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CETSA and thermal proteome profiling strategies for target identification and drug discovery of natural products Journal article
Tu,Yanbei, Tan,Lihua, Tao,Hongxun, Li,Yanfang, Liu,Hanqing. CETSA and thermal proteome profiling strategies for target identification and drug discovery of natural products[J]. Phytomedicine, 2023, 116, 154862.
Authors:  Tu,Yanbei;  Tan,Lihua;  Tao,Hongxun;  Li,Yanfang;  Liu,Hanqing
Favorite | TC[WOS]:30 TC[Scopus]:31  IF:6.7/6.2 | Submit date：2023/08/03
Cellular Thermal Shift Assay  Natural Products  Target Discovery  Target Validation  Thermal Proteome Profiling  
Glytabastan B, a coumestan isolated from Glycine tabacina, alleviated synovial inflammation, osteoclastogenesis and collagen-induced arthritis through inhibiting MAPK and PI3K/AKT pathways Journal article
Tu, Yanbei, Tan, Lihua, Lu, Tao, Wang, Kai, Wang, Haiyong, Han, Bing, Zhao, Yuxin, Chen, Hanbin, Li, Yanfang, Chen, Haixia, Chen, Meiwan, He, Chengwei. Glytabastan B, a coumestan isolated from Glycine tabacina, alleviated synovial inflammation, osteoclastogenesis and collagen-induced arthritis through inhibiting MAPK and PI3K/AKT pathways[J]. Biochemical Pharmacology, 2022, 197, 114912.
Authors:  Tu, Yanbei;  Tan, Lihua;  Lu, Tao;  Wang, Kai;  Wang, Haiyong; et al.
Favorite | TC[WOS]:12 TC[Scopus]:15  IF:5.3/5.2 | Submit date：2022/03/28
Glycine Tabacina  Glytabastan b  Inflammation  Network Pharmacology  Osteoclast  Rheumatoid Arthritis  
Serum levels of miR-21-5p and miR-339-5p associate with occupational trichloroethylene hypersensitivity syndrome Journal article
Liu, Wei, Zheng, Jian, Ren, Xiaohu, Xie, Yuxuan, Lin, Dafeng, Li, Peimao, Lv, Yuan, Hoi, Maggie Pui Man, Zhang, Yanfang, Liu, Jianjun. Serum levels of miR-21-5p and miR-339-5p associate with occupational trichloroethylene hypersensitivity syndrome[J]. Journal of Occupational Medicine and Toxicology, 2021, 16(1).
Authors:  Liu, Wei;  Zheng, Jian;  Ren, Xiaohu;  Xie, Yuxuan;  Lin, Dafeng; et al.
Favorite | TC[WOS]:5 TC[Scopus]:6  IF:2.9/2.6 | Submit date：2021/12/09
Biomarkers  Diagnostic Model  Mirnas  Trichloroethylene  Trichloroethylene Hypersensitivity Syndrome  
Investigation of the interaction between Chrysoeriol and xanthine oxidase using computational and in vitro approaches Journal article
Liu, Yan, Han, Chenggang, Lu, Tao, Liu, Yi, Chen, Hao, Yang, Can, Tu, Yanbei, Li, Yanfang. Investigation of the interaction between Chrysoeriol and xanthine oxidase using computational and in vitro approaches[J]. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2021, 190, 463-473.
Authors:  Liu, Yan;  Han, Chenggang;  Lu, Tao;  Liu, Yi;  Chen, Hao; et al.
Favorite | TC[WOS]:27 TC[Scopus]:28  IF:7.7/7.7 | Submit date：2021/12/08
Chrysoeriol  Isothermal Titration Calorimetry  Molecular Simulations  Spectroscopy  Xanthine Oxidase  
Naturally occurring coumestans from plants, their biological activities and therapeutic effects on human diseases Journal article
Tu, Yanbei, Yang, Ying, Li, Yanfang, He, Chengwei. Naturally occurring coumestans from plants, their biological activities and therapeutic effects on human diseases[J]. Pharmacological Research, 2021, 169, 105615.
Authors:  Tu, Yanbei;  Yang, Ying;  Li, Yanfang;  He, Chengwei
Favorite | TC[WOS]:32 TC[Scopus]:35  IF:9.1/9.0 | Submit date：2021/12/08
Bone Diseases  Coumestan  Mechanisms  Natural Products  Organ Damages  Pharmacological Activity  
Isolation and identification of antiarthritic constituents from glycine tabacina and network pharmacology-based prediction of their protective mechanisms against rheumatoid arthritis Journal article
Tu,Yanbei, Wang,Kai, Jia,Xuejing, Tan,Lihua, Han,Bing, Zhang,Qingwen, Li,Yanfang, He,Chengwei. Isolation and identification of antiarthritic constituents from glycine tabacina and network pharmacology-based prediction of their protective mechanisms against rheumatoid arthritis[J]. Journal of Agricultural and Food Chemistry, 2020, 68(39), 10664-10677.
Authors:  Tu,Yanbei;  Wang,Kai;  Jia,Xuejing;  Tan,Lihua;  Han,Bing; et al.
Favorite | TC[WOS]:11 TC[Scopus]:11  IF:5.7/6.0 | Submit date：2021/03/01
Coumestan  Glycine Tabacina  Inflammation  Network Pharmacology  Osteoclastogenesis  Rheumatoid Arthritis  
Oxyberberine, a novel gut microbiota-mediated metabolite of berberine, possesses superior anti-colitis effect: Impact on intestinal epithelial barrier, gut microbiota profile and TLR4-MyD88-NF-κB pathway Journal article
Cailan Li, Gaoxiang Ai, Yongfu Wang, Qiang Lu, Chaodan Luo, Lihua Tan, Guosheng Lin, Yuhong Liu, Yucui Li, Huifang Zeng, Jiannan Chen, Zhixiu Lin, Yanfang Xian, Xiaoqi Huang, Jianhui Xie, Ziren Su. Oxyberberine, a novel gut microbiota-mediated metabolite of berberine, possesses superior anti-colitis effect: Impact on intestinal epithelial barrier, gut microbiota profile and TLR4-MyD88-NF-κB pathway[J]. PHARMACOLOGICAL RESEARCH, 2020, 152.
Authors:  Cailan Li;  Gaoxiang Ai;  Yongfu Wang;  Qiang Lu;  Chaodan Luo; et al.
Favorite | TC[WOS]:178 TC[Scopus]:195  IF:9.1/9.0 | Submit date：2021/12/06
Gut Microflora  Intestinal Epithelial Barrier  Metabolite  Oxyberberine  Tlr4-myd88-nf-κb  Ulcerative Colitis