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Habu coagulotoxicity: Clinical implications of the functional diversification of Protobothrops snake venoms upon blood clotting factors Journal article
Debono J., Bos M.H.A., Nouwens A., Ge L., Frank N., Kwok H.F., Fry B.G.. Habu coagulotoxicity: Clinical implications of the functional diversification of Protobothrops snake venoms upon blood clotting factors[J]. Toxicology in Vitro, 2019, 55, 62-74.
Authors:  Debono J.;  Bos M.H.A.;  Nouwens A.;  Ge L.;  Frank N.; et al.
Favorite | TC[WOS]:31 TC[Scopus]:33 | Submit date:2018/12/19
Targeting PD-L1 Protein: Translation, Modification and Transport Journal article
Wei R., Guo L., Wang Q., Miao J., Kwok H.F., Lin Y.. Targeting PD-L1 Protein: Translation, Modification and Transport[J]. Current protein & peptide science, 2019, 20(1), 82-91.
Authors:  Wei R.;  Guo L.;  Wang Q.;  Miao J.;  Kwok H.F.; et al.
Favorite | TC[WOS]:22 TC[Scopus]:22  IF:1.9/3.0 | Submit date:2018/12/19
Immunotherapy  Modification  Programmed Cell Death Protein 1 (Pd-1)  Programmed Death Ligand 1 (Pd-l1)  Translation  Transport.  
DNA replication licensing protein MCM10 promotes tumor progression and is a novel prognostic biomarker and potential therapeutic target in breast cancer Journal article
Mahadevappa R., Neves H., Yuen S.M., Jameel M., Bai Y., Yuen H.-F., Zhang S.-D., Zhu Y., Lin Y., Kwok H.F.. DNA replication licensing protein MCM10 promotes tumor progression and is a novel prognostic biomarker and potential therapeutic target in breast cancer[J]. Cancers, 2018, 10(9).
Authors:  Mahadevappa R.;  Neves H.;  Yuen S.M.;  Jameel M.;  Bai Y.; et al.
Favorite | TC[WOS]:32 TC[Scopus]:32 | Submit date:2018/12/19
Breast Cancer  Knockdown  Mcm10  Overexpression  Proliferation  Survival  
Biological activities of cationicity-enhanced and hydrophobicity-optimized analogues of an antimicrobial peptide, dermaseptin-PS3, from the skin secretion of phyllomedusa sauvagii Journal article
Tan Y., Chen X., Ma C., Xi X., Wang L., Zhou M., Burrows J.F., Kwok H.F., Chen T.. Biological activities of cationicity-enhanced and hydrophobicity-optimized analogues of an antimicrobial peptide, dermaseptin-PS3, from the skin secretion of phyllomedusa sauvagii[J]. Toxins, 2018, 10(8).
Authors:  Tan Y.;  Chen X.;  Ma C.;  Xi X.;  Wang L.; et al.
Favorite | TC[WOS]:20 TC[Scopus]:21 | Submit date:2018/12/19
Anticancer Activity  Antimicrobial Activity  Antimicrobial Peptide (Amp)  Anuran Skin Secretion  Dermaseptin  Drug Design  
Anti-tumor effects of a ‘human & mouse cross-reactive’ anti-ADAM17 antibody in a pancreatic cancer model in vivo Journal article
Ye J., Yuen S.M., Murphy G., Xie R., Kwok H.F.. Anti-tumor effects of a ‘human & mouse cross-reactive’ anti-ADAM17 antibody in a pancreatic cancer model in vivo[J]. European Journal of Pharmaceutical Sciences, 2017, 110, 62-69.
Authors:  Ye J.;  Yuen S.M.;  Murphy G.;  Xie R.;  Kwok H.F.
Favorite | TC[WOS]:22 TC[Scopus]:23  IF:4.3/4.2 | Submit date:2018/12/19
Adam17  Inhibitory Antibody  Pancreatic Ductal Adenocarcinoma (Pdac)  Targeted Therapy  Tumorigenesis  
β-defensin 1 expression in HCV infected liver/liver cancer: An important role in protecting HCV progression and liver cancer development Journal article
Ling Y.-M., Chen J.-Y., Guo L., Wang C.-Y., Tan W.-T., Wen Q., Zhang S.-D., Deng G.-H., Lin Y., Kwok H.F.. β-defensin 1 expression in HCV infected liver/liver cancer: An important role in protecting HCV progression and liver cancer development[J]. Scientific Reports, 2017, 7(1).
