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Protective effects of Amauroderma rugosum on dextran sulfate sodium-induced ulcerative colitis through the regulation of macrophage polarization and suppression of oxidative stress Journal article
Li, Jingjing, Luo, Xi, Shiu, Polly Ho Ting, Cheng, Yanfen, Nie, Xin, Rangsinth, Panthakarn, Lau, Benson Wui Man, Zheng, Chengwen, Li, Xuebo, Li, Renkai, Lee, Simon Ming Yuen, Fu, Chaomei, Seto, Sai Wang, Zhang, Jinming, Leung, George Pak Heng. Protective effects of Amauroderma rugosum on dextran sulfate sodium-induced ulcerative colitis through the regulation of macrophage polarization and suppression of oxidative stress[J]. Biomedicine and Pharmacotherapy, 2024, 176, 116901.
Authors:  Li, Jingjing;  Luo, Xi;  Shiu, Polly Ho Ting;  Cheng, Yanfen;  Nie, Xin; et al.
Favorite | TC[WOS]:0 TC[Scopus]:1  IF:6.9/6.8 | Submit date：2024/07/04
Amauroderma Rugosum  Macrophage Polarization  Oxidative Stress  Ulcerative Colitis  
Characterization of a polysaccharide from Amauroderma rugosum and its proangiogenic activities in vitro and in vivo Journal article
Nie, Xin, Li, Jingjing, Cheng, Yanfen, Rangsinth, Panthakarn, Wu, Xiaoping, Zheng, Chengwen, Shiu, Polly Ho Ting, Li, Renkai, Xu, Nan, He, Yulin, Lau, Benson Wui Man, Seto, Sai Wang, Zhang, Jinming, Lee, Simon Ming Yuen, Leung, George Pak Heng. Characterization of a polysaccharide from Amauroderma rugosum and its proangiogenic activities in vitro and in vivo[J]. International Journal of Biological Macromolecules, 2024, 271, 132533.
Authors:  Nie, Xin;  Li, Jingjing;  Cheng, Yanfen;  Rangsinth, Panthakarn;  Wu, Xiaoping; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:7.7/7.7 | Submit date：2024/06/05
Amauroderma Rugosum  Polysaccharides  Proangiogenesis  
Structure and activity relationship analysis of xanthones from mangosteen: Identifying garcinone E as a potent dual EGFR and VEGFR2 inhibitor Journal article
Li, Jingjing, Nie, Xin, Panthakarn Rangsinth,, Wu, Xiaoping, Zheng, Chengwen, Cheng, Yanfen, Shiu, Polly Ho Ting, Li, Renkai, Lee, Simon Ming Yuen, Fu, Chaomei, Zhang, Jinming, Leung, George Pak Heng. Structure and activity relationship analysis of xanthones from mangosteen: Identifying garcinone E as a potent dual EGFR and VEGFR2 inhibitor[J]. Phytomedicine, 2024, 122, 155140.
Authors:  Li, Jingjing;  Nie, Xin;  Panthakarn Rangsinth,;  Wu, Xiaoping;  Zheng, Chengwen; et al.
Favorite | TC[WOS]:2 TC[Scopus]:3  IF:6.7/6.2 | Submit date：2024/02/22
Epidermal Growth Factor Receptor  Garcinone e  Mangosteen  Vascular Endothelial Growth Factor Receptor 2  Xanthones  
Glycyrrhetinic acid suppresses breast cancer metastasis by inhibiting M2-like macrophage polarization via activating JNK1/2 signaling Journal article
Yanfen Cheng, Xuemei Zhong, Xin Nie, Huan Gu, Xiaoping Wu, Renkai Li, Yihan Wu, Kongpeng Lv, George Pak-Heng Leung, Chaomei Fu, Simon Ming-Yuen Lee, Jinming Zhang, Jingjing Li. Glycyrrhetinic acid suppresses breast cancer metastasis by inhibiting M2-like macrophage polarization via activating JNK1/2 signaling[J]. Phytomedicine, 2023, 114, 154757.
Authors:  Yanfen Cheng;  Xuemei Zhong;  Xin Nie;  Huan Gu;  Xiaoping Wu; et al.
Favorite | TC[WOS]:20 TC[Scopus]:19  IF:6.7/6.2 | Submit date：2023/07/27
Angiogenesis  Breast Cancer Metastasis  Glycyrrhetinic Acid  Jnk1/2 Pathway  Tumor-associated Macrophages  
Garcinone E suppresses breast cancer growth and metastasis by modulating tumor-associated macrophages polarization via STAT6 signaling Journal article
Nie,Xin, Fu,Li, Cheng,Yanfen, Wu,Xiaoping, Lv,Kongpeng, Li,Renkai, Wu,Yihan, Leung,George Pak Heng, Fu,Chaomei, Lee,Simon Ming Yuen, Seto,Sai Wang, Zhang,Jinming, Li,Jingjing. Garcinone E suppresses breast cancer growth and metastasis by modulating tumor-associated macrophages polarization via STAT6 signaling[J]. Phytotherapy Research, 2023, 37(10), 4442-4456.
Authors:  Nie,Xin;  Fu,Li;  Cheng,Yanfen;  Wu,Xiaoping;  Lv,Kongpeng; et al.
