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Targeting the phosphatidylglycerol lipid: An amphiphilic dendrimer as a promising antibacterial candidate Journal article
Zhang, Nian, Dhumal, Dinesh, Kuo, Shanny Hsuan, Lew, Shi Qian, Patil, Pankaj D., Taher, Raleb, Vaidya, Sanika, Galanakou, Christina, Elkihel, Abdechakour, Oh, Myung Whan, Chong, Sook Yin, Marson, Domenico, Zheng, Jun, Rouvinski, Oleg, Abolarin, Williams O., Pricl, Sabrina, Lau, Gee W., Lee, Leo Tsz On, Peng, Ling. Targeting the phosphatidylglycerol lipid: An amphiphilic dendrimer as a promising antibacterial candidate[J]. Science Advances, 2024, 10(39), eadn8117.
Authors:  Zhang, Nian;  Dhumal, Dinesh;  Kuo, Shanny Hsuan;  Lew, Shi Qian;  Patil, Pankaj D.; et al.
Favorite | TC[WOS]:1 TC[Scopus]:0  IF:11.7/13.7 | Submit date:2024/10/10
RNA therapeutics in targeting G protein-coupled receptors: Recent advances and challenges Review article
2024
Authors:  Yuan, Wanjun;  Shi, Xiangyang;  Lee, Leo Tsz On
Favorite | TC[WOS]:1 TC[Scopus]:1  IF:6.5/6.7 | Submit date:2024/05/16
Drug Delivery  g Protein-coupled Receptor  Mt: Oligonucleotides: Therapies And Applications  Nanoparticles  Rna Therapeutics  
Amphiphilic Dendrimer as Potent Antibacterial against Drug-Resistant Bacteria in Mouse Models of Human Infectious Diseases Journal article
King, Noah, Dhumal, Dinesh, Lew, Shi Qian, Kuo, Shanny Hsuan, Galanakou, Christina, Oh, Myung Whan, Chong, Sook Yin, Zhang, Nian, Lee, Leo Tsz On, Hayouka, Zvi, Peng, Ling, Lau, Gee W.. Amphiphilic Dendrimer as Potent Antibacterial against Drug-Resistant Bacteria in Mouse Models of Human Infectious Diseases[J]. ACS Infectious Diseases, 2024, 10(2), 453-466.
Authors:  King, Noah;  Dhumal, Dinesh;  Lew, Shi Qian;  Kuo, Shanny Hsuan;  Galanakou, Christina; et al.
Favorite | TC[WOS]:2 TC[Scopus]:2  IF:4.0/4.3 | Submit date:2024/03/07
Amphiphilic Dendrimer  In Vivo Efficacy  Klebsiella Pneumoniae  Pseudomonas Aeruginosa  Staphylococcus Aureus  
The application of dendrimer-small RNA system to target renin-angiotensin system for cancer therapy Presentation
会议地点: Donghua University, Shanghai, 会议日期: 29-31 Oct, 2023, 报告日期: 2023-10-01
Authors:  LEE TSZ ON
Favorite |  | Submit date:2024/08/21
Repurposing the Hedgehog pathway inhibitor, BMS-833923, as a phosphatidylglycerol-selective membrane-disruptive colistin adjuvant against ESKAPE pathogens Journal article
Zhang,Nian, Shan,Wenying, Gao,Liangliang, Kou,Si Hoi, Lu,Chang, Yang,Huilin, Peng,Bo, Tam,Kin Yip, Lee,Leo Tsz On, Zheng,Jun. Repurposing the Hedgehog pathway inhibitor, BMS-833923, as a phosphatidylglycerol-selective membrane-disruptive colistin adjuvant against ESKAPE pathogens[J]. International Journal of Antimicrobial Agents, 2023, 62(3), 106888.
Authors:  Zhang,Nian;  Shan,Wenying;  Gao,Liangliang;  Kou,Si Hoi;  Lu,Chang; et al.
Favorite | TC[WOS]:4 TC[Scopus]:4  IF:4.9/5.6 | Submit date:2023/08/03
Antibiotic Resistance  Colistin Adjuvant  Drug Repurposing  Eskape  Membrane-disruptive Drug  
ACSL1-induced ferroptosis and platinum resistance in ovarian cancer by increasing FSP1 N-myristylation and stability Journal article
Qingyu Zhang, Ning Li, Limei Deng, Xingmei Jiang, Yuming Zhang, Leo Tsz On Lee, Haitao Zhang. ACSL1-induced ferroptosis and platinum resistance in ovarian cancer by increasing FSP1 N-myristylation and stability[J]. Cell Death Discovery, 2023, 9(1), 83.
