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Mitochondrial complex I inhibition by homoharringtonine: A novel strategy for suppression of chronic myeloid leukemia Journal article
Han, Han, Zhao, Chen, Liu, Mengchen, Zhu, Hongxuan, Meng, Fancheng, Zhang, Ying, Wang, Guibin, Wang, Li, Di, Lijun, Mingyuen Lee, Simon, Zhang, Qingwen, Cui, Guozhen. Mitochondrial complex I inhibition by homoharringtonine: A novel strategy for suppression of chronic myeloid leukemia[J]. Biochemical Pharmacology, 2023, 218, 115875.
Authors:  Han, Han;  Zhao, Chen;  Liu, Mengchen;  Zhu, Hongxuan;  Meng, Fancheng; et al.
Favorite | TC[WOS]:3 TC[Scopus]:3  IF:5.3/5.2 | Submit date：2024/01/02
Chronic Myeloid Leukemia  Homoharringtonine  Mitochondrial Complex i  Oxidative Phosphorylation  Proteomics  T315i Mutation  
Therapeutic Effects of Chinese Herbal Formula (PTQX) on NC/Nga Mice with Atopic Dermatitis-Like Skin Lesions Journal article
Yan,Fenggen, Zhang,Jing, Li,Xiong, Mo,Xiumei, Liu,Junfeng, Ye,Siqi, Lin,Ying, Qiu,Xiaohui, Lee,Simon Mingyuen, Chen,Dacan. Therapeutic Effects of Chinese Herbal Formula (PTQX) on NC/Nga Mice with Atopic Dermatitis-Like Skin Lesions[J]. Evidence-based Complementary and Alternative Medicine, 2019, 2019.
Authors:  Yan,Fenggen;  Zhang,Jing;  Li,Xiong;  Mo,Xiumei;  Liu,Junfeng; et al.
Favorite | TC[WOS]:8 TC[Scopus]:7  IF:2.650/3.014 | Submit date：2021/03/01
Cardiotoxicity of forchlorfenuron (CPPU) in zebrafish (Danio rerio) and H9c2 cardiomyocytes Journal article
Guiyi Gong, Hiotong Kam, Yuchung Tse, Simon Mingyuen Lee. Cardiotoxicity of forchlorfenuron (CPPU) in zebrafish (Danio rerio) and H9c2 cardiomyocytes[J]. CHEMOSPHERE, 2019, 235, 153-162.
Authors:  Guiyi Gong;  Hiotong Kam;  Yuchung Tse;  Simon Mingyuen Lee
Favorite | TC[WOS]:39 TC[Scopus]:41  IF:8.1/7.7 | Submit date：2020/01/15
Forchlorfenuron (Cppu)  Zebrafish  Cardiotoxicity  Hematopoietic Toxicity  H9c2 Cardiomyocytes  Cytoskeletons Destruction  
Genome-guided and mass spectrometry investigation of natural products produced by a potential new actinobacterial strain isolated from a mangrove ecosystem in Futian, Shenzhen, China Journal article
Dini Hu, Cheng Gao, Chenghang Sun, Tao Jin, Guangyi Fan, Kai Meng Mok, Simon MingYuen Lee. Genome-guided and mass spectrometry investigation of natural products produced by a potential new actinobacterial strain isolated from a mangrove ecosystem in Futian, Shenzhen, China[J]. Scientific Reports, 2019, 9, 823.
Authors:  Dini Hu;  Cheng Gao;  Chenghang Sun;  Tao Jin;  Guangyi Fan; et al.
Favorite | TC[WOS]:8 TC[Scopus]:9  IF:3.8/4.3 | Submit date：2019/02/12
A novel Ca2+ current blocker promotes angiogenesis and cardiac healing after experimental myocardial infarction in mice Journal article
Guozhen Cui, Qiqi Xin, Hisa Hui Ling Tseng, Maggie PuiMan Hoi, Yan Wang, Binrui Yang, InLeng Choi, Yuqiang Wang, Rong Yuan, Keji Chen, Weihong Cong, Simon MingYuen Lee. A novel Ca2+ current blocker promotes angiogenesis and cardiac healing after experimental myocardial infarction in mice[J]. PHARMACOLOGICAL RESEARCH, 2018, 134, 109-117.
Authors:  Guozhen Cui;  Qiqi Xin;  Hisa Hui Ling Tseng;  Maggie PuiMan Hoi;  Yan Wang; et al.
Favorite | TC[WOS]:16 TC[Scopus]:16  IF:9.1/9.0 | Submit date：2020/01/16
Cardioprotection  Angiogenesis  Adtm  Zebrafish  Vegf  
A Novel Tetramethylpyrazine Derivative Prophylactically Protects against Glutamate-Induced Excitotoxicity in Primary Neurons through the Blockage of N-Methyl-D-aspartate Receptor Journal article
Hu, Shengquan, Hu, Huihui, Mak, Shinghung, Cui, Guozhen, Lee, Mingyuen, Shan, Luchen, Wang, Yuqiang, Lin, Huangquan, Zhang, Zaijun, Han, Yifan. A Novel Tetramethylpyrazine Derivative Prophylactically Protects against Glutamate-Induced Excitotoxicity in Primary Neurons through the Blockage of N-Methyl-D-aspartate Receptor[J]. FRONTIERS IN PHARMACOLOGY, 2018, 9.
