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Tanshinone IIA attenuates insulin like growth factor 1-induced cell proliferation in PC12 cells through the PI3K/Akt and MEK/ERK pathways Journal article
Wang H., Su X., Fang J., Xin X., Zhao X., Gaur U., Wen Q., Xu J., Little P.J., Zheng W.. Tanshinone IIA attenuates insulin like growth factor 1-induced cell proliferation in PC12 cells through the PI3K/Akt and MEK/ERK pathways[J]. International Journal of Molecular Sciences, 2018, 19(9).
Authors:  Wang H.;  Su X.;  Fang J.;  Xin X.;  Zhao X.; et al.
Favorite | TC[WOS]:18 TC[Scopus]:21 | Submit date：2018/12/21
Akt  Antiproliferation  Erk  Igf-1r  Tanshinone Iia  
Flavopiridol inhibits TGF-b-stimulated biglycan synthesis by blocking linker region phosphorylation and nuclear translocation of Smad2 Journal article
Rostam M.A., Shajimoon A., Kamato D., Mitra P., Piva T.J., Getachew R., Cao Y., Zheng W., Osman N., Little P.J.. Flavopiridol inhibits TGF-b-stimulated biglycan synthesis by blocking linker region phosphorylation and nuclear translocation of Smad2[J]. Journal of Pharmacology and Experimental Therapeutics, 2018, 365(1), 156-164.
Authors:  Rostam M.A.;  Shajimoon A.;  Kamato D.;  Mitra P.;  Piva T.J.; et al.
Favorite | TC[WOS]:25 TC[Scopus]:24 | Submit date：2018/12/21
Role of brain-derived neurotrophic factor and nerve growth factor in the regulation of Neuropeptide W in vitro and in vivo Journal article
Wang R., Yan F., Liao R., Wan P., Little P.J., Zheng W.. Role of brain-derived neurotrophic factor and nerve growth factor in the regulation of Neuropeptide W in vitro and in vivo[J]. Molecular and Cellular Endocrinology, 2017, 447, 71-78.
Authors:  Wang R.;  Yan F.;  Liao R.;  Wan P.;  Little P.J.; et al.
Favorite | TC[WOS]:12 TC[Scopus]:11 | Submit date：2018/12/21
Hpa Axis  Neuropeptide w  Neurotrophins  Pi3k/akt  
Elucidating the role of the FoxO3a transcription factor in the IGF-1-induced migration and invasion of uveal melanoma cancer cells Journal article
Yan F., Liao R., Farhan M., Wang T., Chen J., Wang Z., Little P.J., Zheng W.. Elucidating the role of the FoxO3a transcription factor in the IGF-1-induced migration and invasion of uveal melanoma cancer cells[J]. Biomedicine and Pharmacotherapy, 2016, 84, 1538-1550.
Authors:  Yan F.;  Liao R.;  Farhan M.;  Wang T.;  Chen J.; et al.
Favorite | TC[WOS]:30 TC[Scopus]:31 | Submit date：2018/12/21
Foxo3a Translocation  Igf-1  Metastases  Uveal Melanoma  
Multiple growth factors, but not VEGF, stimulate glycosaminoglycan hyperelongation in retinal choroidal endothelial cells Journal article
Al Gwairi O., Osman N., Getachew R., Zheng W., Liang X.-L., Kamato D., Thach L., Little P.J.. Multiple growth factors, but not VEGF, stimulate glycosaminoglycan hyperelongation in retinal choroidal endothelial cells[J]. International Journal of Biological Sciences, 2016, 12(9), 1041-1051.
Authors:  Al Gwairi O.;  Osman N.;  Getachew R.;  Zheng W.;  Liang X.-L.; et al.