Authors:  Ling Y.-M.;  Chen J.-Y.;  Guo L.;  Wang C.-Y.;  Tan W.-T.; et al.
Favorite | TC[WOS]:20 TC[Scopus]:25 | Submit date:2018/12/19
Vascular ADAM17 (a Disintegrin and Metalloproteinase Domain 17) Is Required for Angiotensin II/β-Aminopropionitrile-Induced Abdominal Aortic Aneurysm Journal article
Kawai T., Takayanagi T., Forrester S.J., Preston K.J., Obama T., Tsuji T., Kobayashi T., Boyer M.J., Cooper H.A., Kwok H.F., Hashimoto T., Scalia R., Rizzo V., Eguchi S.. Vascular ADAM17 (a Disintegrin and Metalloproteinase Domain 17) Is Required for Angiotensin II/β-Aminopropionitrile-Induced Abdominal Aortic Aneurysm[J]. Hypertension, 2017, 70(5), 959-963.
Authors:  Kawai T.;  Takayanagi T.;  Forrester S.J.;  Preston K.J.;  Obama T.; et al.
Favorite | TC[WOS]:40 TC[Scopus]:44 | Submit date:2018/12/19
Aneurysm  Angiotensin Ii  Hypertension  Rupture  Signal Transduction  
Coagulating colubrids: Evolutionary, pathophysiological and biodiscovery implications of venom variations between boomslang (Dispholidus typus) and twig snake (Thelotornis mossambicanus) Journal article
Debono J., Dobson J., Casewell N.R., Romilio A., Li B., Kurniawan N., Mardon K., Weisbecker V., Nouwens A., Kwok H.F., Fry B.G.. Coagulating colubrids: Evolutionary, pathophysiological and biodiscovery implications of venom variations between boomslang (Dispholidus typus) and twig snake (Thelotornis mossambicanus)[J]. Toxins, 2017, 9(5).
Authors:  Debono J.;  Dobson J.;  Casewell N.R.;  Romilio A.;  Li B.; et al.
Favorite | TC[WOS]:32 TC[Scopus]:35 | Submit date:2018/12/19
Biodiscovery  Boomslang  Colubridae  Dispholidus Typus  Enzyme Activity  Evolution  Procoagulant  Thelotornis Mossambicanus  
Enter the dragon: The dynamic and multifunctional evolution of anguimorpha lizard venoms Journal article
Koludarov I., Jackson T.N.W., op den Brouw B., Dobson J., Dashevsky D., Arbuckle K., Clemente C.J., Stockdale E.J., Cochran C., Debono J., Stephens C., Panagides N., Li B., Manchadi M.-L.R., Violette A., Fourmy R., Hendrikx I., Nouwens A., Clements J., Martelli P., Kwok H.F., Fry B.G.. Enter the dragon: The dynamic and multifunctional evolution of anguimorpha lizard venoms[J]. Toxins, 2017, 9(8).
Authors:  Koludarov I.;  Jackson T.N.W.;  op den Brouw B.;  Dobson J.;  Dashevsky D.; et al.
Favorite | TC[WOS]:30 TC[Scopus]:38 | Submit date:2018/12/19
Coagulation  Evolution  Fibrinogen  Lizard  Proteomics  Toxicofera  Venom  
CD133 in brain tumor: The prognostic factor Journal article
Li B., McCrudden C.M., Yuen H.F., Xi X., Lyu P., Chan K.W., Zhang S.D., Kwok H.F.. CD133 in brain tumor: The prognostic factor[J]. Oncotarget, 2017, 8(7), 11144-11159.
Authors:  Li B.;  McCrudden C.M.;  Yuen H.F.;  Xi X.;  Lyu P.; et al.
Favorite | TC[WOS]:32 TC[Scopus]:39 | Submit date:2018/12/19
Brain Tumor  Cd133  Hox  Lim2  Stem Cell