Authors:  Hu, Shengquan;  Hu, Huihui;  Mak, Shinghung;  Cui, Guozhen;  Lee, Mingyuen; et al.
Favorite | TC[WOS]:17 TC[Scopus]:19  IF:4.4/5.0 | Submit date：2018/10/30
Alzheimer's Disease  Tetramethylpyrazine Derivative  Nmda Receptor  Neuroprotection  Oxidative Stress  Gsk3 Beta  
pH-sensitive polymeric nanoparticles for co-delivery of doxorubicin and curcumin to treat cancer via enhanced pro-apoptotic and anti-angiogenic activities Journal article
Zhang, Jinming, Li, Jingjing, Shi, Zhi, Yang, Yang, Xie, Xi, Lee, Simon MingYuen, Wang, Yitao, Leong, Kam W., Chen, Meiwan. pH-sensitive polymeric nanoparticles for co-delivery of doxorubicin and curcumin to treat cancer via enhanced pro-apoptotic and anti-angiogenic activities[J]. ACTA BIOMATERIALIA, 2017, 58, 349-364.
Authors:  Zhang, Jinming;  Li, Jingjing;  Shi, Zhi;  Yang, Yang;  Xie, Xi; et al.
Favorite | TC[WOS]:148 TC[Scopus]:163  IF:9.4/9.9 | Submit date：2018/10/30
Anticancer  Ph-sensitive Nanoparticle  Apoptosis  Anti-angiogenesis  Co-delivery  
Indirubin-3-Oxime Prevents H2O2-Induced Neuronal Apoptosis via Concurrently Inhibiting GSK3 beta and the ERK Pathway Journal article
Yu, Jie, Zheng, Jiacheng, Lin, Jiajia, Jin, Linlu, Yu, Rui, Mak, Shinghung, Hu, Shengquan, Sun, Hongya, Wu, Xiang, Zhang, Zaijun, Lee, Mingyuen, Tsim, Wahkeung, Su, Wei, Zhou, Wenhua, Cui, Wei, Han, Yifan, Wang, Qinwen. Indirubin-3-Oxime Prevents H2O2-Induced Neuronal Apoptosis via Concurrently Inhibiting GSK3 beta and the ERK Pathway[J]. CELLULAR AND MOLECULAR NEUROBIOLOGY, 2017, 37(4), 655-664.
Authors:  Yu, Jie;  Zheng, Jiacheng;  Lin, Jiajia;  Jin, Linlu;  Yu, Rui; et al.
Favorite | TC[WOS]:20 TC[Scopus]:23  IF:3.6/4.2 | Submit date：2018/10/30
Indirubin-3-oxime  H2o2  Gsk3 Beta  Pi3-k  Erk  
Indirubin-3-Oxime Prevents H2O2-Induced Neuronal Apoptosis via Concurrently Inhibiting GSK3β and the ERK Pathway Journal article
Yu J., Zheng J., Lin J., Jin L., Yu R., Mak S., Hu S., Sun H., Wu X., Zhang Z., Mingyuen Lee, Tsim W., Su W., Zhou W., Cui W., Han Y., Wang Q.. Indirubin-3-Oxime Prevents H2O2-Induced Neuronal Apoptosis via Concurrently Inhibiting GSK3β and the ERK Pathway[J]. Cellular and Molecular Neurobiology, 2017, 37(4), 655-664.
Authors:  Yu J.;  Zheng J.;  Lin J.;  Jin L.;  Yu R.; et al.
Favorite | TC[WOS]:20 TC[Scopus]:23 | Submit date：2018/11/06
Erk  Gsk3β  H2o2  Indirubin-3-oxime  Pi3-k  
Substantial Neuroprotective and Neurite Outgrowth-Promoting Activities by Bis(propyl)-cognitin via the Activation of Alpha7-nAChR, a Promising Anti-Alzheimer's Dimer Journal article
Shengquan Hu, Wei Cui, Shinghung Mak, Daping Xu, Yuanjia Hu, Jing Tang, Chunglit Choi, Mingyuen Lee, Yuanping Pang, Yifan Han. Substantial Neuroprotective and Neurite Outgrowth-Promoting Activities by Bis(propyl)-cognitin via the Activation of Alpha7-nAChR, a Promising Anti-Alzheimer's Dimer[J]. ACS Chemical Neuroscience, 2015, 6(9), 1536-1545.
Authors:  Shengquan Hu;  Wei Cui;  Shinghung Mak;  Daping Xu;  Yuanjia Hu; et al.
Favorite | TC[WOS]:21 TC[Scopus]:21  IF:4.1/4.3 | Submit date：2018/11/06
Alpha7-nicotinic Acetylcholine Receptor  Alzheimer's Disease  Bis(Propyl)-cognitin  Extracellular Signal-regulated Kinase  Neurite Outgrowth  Neuroprotection