, Chen, Yibo, Yang, De, Islam, Md Sahidul, Chou, Chon Kit, Liu, Jiarui, Faustman, Denise L., Oppenheim, Joost J., Chen, Xin*. TNFR2 antagonistic antibody induces the death of tumor infiltrating CD4+Foxp3+ regulatory T cells[J]. Cellular Oncology, 2022, 46(1), 167-177.
Authors:  He, Tianzhen;  Chen, Yibo;  Yang, De;  Islam, Md Sahidul;  Chou, Chon Kit; et al.
Favorite | TC[WOS]:7 TC[Scopus]:6  IF:4.9/5.2 | Submit date：2023/01/30
cd4+foxp3+ Regulatory t Cells (Tregs)  Cell Death  Lymphoma  Tnfr2  Tnfr2 Antagonistic Antibody  
A TNFR2 antibody by countering immunosuppression cooperates with HMGN1 and R848 immune stimulants to inhibit murine colon cancer Journal article
Jiang, Mengmeng, Liu, Jia, Yang, De, Tross, Debra, Li, Ping, Chen, Fengyang, Alam, Md Masud, Faustman, Denise L., Oppenheim, Joost J., Chen, Xin. A TNFR2 antibody by countering immunosuppression cooperates with HMGN1 and R848 immune stimulants to inhibit murine colon cancer[J]. International Immunopharmacology, 2021, 101, 108345.
Authors:  Jiang, Mengmeng;  Liu, Jia;  Yang, De;  Tross, Debra;  Li, Ping; et al.
Favorite | TC[WOS]:22 TC[Scopus]:22  IF:4.8/5.0 | Submit date：2021/12/08
Antitumor  cd4+foxp3+ Regulatory t Cells (Tregs)  Hmgn1 And R848  Immunotherapy  Tnfr2  
Inhibition of two-pore channels in antigen-presenting cells promotes the expansion of TNFR2-expressing CD4+Foxp3+ regulatory T cells Journal article
He,Tianzhen, Yang,De, Li,Xiao Qing, Jiang,Mengmeng, Islam,Md Sahidul, Chen,Shaokui, Chen,Yibo, Yang,Yang, Chou,Chon Kit, Trivett,Anna L., Oppenheim,Joost J., Chen,Xin*. Inhibition of two-pore channels in antigen-presenting cells promotes the expansion of TNFR2-expressing CD4+Foxp3+ regulatory T cells[J]. Science Advances, 2020, 6(40), eaba6584.
Authors:  He,Tianzhen;  Yang,De;  Li,Xiao Qing;  Jiang,Mengmeng;  Islam,Md Sahidul; et al.
Favorite | TC[WOS]:14 TC[Scopus]:15  IF:11.7/13.7 | Submit date：2021/03/01
Two pore channel inhibitor tetrandrine promotes TNF-TNFR2 interaction resulting in proliferative expansion of CD4+Foxp3+ regulatory T cells Presentation
会议地点: Keystone meeting (Innate Immune Receptors: Roles in Immunology and Beyond), 报告日期: 2019-03-12
Authors:  He, T;  Trivett, A.;  Li, X.;  Yang, D.;  Oppenheim, J.; et al.
Favorite |  | Submit date：2022/08/30
Blockade of TNFR2 signaling enhances the immunotherapeutic effect of CpG ODN in a mouse model of colon cancer Journal article
Nie, Yingjie, He, Jiang, Shirota, Hidekazu, Trivett, Anna L., Yang, De, Klinman, Dennis M., Oppenheim, Joost J., Chen, Xin. Blockade of TNFR2 signaling enhances the immunotherapeutic effect of CpG ODN in a mouse model of colon cancer[J]. SCIENCE SIGNALING, 2018, 11(511).
Authors:  Nie, Yingjie;  He, Jiang;  Shirota, Hidekazu;  Trivett, Anna L.;  Yang, De; et al.
Favorite | TC[WOS]:53 TC[Scopus]:56  IF:6.7/7.2 | Submit date：2018/10/30
Development of a Curative Therapeutic Vaccine (TheraVac) for the Treatment of Big Solid Tumors Journal article
Nie, Y.J., Yang, D., Trivett, A., Xin, H.Y., Han, Zh., Chen, X., Oppenheim, J.. Development of a Curative Therapeutic Vaccine (TheraVac) for the Treatment of Big Solid Tumors[J]. Scientific reports, 2017, 1-12.
Authors:  Nie, Y.J.;  Yang, D.;  Trivett, A.;  Xin, H.Y.;  Han, Zh.; et al.
Favorite |   IF:3.8/4.3 | Submit date：2022/08/30
CT26 tumors  immunotherapeutic  tumor-specific immunity  
Development of a Curative Therapeutic Vaccine (TheraVac) for the Treatment of Large Established Tumors Journal article
Nie, Yingjie, Yang, De, Trivett, Anna, Han, Zhen, Xin, Haiyun, Chen, Xin, Oppenheim, Joost J.. Development of a Curative Therapeutic Vaccine (TheraVac) for the Treatment of Large Established Tumors[J]. SCIENTIFIC REPORTS, 2017, 7.
Authors:  Nie, Yingjie;  Yang, De;  Trivett, Anna;  Han, Zhen;  Xin, Haiyun; et al.
Favorite | TC[WOS]:29 TC[Scopus]:30  IF:3.8/4.3 | Submit date：2018/10/30
The decisive role of TNF-TNFR2 pathway in the activation of CD4+Foxp3+ regulatory T cells: implications in tumor immunotherapy Presentation
会议地点: . Leukocytebiology 2017 (2017 Society of Leukocyte Biology 50th Anniversary Meeting). Vancouver, Canada., 报告日期: 2017-10-06
Authors:  Chen, X.;  Oppenheim, J.
Favorite |  | Submit date：2022/08/30
Targeting TNFR2, an immune checkpoint stimulator and oncoprotein, is a promising treatment for cancer Journal article
Chen, Xin, Oppenheim, Joost J.. Targeting TNFR2, an immune checkpoint stimulator and oncoprotein, is a promising treatment for cancer[J]. SCIENCE SIGNALING, 2017, 10(462).
Authors:  Chen, Xin;  Oppenheim, Joost J.
Favorite | TC[WOS]:60 TC[Scopus]:59  IF:6.7/7.2 | Submit date：2018/10/30
Suppressive activity of human Treg cells is maintained in the presence of TNF Journal article
Zaragoza, B., Chen, X., Oppenheim, J., Baeyens, A., Gregoire, S., Chader, D., Miyara, M., Salomon, B.. Suppressive activity of human Treg cells is maintained in the presence of TNF[J]. Nature Medicine, 2016, 16-17.
Authors:  Zaragoza, B.;  Chen, X.;  Oppenheim, J.;  Baeyens, A.;  Gregoire, S.; et al.
Favorite |   IF:58.7/59.2 | Submit date：2022/08/30
Treg cells  anti-TNF  TNF  TNFR2