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Lysosomal TPCN (two pore segment channel) inhibition ameliorates beta-amyloid pathology and mitigates memory impairment in Alzheimer disease Journal article
Tong, Benjamin Chun Kit, Wu, Aston Jiaxi, Huang, Alexis Shiying, Dong, Rui, Malampati, Sandeep, Iyaswamy, Ashok, Krishnamoorthi, Senthilkumar, Sreenivasmurthy, Sravan Gopalkrishnashetty, Zhu, Zhou, Su, Chengfu, Liu, Jia, Song, Juxian, Lu, Jia Hong, Tan, Jieqiong, Pan, Weidong, Li, Min, Cheung, King Ho. Lysosomal TPCN (two pore segment channel) inhibition ameliorates beta-amyloid pathology and mitigates memory impairment in Alzheimer disease[J]. Autophagy, 2021, 18(3), 624-642.
Authors:  Tong, Benjamin Chun Kit;  Wu, Aston Jiaxi;  Huang, Alexis Shiying;  Dong, Rui;  Malampati, Sandeep; et al.
Favorite | TC[WOS]:30 TC[Scopus]:30  IF:14.6/16.8 | Submit date：2022/05/17
Alzheimer Disease  Autophagy-lysosomal Pathway  Calcium Ion  Presenilin-1  Two Pore Segment Channel 2  
A curcumin derivative activates TFEB and protects against parkinsonian neurotoxicity in vitro Journal article
Wang,Ziying, Yang,Chuanbin, Liu,Jia, Tong,Benjamin Chun Kit, Zhu,Zhou, Malampati,Sandeep, Sreenivasmurthy,Sravan Gopalkrishnashetty, Cheung,King Ho, Iyaswamy,Ashok, Su,Chengfu, Lu,Jiahong, Song,Juxian, Li,Min. A curcumin derivative activates TFEB and protects against parkinsonian neurotoxicity in vitro[J]. International Journal of Molecular Sciences, 2020, 21(4), 1515.
Authors:  Wang,Ziying;  Yang,Chuanbin;  Liu,Jia;  Tong,Benjamin Chun Kit;  Zhu,Zhou; et al.
Favorite | TC[WOS]:33 TC[Scopus]:40  IF:4.9/5.6 | Submit date：2021/03/02
Curcumin Derivatives  Mtorc1  Parkinson’s Disease  Tfeb  Α-synuclein  
A small molecule transcription factor EB activator ameliorates beta-amyloid precursor protein and Tau pathology in Alzheimer's disease models Journal article
Ju-Xian Song, Sandeep Malampati, Yu Zeng, Siva Sundara Kumar Durairajan, Chuan-Bin Yang, Benjamin Chun-Kit Tong, Ashok Iyaswamy, Wen-Bin Shang, Sreenivasmurthy,Sravan Gopalkrishnashetty, Zhou Zhu, King-Ho Cheung, Jia-Hong Lu, Chunzhi Tang, Nenggui Xu, Min Li. A small molecule transcription factor EB activator ameliorates beta-amyloid precursor protein and Tau pathology in Alzheimer's disease models[J]. AGING CELL, 2020, 19(2).
Authors:  Ju-Xian Song;  Sandeep Malampati;  Yu Zeng;  Siva Sundara Kumar Durairajan;  Chuan-Bin Yang; et al.
Favorite | TC[WOS]:106 TC[Scopus]:113  IF:8.0/9.7 | Submit date：2021/03/02
Alzheimer's Disease  Beta-amyloid  Curcumin Analog C1  Mapt/tau  Tfeb  
Targeting Aggrephagy for the Treatment of Alzheimer's Disease Journal article
Malampati, Sandeep, Song, Ju Xian, Chun-Kit Tong, Benjamin, Nalluri, Anusha, Yang, Chuan Bin, Wang, Ziying, Gopalkrishnashetty Sreenivasmurthy, Sravan, Zhu, Zhou, Liu, Jia, Su, Chengfu, Krishnamoorthi, Senthilkumar, Iyaswamy, Ashok, Cheung, King Ho, Lu, Jia Hong, Li, Min. Targeting Aggrephagy for the Treatment of Alzheimer's Disease[J]. Cells, 2020, 9(2), 311.
Authors:  Malampati, Sandeep;  Song, Ju Xian;  Chun-Kit Tong, Benjamin;  Nalluri, Anusha;  Yang, Chuan Bin; et al.
Favorite | TC[WOS]:38 TC[Scopus]:38  IF:5.1/6.0 | Submit date：2021/12/03
Aggregates  Aggrephagy  Alzheimer’s Disease  Selective Autophagy