Favorite | TC[WOS]:7 TC[Scopus]:7  IF:6.1/7.0 | Submit date：2023/08/03
Breast Cancer Metastasis  Garcinone e  Stat6 Signaling  Tumor-associated Macrophages  
An Update on the Potential Application of Herbal Medicine in Promoting Angiogenesis Review article
2022
Authors:  Jingjing Li;  Renkai Li;  Xiaoping Wu;  Chengwen Zheng;  Polly Ho-Ting Shiu; et al.
Favorite | TC[WOS]:13 TC[Scopus]:12  IF:4.4/5.0 | Submit date：2022/08/24
Herbal Medicine  Ischemic Diseases  Phytochemicals  Pro-angiogenic  Wound Healing  
Protective Effects of Amauroderma rugosum on Doxorubicin-Induced Cardiotoxicity through Suppressing Oxidative Stress, Mitochondrial Dysfunction, Apoptosis, and Activating Akt/mTOR and Nrf2/HO-1 Signaling Pathways Journal article
Li, Jingjing, Cheng, Yanfen, Li, Renkai, Wu, Xiaoping, Zheng, Chengwen, Shiu, Polly Ho Ting, Chan, Jacqueline Cho Ki, Rangsinth, Panthakarn, Liu, Conghui, Leung, Susan Wai Sum, Lee, Simon Ming Yuen, Zhang, Chen, Fu, Chaomei, Zhang, Jinming, Cheung, Timothy Man Yau, Leung, George Pak Heng. Protective Effects of Amauroderma rugosum on Doxorubicin-Induced Cardiotoxicity through Suppressing Oxidative Stress, Mitochondrial Dysfunction, Apoptosis, and Activating Akt/mTOR and Nrf2/HO-1 Signaling Pathways[J]. Oxidative Medicine and Cellular Longevity, 2022, 2022.
Authors:  Li, Jingjing;  Cheng, Yanfen;  Li, Renkai;  Wu, Xiaoping;  Zheng, Chengwen; et al.
Favorite | TC[WOS]:15 TC[Scopus]:16  IF:7.310/8.427 | Submit date：2022/08/05
Structure-Activity Relationship Studies of 4-((4-(2-fluorophenyl)piperazin-1-yl)methyl)-6-imino-N-(naphthalen-2-yl)-1,3,5-triazin-2-amine (FPMINT) Analogues as Inhibitors of Human Equilibrative Nucleoside Transporters Journal article
Li, Renkai, Mak, Winston Wing Shum, Li, Jingjing, Zheng, Chengwen, Shiu, Polly Ho Ting, Seto, Sai Wang, Lee, Simon Ming Yuen, Leung, George Pak Heng. Structure-Activity Relationship Studies of 4-((4-(2-fluorophenyl)piperazin-1-yl)methyl)-6-imino-N-(naphthalen-2-yl)-1,3,5-triazin-2-amine (FPMINT) Analogues as Inhibitors of Human Equilibrative Nucleoside Transporters[J]. Frontiers in Pharmacology, 2022, 13, 837555.
Authors:  Li, Renkai;  Mak, Winston Wing Shum;  Li, Jingjing;  Zheng, Chengwen;  Shiu, Polly Ho Ting; et al.
Favorite | TC[WOS]:3 TC[Scopus]:3  IF:4.4/5.0 | Submit date：2022/05/17
Equilibrative Nucleoside Transporter  Fpmint  Inhibitor  Mechanism Of Action  Structure-activity Relationship  
The new andrographolide derivative AGS-30 induces apoptosis in human colon cancer cells by activating a ROS-dependent JNK signalling pathway Journal article
Liu, Zhuyun, Wu, Xiaoping, Dai, Kun, Li, Renkai, Zhang, Jinming, Sheng, Dekuan, Lee, Simon Ming Yuen, Leung, George Pak Heng, Zhou, Guo Chun, Li, Jingjing. The new andrographolide derivative AGS-30 induces apoptosis in human colon cancer cells by activating a ROS-dependent JNK signalling pathway[J]. PHYTOMEDICINE, 2022, 94, 153824.
Authors:  Liu, Zhuyun;  Wu, Xiaoping;  Dai, Kun;  Li, Renkai;  Zhang, Jinming; et al.
Favorite | TC[WOS]:14 TC[Scopus]:16  IF:6.7/6.2 | Submit date：2022/02/21
Andrographolide Derivative  Apoptosis  Colon Cancer  Reactive Oxygen Species  
Relaxation effect of narirutin on rat mesenteric arteries via nitric oxide release and activation of voltage-gated potassium channels Journal article
Wong, Emily Sze Wan, Li, Rachel Wai Sum, Li, Jingjing, Li, Renkai, Seto, Sai Wang, Lee, Simon Ming Yuen, Leung, George Pak Heng. Relaxation effect of narirutin on rat mesenteric arteries via nitric oxide release and activation of voltage-gated potassium channels[J]. European Journal of Pharmacology, 2021, 905.
Authors:  Wong, Emily Sze Wan;  Li, Rachel Wai Sum;  Li, Jingjing;  Li, Renkai;  Seto, Sai Wang; et al.
Favorite | TC[WOS]:5 TC[Scopus]:5  IF:4.2/4.3 | Submit date：2021/12/08
Endothelium  Narirutin  Nitric Oxide  Relaxation  Voltage-gated Potassium Channels