Favorite | TC[WOS]:4 TC[Scopus]:4 | Submit date：2018/12/21
Age Related Macular Degeneration  Bruch's Membrane  Growth Factors  Proteoglycans  Vegf  Xyloside  
Evaluation of the potential synergism of imatinib-related poly kinase inhibitors using growth factor stimulated proteoglycan synthesis as a model response Journal article
Bernard R., Getachew R., Kamato D., Thach L., Osman N., Chan V., Zheng W., Little P.J.. Evaluation of the potential synergism of imatinib-related poly kinase inhibitors using growth factor stimulated proteoglycan synthesis as a model response[J]. Journal of Pharmacy and Pharmacology, 2016, 68(3), 368-378.
Authors:  Bernard R.;  Getachew R.;  Kamato D.;  Thach L.;  Osman N.; et al.
Favorite | TC[WOS]:8 TC[Scopus]:8 | Submit date：2018/12/21
Cell Signalling  Gag Hyperelongation  Platelet Derived Growth Factor  Proteoglycan  Tinibs  Transforming Growth Factor-β  
The role of specific Smad linker region phosphorylation in TGF-β mediated expression of glycosaminoglycan synthesizing enzymes in vascular smooth muscle Journal article
Rostam M.A., Kamato D., Piva T.J., Zheng W., Little P.J., Osman N.. The role of specific Smad linker region phosphorylation in TGF-β mediated expression of glycosaminoglycan synthesizing enzymes in vascular smooth muscle[J]. Cellular Signalling, 2016, 28(8), 956.
Authors:  Rostam M.A.;  Kamato D.;  Piva T.J.;  Zheng W.;  Little P.J.; et al.
Favorite | TC[WOS]:42 TC[Scopus]:45 | Submit date：2018/10/30
Atherosclerosis  Glycosaminoglycan  Signalling  Smad  Transforming Growth Factor-β  Vascular Smooth Muscle  
Lithium ions attenuate serum-deprivation-induced apoptosis in PC12 cells through regulation of the Akt/FoxO1 signaling pathways Journal article
Zeng Z., Wang H., Shang F., Zhou L., Little P.J., Quirion R., Zheng W.. Lithium ions attenuate serum-deprivation-induced apoptosis in PC12 cells through regulation of the Akt/FoxO1 signaling pathways[J]. Psychopharmacology, 2016, 233(5), 785.
Authors:  Zeng Z.;  Wang H.;  Shang F.;  Zhou L.;  Little P.J.; et al.
Favorite | TC[WOS]:25 TC[Scopus]:26 | Submit date：2018/10/30
Apoptosis  Lithium  Neuroprotection  Pi3k/akt/foxo1  Serum Deprivation  
Integrating the GPCR transactivation-dependent and biased signalling paradigms in the context of PAR1 signalling Journal article
Little P.J., Hollenberg M.D., Kamato D., Thomas W., Chen J., Wang T., Zheng W., Osman N.. Integrating the GPCR transactivation-dependent and biased signalling paradigms in the context of PAR1 signalling[J]. British Journal of Pharmacology, 2016, 173(20), 2992-3000.
Authors:  Little P.J.;  Hollenberg M.D.;  Kamato D.;  Thomas W.;  Chen J.; et al.
Favorite | TC[WOS]:7 TC[Scopus]:11 | Submit date：2018/12/21
Protease activated receptor-1 mediated dual kinase receptor transactivation stimulates the expression of glycosaminoglycan synthesizing genes Journal article
Kamato D., Thach L., Getachew R., Burch M., Hollenberg M.D., Zheng W., Little P.J., Osman N.. Protease activated receptor-1 mediated dual kinase receptor transactivation stimulates the expression of glycosaminoglycan synthesizing genes[J]. Cellular Signalling, 2016, 28(1), 110-119.
Authors:  Kamato D.;  Thach L.;  Getachew R.;  Burch M.;  Hollenberg M.D.; et al.
Favorite | TC[WOS]:36 TC[Scopus]:36 | Submit date：2018/12/21
Glycosaminoglycan Enzymes  Smad Linker Region  Thrombin  Transactivation-dependent  Transforming Growth Factor β