Authors:  Qingyu Zhang;  Ning Li;  Limei Deng;  Xingmei Jiang;  Yuming Zhang; et al.
Favorite | TC[WOS]:29 TC[Scopus]:32  IF:6.1/6.0 | Submit date:2023/08/03
Fluorescence intensity and lifetime imaging of lipofuscin-like autofluorescence for label-free predicting clinical drug response in cancer Journal article
Yan, Yinghan, Xing, Fuqiang, Cao, Jiayue, Hu, Yiling, Li, Ling, Cao, Zhengyin, Jia, Hao, Miao, Kai, Shao, Fangyuan, Deng, Chu-Xia, Luo, Kathy Qian, Lee, Leo Tsz on, Liu, Tzu-Ming. Fluorescence intensity and lifetime imaging of lipofuscin-like autofluorescence for label-free predicting clinical drug response in cancer[J]. Redox Biology, 2023, 59(102578), 1-12.
Authors:  Yan, Yinghan;  Xing, Fuqiang;  Cao, Jiayue;  Hu, Yiling;  Li, Ling; et al.
Adobe PDF | Favorite | TC[WOS]:7 TC[Scopus]:10  IF:10.7/11.7 | Submit date:2022/12/27
Apoptosis  Autofluorescence  Label-free  Lipofuscin  Necrosis  
Amphiphilic Dendrimer Doping Enhanced pH-Sensitivity of Liposomal Vesicle for Effective Co-delivery toward Synergistic Ferroptosis–Apoptosis Therapy of Hepatocellular Carcinoma Journal article
Yanhong Su, Zhao Zhang, Leo Tsz On Lee, Ling Peng, Ligong Lu, Xu He, Xuanjun Zhang. Amphiphilic Dendrimer Doping Enhanced pH-Sensitivity of Liposomal Vesicle for Effective Co-delivery toward Synergistic Ferroptosis–Apoptosis Therapy of Hepatocellular Carcinoma[J]. Advanced Healthcare Materials, 2023, 12(6).
Authors:  Yanhong Su;  Zhao Zhang;  Leo Tsz On Lee;  Ling Peng;  Ligong Lu; et al.
Favorite | TC[WOS]:25 TC[Scopus]:25  IF:10.0/11.3 | Submit date:2023/08/03
Advanced Hepatocellular Carcinoma  Amphiphilic Dendrimers  Ferroptosis  Liposomal Vesicles  Synergistic Therapy  
Angiotensin II biased ligand and G protein-coupled kinase 2 mediate beta-arrestin signaling to suppress ovarian cancer cell adhesion Project
项目类型: MYRG, 项目编号: MYRG2022-00240-FHS, 资助机构: UM, 2023-2024
Authors:  LEE TSZ ON
Favorite |  | Submit date:2023/03/29
Src homology 3 domain binding kinase 1 protects against hepatic steatosis and insulin resistance through the Nur77–FGF21 pathway Journal article
Ahuja, Palak, Bi, Xinyi, Ng, Chun Fai, Tse, Margaret Chui Ling, Hang, Miaojia, Pang, Brian Pak Shing, Iu, Elsie Chit Yu, Chan, Wing Suen, Ooi, Xin Ci, Sun, Anqi, Herlea-Pana, Oana, Liu, Zhixue, Yang, Xiuying, Jiao, Baowei, Ma, Xin, Wu, Kelvin Ka Lok, Lee, Leo Tsz On, Cheng, Kenneth King Yip, Lee, Chi Wai, Chan, Chi Bun. Src homology 3 domain binding kinase 1 protects against hepatic steatosis and insulin resistance through the Nur77–FGF21 pathway[J]. Hepatology, 2023, 77(1), 213-229.
Authors:  Ahuja, Palak;  Bi, Xinyi;  Ng, Chun Fai;  Tse, Margaret Chui Ling;  Hang, Miaojia; et al.
Favorite | TC[WOS]:11 TC[Scopus]:11  IF:12.9/15.5 | Submit date:2022/05/17
Growth-factor 21  Orphan Nuclear Receptors  Transcriptional Regulators  Metabolic-activity  Beta-klotho  Expression  Fgf21  Phosphorylation  Activation  Obesity